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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 2150-2200 of 2567 product results


Tumor Necrosis Factor Receptor 2 Fusion Protein, Active Protein (Cat# AAA38200)

No reviews yet
Full Name
Recombinant Human Tumor Necrosis Factor Receptor 2 Fusion Protein
Gene Names
TNFRSF1B; p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC.(c) Analysis by SDS-PAGE.
Pricing

Disulfide Isomerase, Active Protein (Cat# AAA38241)

No reviews yet
Full Name
Recombinant Human Protein Disulfide Isomerase
Gene Names
P4HB; DSI; GIT; PDI; PHDB; PDIA1; PO4DB; PO4HB; PROHB; ERBA2L; P4Hbeta
Purity
Greater than 95.0% as determined by a) Analysis by RP-HPLC. b) Analysis by SDS-PAGE.
Pricing

Tyrosine Phosphatase Non Receptor Type-1, Active Protein (Cat# AAA38391)

No reviews yet
Full Name
Recombinant Human Protein Tyrosine Phosphatase Non Receptor Type-1
Gene Names
PTPN1; PTP1B
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Fibroblast Growth Factor Receptor-2, Active Protein (Cat# AAA38396)

No reviews yet
Full Name
Recombinant Human Fibroblast Growth Factor Receptor-2
Gene Names
FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
Purity
Greater than 90.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Vascular Endothelial Growth Factor receptor-2 Fc Chimera, Active Protein (Cat# AAA38400)

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Full Name
Recombinant Human Vascular Endothelial Growth Factor receptor-2 Fc Chimera
Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing

Coagulation Factor VIII, Active Protein (Cat# AAA38430)

No reviews yet
Full Name
Recombinant Human Coagulation Factor VIII
Gene Names
F8; AHF; F8B; F8C; HEMA; FVIII; DXS1253E
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing

Insulin Like Growth Factor-1 Des, Active Protein (Cat# AAA38547)

No reviews yet
Full Name
Recombinant Human Insulin Like Growth Factor-1 Des (1-3)
Gene Names
IGF1; IGFI; IGF-I; IGF1A
Purity
Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing

Pegylated Granulocyte-Colony, Active Protein (Cat# AAA38985)

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Full Name
Recombinant Human Pegylated Granulocyte-Colony Stimulating Factor
Gene Names
CSF3; GCSF; CSF3OS; C17orf33
Purity
Greater than 95.0% as determined by SEC-HPLC.
Pricing

Matrix Metalloproteinase-1, Active Protein (Cat# AAA39015)

No reviews yet
Full Name
Recombinant Human Matrix Metalloproteinase-1, HEK
Gene Names
MMP1; CLG; CLGN
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing

Disulfide Isomerase A6, Active Protein (Cat# AAA39147)

No reviews yet
Full Name
Recombinant Human Protein Disulfide Isomerase A6, Active
Gene Names
PDIA6; P5; ERP5; TXNDC7
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing

beta-Human Chorionic Gonadotrophin, Active Protein (Cat# AAA44799)

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Full Name
beta-Human Chorionic Gonadotropin (b-hCG)
Purity
>98% (SDS-PAGE)
Pricing

Pepsinogen II, Active Protein (Cat# AAA44860)

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Full Name
Pepsinogen II (PGII/PGC), Human Gastric Mucosa
Gene Names
PGC; PEPC; PGII
Applications
Western Blot
Purity
>90% (SDS-PAGE) may contain minor cleavage products.
Pricing
product-image-AAA150099_BIOACTIVITY11.jpg Bioactivity (Figure. The binding activity of FGF23 with FGFR2.Fibroblast growth factor 23 or FGF23 is a member of the fibroblast growth factor (FGF) family which is responsible for phosphate and vitamin D metabolism. The main function of FGF23 seems to be regulation of phosphate concentration in plasma. FGF23 decreases the reabsorption and increases excretion of phosphate and suppress 1-alpha-hydroxylase, reducing its ability to activate vitamin D and subsequently impairing calcium absorption. Besides, Fibroblast Growth Factor Receptor 2 (FGFR2) has been identified as an interactor of FGF23, thus a binding ELISA assay was conducted to detect the interaction of recombinant human FGF23 and recombinant human FGFR2. Briefly, FGF23 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to FGFR2-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-FGF23 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of FGF23 and FGFR2 was shown in Figure 1, and this effect was in a dose dependent manner.)

Fibroblast Growth Factor 23, Active Protein (Cat# AAA150099)

No reviews yet
Full Name
Active Fibroblast Growth Factor 23 (FGF23)
Gene Names
FGF23; ADHR; FGFN; HYPF; HFTC2; HPDR2; PHPTC
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150102_WB8.png WB (Western Blot) (Sample: Recombinant Lpa, Human;Antibody: Rabbit Anti-Human Lpa Ab)

Lipoprotein, a, Active Protein (Cat# AAA150102)

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Full Name
Active Lipoprotein, a (Lpa)
Gene Names
LPA; LP; AK38; APOA
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
product-image-AAA177000_SDS_PAGE15.jpg SDS-PAGE

ACE2, Active Protein (Cat# AAA177000)

No reviews yet
Full Name
Recombinant Human ACE2 Protein (Avi-His Tag)
Gene Names
ACE2; ACEH
Purity
> 95 % as determined by reducing SDS-PAGE.
Pricing
product-image-AAA48521_SDS_PAGE15.jpg SDS-PAGE

GSTM1, Active Protein (Cat# AAA48521)

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Full Name
GSTM1, 1-218aa, Mouse, E Coli (Bioactivity Validated)
Gene Names
Gstm1; Gstb1; Gstb-1
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing

BAFF R/TNFRSF13C, Active Protein (Cat# AAA48988)

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Full Name
Recombinant human BAFF R/TNFRSF13C protein
Gene Names
TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
product-image-AAA41021_BIOACTIVITY13.jpg Bioactivity

COVID 19 Spike S1 Protein Coronavirus, Active Protein (Cat# AAA41021)

No reviews yet
Full Name
Recombinant SARS-CoV-2 (2019-nCoV) S1 Protein
Applications
Immunogen
Purity
>90% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue staining.

ACE2, Active Protein (Cat# AAA78494)

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Full Name
Human ACE2 Protein (Fc Tag)
Purity
>=90% (SDS-PAGE)
Pricing

Adiponectin (ACRP30), Active Protein (Cat# AAA79125)

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Full Name
Human Adiponectin (ACRP30)
Gene Names
ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1
Reactivity
Human
Purity
> 98% by SDS-PAGE analyses
Pricing

ERYTHROPOIETIN ALPHA, Active Protein (Cat# AAA50528)

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Full Name
RECOMBINANT HUMAN ERYTHROPOIETIN ALPHA
Gene Names
EPO; EP; MVCD2
Applications
Functional Assay
Purity
>98.0% by HPLC analysis and SDS-PAGE
Pricing

IFN GAMMA, Active Protein (Cat# AAA50533)

No reviews yet
Full Name
RECOMBINANT HUMAN INTERFERON GAMMA
Gene Names
IFNG; IFG; IFI
Applications
Western Blot, Functional Assay
Purity
>98% by SDS PAGE and HPLC
Pricing
product-image-AAA258013_SDS_PAGE15.jpg SDS-PAGE

SUMO1, Active Protein (Cat# AAA258013)

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Full Name
SUMO1 Protein, Human, Recombinant (His Tag)
Gene Names
SUMO1; DAP1; GMP1; PIC1; SMT3; UBL1; OFC10; SENP2; SMT3C; SMT3H3
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA258080_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized Human ACE2 (mFc tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H)-His, the EC50 of SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H)-His is 200-800 ng/mL.)

COVID 19 Spike S1+S2 ECD (HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H)-His Coronavirus, Active Protein (Cat# AAA258080)

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Full Name
SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD (HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H)-His Recombinant Protein
Purity
>85% as determined by SDS-PAGE
Pricing
product-image-AAA258143_AD13.png Application Data (Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 60-300 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.)

ALK-1, Active Protein (Cat# AAA258143)

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Full Name
ALK-1 Protein, Mouse, Recombinant (His & hFc Tag)
Gene Names
Acvrl1; Alk1; Acvrlk1; AI115505; AI427544
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA150111_BIOACTIVITY10.png Bioactivity (Surfactant Associated Protein C (SPC) is one of the pulmonary surfactant proteins. It is a membrane protein which manufactures surfactant. The propeptide of pulmonary surfactant C has an N-terminal alpha-helical segment whose suggested function was stabilization of the protein structure, since the latter can irreversibly transform from its native alpha-helical structure to beta-sheet aggregates and form amyloid fibrils. Besides, Monokine Induced By Interferon Gamma (MIg) has been identified as an interactor of SPC, thus a binding ELISA assay was conducted to detect the interaction of recombinant rat SPC and recombinant rat MIg. Briefly, SPC were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to MIg-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-SPC pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of SPC and MIg was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of SPC with MIg.)

Surfactant Protein C, Active Protein (Cat# AAA150111)

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Full Name
Active Surfactant Protein C (SP-C)
Gene Names
Sftpc; SP-C
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA37788_AD15.jpg Application Data

Platelet Factor 4, Active Protein (Cat# AAA37788)

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Full Name
Human Platelet Factor 4
Gene Names
PF4; PF-4; CXCL4; SCYB4
Purity
>95% by SDS-PAGE analysis
Pricing

Fc gamma RIIB/CD32b, Active Protein (Cat# AAA49000)

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Full Name
Recombinant human Fc gamma RIIB/CD32b protein
Gene Names
FCGR2B; CD32; FCG2; CD32B; FCGR2; IGFR2
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing

GFR alpha-1, Active Protein (Cat# AAA49003)

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Full Name
Recombinant human GFR alpha-1 protein
Gene Names
GFRA1; GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1
Applications
Bioactivity, SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing
product-image-AAA48548_SDS_PAGE15.jpg SDS-PAGE (3ug by SDS-PAGE under reducing condition and visualized fby coomassie blue stain.)

Peroxiredoxin 6, Active Protein (Cat# AAA48548)

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Full Name
Peroxiredoxin 6, 1-224aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
PRDX6; PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m
Applications
SDS-PAGE, Enzyme Activity
Purity
> 95% by SDS-PAGE
Pricing
product-image-AAA48367_BIOACTIVITY13.jpg Bioactivity (Mouse LIFR alpha inhibits human LIF (Cat# ATGP3533) induced cell proliferation in the TF-1 human erythroleukemic cells. The ED50 range is )

LIFR alpha, Active Protein (Cat# AAA48367)

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Full Name
Recombinant Mouse LIFR alpha Protein
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing

Bacterial Outer Membrane Protein-A, Active Protein (Cat# AAA38518)

No reviews yet
Full Name
Recombinant Bacterial Outer Membrane Protein-A
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Fibroblast Growth Factor-basic, Active Protein (Cat# AAA38112)

No reviews yet
Full Name
Recombinant Human Fibroblast Growth Factor-basic
Gene Names
FGF2; BFGF; FGFB; FGF-2; HBGF-2
Purity
Greater than 98.0% as determined by SDS-PAGE
Pricing

Granulocyte Macrophage-Colony Stimulating Factor, Active Protein (Cat# AAA38116)

No reviews yet
Full Name
Recombinant Mouse Granulocyte Macrophage-Colony Stimulating Factor
Gene Names
Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Purity
Greater than 98.0% as determined by
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing

Growth Hormone, Active Protein (Cat# AAA38125)

No reviews yet
Full Name
Recombinant Human Growth Hormone Binding Protein; GHBP Human
Gene Names
GHR; GHBP; GHIP
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Tumor Necrosis Factor-alpha, Active Protein (Cat# AAA38134)

No reviews yet
Full Name
Recombinant Mouse Tumor Necrosis Factor-alpha
Gene Names
Tnf; DIF; Tnfa; TNF-a; TNFSF2; Tnfsf1a; TNFalpha; TNF-alpha
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (c) Analysis by SDS-PAGE.
Pricing

Visfatin, Active Protein (Cat# AAA38155)

No reviews yet
Full Name
Recombinant Human Visfatin
Gene Names
NAMPT; VF; PBEF; PBEF1; VISFATIN; 1110035O14Rik
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing

Erythropoietin-alpha Fc/Chimera, Active Protein (Cat# AAA38158)

No reviews yet
Full Name
Recombinant Human Erythropoietin-alpha Fc/Chimera
Gene Names
EPO; EP; MVCD2
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Thrombopoietin, Active Protein (Cat# AAA38170)

No reviews yet
Full Name
Recombinant Mouse Thrombopoietin
Gene Names
Thpo; Ml; Tpo; Mgdf; Mpllg
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Interleukin-2, Active Protein (Cat# AAA38183)

No reviews yet
Full Name
Recombinant Rat Interleukin-2
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Fibroblast Growth Factor-basic, Active Protein (Cat# AAA38184)

No reviews yet
Full Name
Recombinant Mouse Fibroblast Growth Factor-basic
Gene Names
Fgf2; Fgfb; bFGF; Fgf-2
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Granulocyte-Colony Stimulating Factor, Active Protein (Cat# AAA38194)

No reviews yet
Full Name
Recombinant Mouse Granulocyte-Colony Stimulating Factor
Gene Names
Csf3; Csfg; G-CSF; MGI-IG
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Urease, Active Protein (Cat# AAA38249)

No reviews yet
Full Name
Recombinant Urease
Gene Names
URE; F12B7.10; F12B7_10; URE; urease
Purity
Greater than 90.0% as determined by SDS-PAGE
Pricing

Pyrococcus Fruriosus Deoxyuridine Triphosphatase, Active Protein (Cat# AAA38252)

No reviews yet
Full Name
Recombinant Pyrococcus Fruriosus Deoxyuridine Triphosphatase
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing

Staphylokinase, Active Protein (Cat# AAA38257)

No reviews yet
Full Name
Recombinant Staphylokinase
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Kinase A Inactive holoenzyme type 1 alpha, Active Protein (Cat# AAA38385)

No reviews yet
Full Name
Recombinant Protein Kinase A Inactive holoenzyme type 1 alpha
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Tyrosine Phosphatase Non Receptor Type-6, Active Protein (Cat# AAA38392)

No reviews yet
Full Name
Recombinant Human Protein Tyrosine Phosphatase Non Receptor Type-6
Gene Names
PTPN6; HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Coagulation Factor VIII, Active Protein (Cat# AAA38429)

No reviews yet
Full Name
Human Coagulation Factor VIII
Gene Names
F8; AHF; F8B; F8C; HEMA; FVIII; DXS1253E
Pricing

Coagulation Factor VIIa, Active Protein (Cat# AAA38434)

No reviews yet
Full Name
Recombinant Human Coagulation Factor VIIa
Gene Names
F7; SPCA
Purity
Greater than 98.0% as determined by analysis by SDS-PAGE.
Pricing

Monocyte Chemotactic Protein-1, Active Protein (Cat# AAA38085)

No reviews yet
Full Name
Recombinant Mouse Monocyte Chemotactic Protein-1 (CCL2)
Gene Names
Ccl2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594
Purity
Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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