Get accurate results in your research with our Monoclonal Antibodies, which are specially made to target exactly what you require for your research, and will produce consistent, reliable performance in lab tests.
IF (Immunofluorescence) (Confocal immunofluorescence analysis of Hela cells using PAK? Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human lung cancer (left) and gastric cancer (right) with DAB staining using PAK? Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using PAK? Monoclonal Antibody against HeLa (1). Jurkat (2). A549 (3). HEK293 (4) and K562 (5) cell lysate.)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of Hela cells using Pinch-1 Monoclonal Antibody (blue) and negative control (red).)
IF (Immunofluorescence) (Immunofluorescence analysis of HepG2 cells using Pinch-1 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
WB (Western Blot) (Western Blot analysis using Pinch-1 Monoclonal Antibody against A549 (1). Jurkat (2). and HeLa (3) cell lysate.)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of PC-12 cells using Pirh2 Monoclonal Antibody (blue) and negative control (red).)
IF (Immunofluorescence) (Immunofluorescence analysis of Hela cells using Pirh2 Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human Tonsil tissues with AEC staining using Pirh2 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using Pirh2 Monoclonal Antibody against HeLa (1). A549 (2). MCF-7 (3) and PC-12 (4) cell lysate.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human liver carcinoma (A). esophagus carcinoma (B). normal spleen tissue(C). breast carcinoma (D). showing nuclear and cytoplasmic localization with DAB staining using PRAK Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using PRAK Monoclonal Antibody against truncated PRAK recombinant protein.)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of PC-3 cells using PSA Monoclonal Antibody (right) and negative control (left).)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissues. showing cytoplasmic localization with DAB staining using PSA Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using PSA Monoclonal Antibody against truncated PSA recombinant protein.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human Breast tissues with AEC staining using Rak Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using Rak Monoclonal Antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY Rak cDNA (2).)
IF (Immunofluorescence) (Confocal immunofluorescence analysis of HEK293 cells trasfected with extracellular ROR1 (aa30-406)-hIgGFc using ROR1 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye.)
WB (Western Blot) (Western Blot analysis using ROR1 Monoclonal Antibody against extracellular domain of human ROR1 (aa30-423).)
IF (Immunofluorescence) (Confocal immunofluorescence analysis of Hela (left) and L-02 (right) cells using S-100A10 Monoclonal Antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human nerve and ganglion cells with AEC staining using S-100A10 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using S-100A10 Monoclonal Antibody against MCF-7 (1). HepG2 (2) and HeLa (3).)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of NIH/3T3 cells using Smad2 Monoclonal Antibody (blue) and negative control (red).)
IF (Immunofluorescence) (Immunofluorescence analysis of U251 cells using Smad2 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human liver cancer tissues with DAB staining using Smad2 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using Smad2 Monoclonal Antibody against HEK293 (1) and SMAD2-hIgGFc transfected HEK293 (2) cell lysate.)
IF (Immunofluorescence) (Immunofluorescence analysis of HepG2 cells using SMN1 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded breast cancer tissues (left) and testis tissues (right) with DAB staining using SMN1 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using SMN1 Monoclonal Antibody against RAJI (1). Cos7 (2). Jurkat (3). K562 (4). HeLa (5) and HepG2 (6) cell lysate.)
IF (Immunofluorescence) (Immunofluorescence analysis of NIH/3T3 cells using Arg Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
WB (Western Blot) (Western Blot analysis using Arg Monoclonal Antibody against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ABL2 cDNA (2).)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of A431 cells using SOD-1 Monoclonal Antibody (green) and negative control (purple).)
IF (Immunofluorescence) (Confocal immunofluorescence analysis of PANC-1 (left) and SKBR-3 (right) cells using SOD-1 Monoclonal Antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.)
WB (Western Blot) (Western Blot analysis using SOD-1 Monoclonal Antibody against HeLa (1). NIH/3T3 (2). A549 (3) and A431 (4) cell lysate.)
IF (Immunofluorescence) (Immunofluorescence analysis of U251 cells using SUZ12 Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
WB (Western Blot) (Western Blot analysis using SUZ12 Monoclonal Antibody against HEK293 (1) and SUZ12-hIgGFc transfected HEK293 (2) cell lysate.)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of NIH/3T3 cells using TCP-1 ? Monoclonal Antibody (blue) and negative control (red).)
IF (Immunofluorescence) (Immunofluorescence analysis of 3T3-L1 cells using TCP-1 ? Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
WB (Western Blot) (Western Blot analysis using TCP-1 ? Monoclonal Antibody against HeLa (1). MCF-7 (2). Jurkat (3). T47D (4). K562 (5). A431 (6). NIH/3T3 (7). PC-12 (8) and Cos7 (9) cell lysate.)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of K562 cells using TORC1 Monoclonal Antibody (green) and negative control (purple).)
IF (Immunofluorescence) (Immunofluorescence analysis of U251 (left) and NTERA2 (right) cells using TORC1 Monoclonal Antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.)
WB (Western Blot) (Western Blot analysis using TORC1 Monoclonal Antibody against CRTC1-hIgGFc transfected HEK293 cell lysate.)
IF (Immunofluorescence) (Immunofluorescence analysis of NTERA-2 cells using TORC3 Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded breast cancer (left) and ovarian cancer (right) with DAB staining using TORC3 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using TORC3 Monoclonal Antibody against HeLa (1). Jurkat (2). Cos7 (3) and MCF-7 (4) cell lysate.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human normal cardiac muscle tissue. showing cytoplasmic localization with DAB staining using Troponin I-C Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using Troponin I-C Monoclonal Antibody against truncated Troponin I-C recombinant protein.)
IF (Immunofluorescence) (Confocal immunofluorescence analysis of PANC-1 cells using Wnt-10b Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human normal stomach (A). normal liver (B). normal kidney (C) and rectum cancer tissues (D) with DAB staining using Wnt-10b Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using Wnt-10b Monoclonal Antibody against HeLa cell lysate (1).)
IF (Immunofluorescence) (Confocal immunofluorescence analysis of PC-12 cells using Wnt-5a Monoclonal Antibody (green). showing cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human lung cancer (A). thyroid cancer (B). lymph node (C) and brain (D) showing cytoplasmic and extracellular matrix localization with DAB staining using Wnt-5a Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using Wnt-5a Monoclonal Antibody against HEK293 (1) and Wnt-5a-hIgGFc transfected HEK293 cell lysate (2).)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of K562 cells stained with COX4I2 Monoclonal Antibody (red). followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control. normal mouse IgG.)
IF (Immunofluorescence) (Immunofluorescence analysis of HeLa cells using COX4I2 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using COX4I2 Monoclonal Antibody against mouse skeletal muscel. Jurkat cell lysate.)
ICC (Immunocytochemistry) (Immunocytochemistry of HeLa cells using anti-KDM5C/Jarid1C/SMCX mouse mAb diluted 1:150.)
WB (Western Blot) (Western blot detection of KDM5C/Jarid1C/SMCX in Hela and 293 cell lysates using KDM5C/Jarid1C/SMCX mouse mAb (1:1000 diluted).Predicted band size: 176KDa.Observed band size: 220KDa.)
IP (Immunoprecipitation) (Immunoprecipitation analysis of Hela cell lysates using HDAC4 mouse mAb.)
WB (Western Blot) (Western blot detection of HDAC4 in Jurkat.Hela and K562 cell lysates using HDAC4 mouse mAb (1:1000 diluted).Predicted band size: 140KDa.Observed band size: 140KDa.)
IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded Prostate Cancer using HP1-gamma mouse mAb (1/200 dilution).Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).)
ICC (Immunocytochemistry) (Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using anti-HP1-gamma mouse mAb (dilution 1:200).)
ICC (Immunocytochemistry) (Immunocytochemistry staining of HeLa cells fixed with -20? Methanol and using HP1-gamma (200137-5G10.dilution 1:200) mouse mAb (green) and Histone H3.1 (Phospho-Ser10)(310045.dilution 1:200) Rabbit pAb (red). DAPI was used to stain nucleus(blue).)
IP (Immunoprecipitation) (Immunoprecipitation analysis of Hela cell lysates using HP1-gamma mouse mAb.)
WB (Western Blot) (Western blot detection of HP1-gamma in Hela.3T3.C6.COS7 and CHO-K1 cell lysates using HP1-gamma mouse mAb (1:1000 diluted).Predicted band size:22KDa.Observed band size:22KDa.)
WB (Western Blot) (Western blot detection of POU5F1/OCT4 in F9 cell lysates using POU5F1/OCT4 mouse mAb (1:1000 diluted).Predicted band size: 45KDa.Observed band size: 45KDa.)
WB (Western Blot) (Western blot detection of POU5F1/OCT4 in 20ug and 40ug mESC cell lysates using POU5F1/OCT4 mouse mAb (1:1000 diluted).Predicted band size: 45KDa.Observed band size: 45KDa.)
ICC (Immunocytochemistry) (Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using anti-KAP1/TIF1 beta mouse mAb (dilution 1:100).)
IHC (Immunohistochemistry) (IHC of paraffin-embedded human Spleen using anti-KAP1/TIF1 beta diluted 1/500-1/1000.)
IP (Immunoprecipitation) (Immunoprecipitation analysis of Hela cell lysates using KAP1/TIF1 beta mouse mAb.)
WB (Western Blot) (Western blot detection of KAP1/TIF1 beta in 293T and HepG2 cell lysates using KAP1/TIF1 beta mouse mAb (1:1000 diluted).Observed band size: 110KDa.)
IP (Immunoprecipitation) (Immunoprecipitation analysis of Hela cell lysates using Hsp70 (C-terminus) mouse mAb.)
WB (Western Blot) (Western blot detection of Hsp70(C-terminus) in Hela and HsHela cell lysates using Hsp70(C-terminus) mouse mAb (1:1000 diluted).Predicted band size: 70KDa.Observed band size: 70KDa.)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of PC-2 cells using CDC2 Monoclonal Antibody (green) and negative control (purple).)
IF (Immunofluorescence) (Immunofluorescence analysis of Hela cells using CDC2 Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
WB (Western Blot) (Western Blot analysis using CDC2 Monoclonal Antibody against Jurkat (1) cell lysate.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded rectum cancer tissues (left) and placenta tissues (right) with DAB staining using Cdk9 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using Cdk9 Monoclonal Antibody against HEK293 (1) and CDK9-hIgGFc transfected HEK293 (2) cell lysate.)
IF (Immunofluorescence) (Immunofluorescence analysis of U251 cells using c-Rel Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded endometrial cancer tissues (left) and liver cancer tissues (right) with DAB staining using c-Rel Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using c-Rel Monoclonal Antibody against Jurkat (1). NIH/3T3 (2). HeLa (3). HEK293 (4) and RAJI (5) cell lysate.)
IF (Immunofluorescence) (Immunofluorescence staining of methanol-fixed Eca-109 (left) and HepG2 (right) cells showing cytoplasmic localization using Cytokeratin (Pan) Monoclonal Antibody.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human lung squamous cell carcinoma (A). normal hepatocyte (B). colon adenocacinoma (C). normal stomach tissue (D). showing cytoplasmic and membrane localization with DAB staining using Cytokeratin (Pan) M)
WB (Western Blot) (Western Blot analysis using Cytokeratin (Pan) Monoclonal Antibody against truncated CK5 recombinant protein.)
IF (Immunofluorescence) (Immunofluorescence analysis of NIH/3T3 cells using EGF Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
WB (Western Blot) (Western Blot analysis using EGF Monoclonal Antibody against EGF-hIgGFc transfected HEK293 cell lysate.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human Breast tissues with AEC staining using EphA7 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using EphA7 Monoclonal Antibody against truncated GST-EphA7 recombinant protein (1) and truncated EphA7 (aa25-556)-hIgGFc transfected CHOK1 cell lysate (2).)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human lung cancer (left) and colon cancer (right) showing cytoplasmic localization with DAB staining using EphB1 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using EphB1 Monoclonal Antibody against MDA-MB-468 (1). MDA-MB-453 (2). MCF-7 (3). T47D (4) and SKBR-3 (5) cell lysate.)
IF (Immunofluorescence) (Immunofluorescence analysis of Hela (left) and HepG2 (right) cells using EphB2 Monoclonal Antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.)
WB (Western Blot) (Western Blot analysis using EphB2 Monoclonal Antibody against truncated EphB2 recombinant protein (1) and extracellular EphB2(aa19-476)-hIgGFc transfected CHO-K1 cell lysate(2).)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human Small Intestine. muscularis propria tissues with AEC staining using GATA-3 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using GATA-3 Monoclonal Antibody against GATA3-hIgGFc transfected HEK293 cell lysate.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded lung cancer tissues (left) and human rectum tissues (right) with DAB staining using GKLF Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using GKLF Monoclonal Antibody against KLF4 (aa2-470)-hIgGFc transfected HEK293 (1) and HEK293 (2) cell lysate.)
FCM/FACS (Flow Cytometry) (Flow cytometric analysis of K562 cells using Glycogen Synthase 1 Monoclonal Antibody (green) and negative control (purple).)
WB (Western Blot) (Western Blot analysis using Glycogen Synthase 1 Monoclonal Antibody against HeLa (1) and HEK293 (2) cell lysate.)
IF (Immunofluorescence) (Immunofluorescence analysis of NIH/3T3 cells using GRK 2 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded endometrial cancer tissues (left) and cervical cancer tissues (right) with DAB staining using GRK 2 Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using GRK 2 Monoclonal Antibody against HeLa (1). Jurkat (2). MOLT4 (3). RAJI (4). THP-1 (5). L1210 (6). Cos7 (7). PC-12 (8). and NIH/3T3 (9) cell lysate.)
IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded human colon cancer (left) and ancreas cancer (right). showing cytoplasmic localization with DAB staining using Hck Monoclonal Antibody.)
WB (Western Blot) (Western Blot analysis using Hck Monoclonal Antibody against truncated HCK recombinant protein (1) and full-length HCK-GFP transfected CHO-K1 cell lysate (2).)
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Pricing
What are Monoclonal Antibodies?
Monoclonal antibodies are specialized laboratory-produced proteins developed for binding to specific biological antigens or other molecular targets. Since they come from a single cell (or clone), they are especially consistent and accurate in the data they are involved in producing.
This type of antibody material has been shown to be a powerful tool in finding and subsequently destroying harmful cells in an organism, such as those found in cancers or various autoimmune diseases. This makes them excellent aids in medical testing and research, which is why they are so widely used.
AAA Biotech offers a comprehensive range of high-quality monoclonal antibodies that perform effectively in various laboratory tests, including (amongst others) ELISA, western blotting, immunohistochemistry, and flow cytometry. All of the products in our catalog are thoroughly quality tested to make sure that they are reliable and will consistently perform well in your research.
What Are The Uses of Monoclonal Antibodies
Monoclonal antibodies are used in many lab tests, including (amongst others) ELISA, western blotting, immunohistochemistry, and flow cytometry.
ELISA is a test that helps detect a specific substance/analyte in a sample. It uses antibodies (often monoclonal) bound to a solid surface (such as the well of a microplate) to “capture” the substance/analyte in the sample and immobilize it so that the detection antibody component can then bind to it and produce a signal, which can then be measured.
Western blotting identifies specific proteins in a sample. The sample is first separated on a gel, and then antibodies are applied that will typically bind to the target, which will all be localized to a single band in a lane.
Immunohistochemistry helps locate specific proteins in cells or tissue samples using antibodies.
Flow cytometry looks at and sorts cells. It uses antibodies that are conjugated to reporter molecules called “fluorophores”, which, under special lights, emit light themselves, which can then be measured by a detector instrument.
How Monoclonal Antibodies Are Used as Medicine?
Please note that all of the products listed in AAA Biotech’s catalog are strictly for research-use only (RUO).
Monoclonal antibodies can also be used as therapeutic/medical treatments, particularly in the context of cancers. They are designed to find and bind to specific cells or proteins, helping the immune system recognize and attack the cancer. These treatments work in different ways, such as:
Radioimmunotherapy attaches a small amount of radioactive molecule to the antibody, so it delivers the radiation directly to the cancer cells that the antibody is specifically binding to.
Antibody-directed enzyme prodrug therapy uses antibodies that are specifically bound to special enzymes. These enzymes activate a harmless drug in the body and turn it into a cancer-killing drug only near the cancer cells—this helps avoid harming healthy cells.
Immunoliposomes are tiny “bubbles” filled with medicine/drug and coated with antibodies. They carry the drug straight to the cancer cells.
Why Buy Monoclonal Antibodies From Us?
At AAA Biotech, we provide high-performance monoclonal antibodies designed to support a wide range of research needs.
1. Validated for Versatile Applications
The antibodies in our catalog are extensively validated and compatible with multiple techniques, including (but not limited to) ELISA, flow cytometry (FC), immunocytochemistry (ICC), immunofluorescence (IF), immunohistochemistry (IHC), immunoprecipitation (IP), and western blotting (WB).
2. Wide Selection & Specialized Options
We offer antibodies for common and rare species, that are available in various conjugated forms, and also in recombinant formats. Essentially, there is almost anything one might need to meet their experimental model’s requirements.
3. High-Quality Proteins
Our proteins meet high purity standards—90% or more as confirmed by SDS-PAGE. Many are available with tags like His, Flag, GST, or MBP, and we also supply native and biologically active proteins for functional studies.
Frequently Asked Questions
1. Are your monoclonal antibodies validated for specific applications?
Yes, our antibodies are tested and validated for use in methods such as ELISA, western blot, IHC, flow cytometry, and more. Refer to specific product pages or datasheets for individual product information.
2. How do I choose the right monoclonal antibody for my application?
Review the product details directly for application validation, species reactivity, and target information. You may also contact our support team at any time for help.
3. How quickly can I receive my order?
Most orders are processed and shipped within 1–3 business days, depending on product availability and your shipping location.
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