Active Proteins

AAA Biotech provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.

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Application Data (Measured by its ability to inhibit recombinant rmWnt3a induced alkaline phosphatase production by C3H10T 1/2 cells. The ED50 for this effect is 0.05-0.3 ug/mL.)

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DKK1, Active Protein (Cat# AAA258244)

Full Name

DKK1 Protein, Mouse, Recombinant (His Tag)

Gene Names

Dkk1; mdkk-1

Purity

>95% as determined by SDS-PAGE

Pricing

$435/0.05 mg $3,035/1 mg $5,920/2x1 mg $8,645/3x1 mg $11,230/4x1 mg $13,455/5x1 mg

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Application Data (Measured by its ability to bind rat Fc-VEGFC in functional ELISA.)

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Neuropilin-2, Active Protein (Cat# AAA258245)

Full Name

Neuropilin-2 Protein, Mouse, Recombinant (His Tag)

Gene Names

Nrp2; Np2; Np-2; Npn2; Npn-2; 1110048P06Rik

Purity

>95% as determined by SDS-PAGE

Pricing

$490/0.1 mg $955/2x0.1 mg $1,400/3x0.1 mg $1,815/4x0.1 mg $2,015/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized zebrafish EFNB2A-His at 10 ug/ml (100 ul/well) can bind human EphB4-Fc, The EC50 of human EphB4-Fc is 15.5-36.3 ng/ml.)

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EFNB2A, Active Protein (Cat# AAA258249)

Full Name

EFNB2A Protein, Danio rerio (zebrafish), Recombinant (His Tag)

Gene Names

efnb2a; efnb2; ephrin-B2a; id:ibd5072

Purity

>95% as determined by SDS-PAGE

Pricing

$610/0.2 mg $1,180/2x0.2 mg $1,725/3x0.2 mg $2,235/4x0.2 mg $2,530/5x0.2 mg

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Application Data (Measured by its ability to inhibit rhBMP4-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 0.5-2.5 ug/mL in the presence of 50 ng/mL of recombinant human BMP4.)

SDS-PAGE

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BMPR1A/ALK-3, Active Protein (Cat# AAA258253)

Full Name

BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc Tag)

Purity

>95% as determined by SDS-PAGE

Pricing

$325/0.1 mg $625/2x0.1 mg $910/3x0.1 mg $1,180/4x0.1 mg $1,245/5x0.1 mg

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Application Data (Immobilized human EPHA3-His at 10 ug/ml (100 ul/well) can bind canine EFNA5-Fc, The EC50 of canine EFNA5-Fc is 11.5-26.7 ng/ml.)

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Ephrin A5, Active Protein (Cat# AAA258254)

Full Name

Ephrin A5 Protein, Canine, Recombinant (hFc Tag)

Purity

>95% as determined by SDS-PAGE

Pricing

$435/0.1 mg $850/2x0.1 mg $1,235/3x0.1 mg $1,605/4x0.1 mg $1,755/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized canine EFNB2-His at 10 ug/ml (100 ul /well) can bind human EphB4-Fc, The EC50 of human EphB4-Fc is 9-20 ng/ml.)

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Ephrin B2, Active Protein (Cat# AAA258256)

Full Name

Ephrin B2 Protein, Canine, Recombinant (His Tag)

Purity

>95% as determined by SDS-PAGE

Pricing

$435/0.1 mg $850/2x0.1 mg $1,235/3x0.1 mg $1,605/4x0.1 mg $1,755/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized canine NRG1 at 10 ug/ml (100 ul/well) can bind human ErbB4-Fc, The EC50 of human ErbB4-Fc is 0.19-0.43 ug/ml.)

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Neuregulin-1, Active Protein (Cat# AAA258259)

Full Name

Neuregulin-1 Protein, Canine, Recombinant (ECD)

Purity

>95% as determined by SDS-PAGE

Pricing

$435/0.1 mg $850/2x0.1 mg $1,235/3x0.1 mg $1,605/4x0.1 mg $1,755/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized Human ACE2 (mFc tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD(F490L)-His, the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD(F490L)-His is 30-150ng/mL.)

SDS-PAGE

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COVID 19 Spike RBD(F490L)-His Coronavirus, Active Protein (Cat# AAA258104)

Full Name

SARS-CoV-2 (2019-nCoV) Spike RBD(F490L)-His Recombinant Protein

Purity

>95% as determined by SDS-PAGE

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Immobilized ACE2 Protein, Human, Recombinant (mFc Tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD(E484K)-His, the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD(E484K)-His is 7-42ng/mL.)

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COVID 19 Spike RBD(E484K)-His Coronavirus, Active Protein (Cat# AAA258105)

Full Name

SARS-CoV-2 (2019-nCoV) Spike RBD(E484K)-His Recombinant Protein

Purity

>90% as determined by SDS-PAGE

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized ACE2 Protein, Human, Recombinant (mFc Tag)(10108-H05H) at 2ug/mL (100uL/well) can bind SARS-CoV Spike S1+S2 ECD-His Recombinant Protein (S577A, Isolate Tor2)(40634-V08B),the EC50 of SARS-CoV Spike S1+S2 ECD-His Recombinant Protein (S577A, Isolate Tor2)(40634-V08B) is 300-900ng/mL.)

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SARS-CoV Spike S1+S2, Active Protein (Cat# AAA258111)

Full Name

SARS-CoV Spike S1+S2 ECD-His Recombinant Protein (S577A, Isolate Tor2)

Reactivity

SARS

Purity

>90% as determined by SDS-PAGE

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Measured by its ability to inhibit Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is typically 0.4-2 ug/mL in the presence of 300 ng/mL of Recombinant Mouse Wnt-3a.)

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SFRP1, Active Protein (Cat# AAA258118)

Full Name

SFRP1 Protein, Mouse, Recombinant (His Tag)

Purity

>95% as determined by SDS-PAGE

Pricing

$375/0.05 mg $725/2x0.05 mg $1,060/3x0.05 mg $1,370/4x0.05 mg $1,485/5x0.05 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized mouse F7-his at 10 ug/ml (100 ul/well) can bind biotinylated mouse F3-his. The EC50 of biotinylated mouse F3-his is 0.1-0.3 ug/ml.)

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Factor VII, Active Protein (Cat# AAA258119)

Full Name

Factor VII Protein, Mouse, Recombinant (His Tag)

Gene Names

F7; Cf7; FVII; mfVII; AI132620

Purity

>90% as determined by SDS-PAGE

Pricing

$265/0.02 mg $435/0.05 mg $850/2x0.05 mg $1,235/3x0.05 mg $1,605/4x0.05 mg $1,755/5x0.05 mg

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Application Data (Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.1-0.6 ng/mL.)

SDS-PAGE

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FGF2, Active Protein (Cat# AAA258121)

Full Name

FGF2 Protein, Mouse, Recombinant (His Tag)

Purity

>95% as determined by SDS-PAGE

Pricing

$230/0.02 mg $375/0.1 mg $1,565/1 mg $3,045/2x1 mg $4,455/3x1 mg $5,780/4x1 mg $6,835/5x1 mg

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Application Data

SDS-PAGE (Measured by its ability to inhibit the mouse CSF-induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 30-140ng/mL in the presence of 15 ng/mL mouse M-CSF.)

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CSF1R, Active Protein (Cat# AAA258124)

Full Name

CSF1R Protein, Mouse, Recombinant (ECD, hFc Tag)

Gene Names

Csf1r; Fms; CD115; Csfmr; Fim-2; CSF-1R; M-CSFR; M-CSF-R; AI323359

Purity

>95% as determined by SDS-PAGE

Pricing

$435/0.1 mg $2,310/1 mg $4,500/2x1 mg $6,570/3x1 mg $8,530/4x1 mg $10,195/5x1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized recombinant Mouse/Human BDNF Protein (Native) at 10 ug/ml (100 ul/well) can bind biotinylated mouse TrkB-His with a linear range of 10-80 ng/ml.)

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TrkB, Active Protein (Cat# AAA258131)

Full Name

TrkB Protein, Mouse, Recombinant (His Tag)

Gene Names

Ntrk2; Tkrb; trkB; trk-B; GP145-TrkB/GP95-TrkB

Purity

>98% as determined by SDS-PAGE

Pricing

$375/0.05 mg $725/2x0.05 mg $1,060/3x0.05 mg $1,370/4x0.05 mg $1,485/5x0.05 mg

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Application Data (Measured by its ability to inhibit FGF acidic (aFGF / FGF1) dependent proliferation of Balb/c3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.1-0.6 ug/mL.)

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FGFR4, Active Protein (Cat# AAA258142)

Full Name

FGFR4 Protein, Mouse, Recombinant (His & hFc Tag)

Purity

>95% as determined by SDS-PAGE

Pricing

$435/0.1 mg $850/2x0.1 mg $1,235/3x0.1 mg $1,605/4x0.1 mg $1,755/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized mouse PCSK9 at 10 ug/ml (100 ul/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.12 ug/ml.)

SDS-PAGE

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PCSK9, Active Protein (Cat# AAA258147)

Full Name

PCSK9 Protein, Mouse, Recombinant (His Tag)

Gene Names

Pcsk9; FH3; PC9; Narc1; HCHOLA3; AI415265; AI747682

Purity

>95% as determined by SDS-PAGE

Pricing

$220/0.02 mg $435/0.1 mg $2,310/1 mg $4,500/2x1 mg $6,570/3x1 mg $8,530/4x1 mg $10,195/5x1 mg

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Application Data (Immobilized mouse PDPN-Fch at 10 ug/ml (100 ul/well) can bind biotinylated human CLEC1B-His, The EC50 of biotinylated human CLEC1B-His is 0.04-0.08 ug/ml.)

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Podoplanin, Active Protein (Cat# AAA258148)

Full Name

Podoplanin Protein, Mouse, Recombinant (His & hFc Tag)

Gene Names

Pdpn; T1a; Gp38; OTS-8; T1alpha; RANDAM-2; T1-alpha

Purity

>97% as determined by SDS-PAGE

Pricing

$435/0.1 mg $850/2x0.1 mg $1,235/3x0.1 mg $1,605/4x0.1 mg $1,755/5x0.1 mg

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Application Data (Measured by its ability to bind recombinant mouse CD226/DNAM-1. Immobilized recombinant mouse CD155/PVR at 1 ug/ml (100 ul/well) can bind recombinant mouse CD226/DNAM-1 with a linear range of 0.78-100 ng/ml.)

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CD155/PVR, Active Protein (Cat# AAA258149)

Full Name

CD155/PVR Protein, Mouse, Recombinant (His Tag)

Purity

>97% as determined by SDS-PAGE

Pricing

$435/0.1 mg $2,310/1 mg $4,500/2x1 mg $6,570/3x1 mg $8,530/4x1 mg $10,195/5x1 mg

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Application Data (Immobilized human BAFF at 10 ug/ml (100 ul/well) can bind mouse BAFFR-Fc, The EC50 of mouse BAFFR-Fc is 0.14-0.32 ug/ml.)

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BAFFR/TNFRSF13C, Active Protein (Cat# AAA258157)

Full Name

BAFFR/TNFRSF13C Protein, Mouse, Recombinant (hFc Tag)

Gene Names

Tnfrsf13c; Bcmd; Baffr; Bcmd1; BAFF-R; Bcmd-1; Lvis22; 2010006P15Rik

Purity

>90% as determined by SDS-PAGE

Pricing

$435/0.1 mg $850/2x0.1 mg $1,235/3x0.1 mg $1,605/4x0.1 mg $1,755/5x0.1 mg

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Application Data (Measured by its ability to promote proliferation of INS-1 cells. The ED50 for this effect is typically 50-500 ng/mL.)

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Prolactin, Active Protein (Cat# AAA258158)

Full Name

Prolactin Protein, Mouse, Recombinant (His Tag)

Purity

>92% as determined by SDS-PAGE

Pricing

$220/0.02 mg $325/0.1 mg $625/2x0.1 mg $910/3x0.1 mg $1,180/4x0.1 mg $1,245/5x0.1 mg

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Application Data (Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells.The ED50 for this effect is typically 25-100 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.)

SDS-PAGE

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Endoglin/CD105, Active Protein (Cat# AAA258161)

Full Name

Endoglin/CD105 Protein, Mouse, Recombinant (His Tag)

Purity

>97% as determined by SDS-PAGE

Pricing

$490/0.1 mg $955/2x0.1 mg $1,400/3x0.1 mg $1,815/4x0.1 mg $2,015/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized human CTLA4 at 10 ug/mL (100 ul/well) can bind mouse CD80-Fc, The EC50 of mouse CD80-Fc is 28 ng/mL.)

SDS-PAGE

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B7-1, Active Protein (Cat# AAA258163)

Full Name

B7-1 Protein, Mouse, Recombinant (hFc Tag)

Gene Names

Cd80; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17

Purity

>90% as determined by SDS-PAGE

Pricing

$375/0.1 mg $1,945/1 mg $3,785/2x1 mg $5,535/3x1 mg $7,185/4x1 mg $8,540/5x1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized Rat ICOS ligand hFc at 2 ug/mL (100 uL/well) can bind Mouse ICOS His, the EC50 of Mouse ICOS His is 150-800 ng/mL.)

SDS-PAGE

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ICOS, Active Protein (Cat# AAA258165)

Full Name

ICOS Protein, Mouse, Recombinant (His Tag)

Gene Names

Icos; H4; CCLP; AILIM; CRP-1; Ly115

Purity

>90% as determined by SDS-PAGE

Pricing

$435/0.1 mg $2,310/1 mg $4,500/2x1 mg $6,570/3x1 mg $8,530/4x1 mg $10,195/5x1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized human HHLA2h at 10 ug/mL (100 uL/well) can bind human TMIGD2-Fc3, the EC50 of human TMIGD2-Fc3 is 50-200 ng/mL.)

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TMIGD2, Active Protein (Cat# AAA258027)

Full Name

TMIGD2 Protein, Human, Recombinant (ECD, hFc Tag)

Gene Names

TMIGD2; CD28H; IGPR1; IGPR-1

Purity

>95% as determined by SDS-PAGE

Pricing

$490/0.1 mg $2,310/1 mg $4,500/2x1 mg $6,570/3x1 mg $8,530/4x1 mg $10,195/5x1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized human His-NKG2D(78-216) at 10 ug/ml (100 ul/well) can bind RAET1L-Fc, The EC50 of RAET1L-Fc is 13-30 ng/ml.)

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ULBP6/RAET1L, Active Protein (Cat# AAA258035)

Full Name

ULBP6/RAET1L Protein, Human, Recombinant (hFc Tag)

Purity

>90% as determined by SDS-PAGE

Pricing

$435/0.1 mg $850/2x0.1 mg $1,235/3x0.1 mg $1,605/4x0.1 mg $1,755/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized human NCR3 at 10ug/mL (100uL/well) can bind human B7-H6 (16140-H02H), the EC50 of human B7-H6 is 20-100 ng/mL.)

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B7-H6, Active Protein (Cat# AAA258050)

Full Name

B7-H6 Protein, Human, Recombinant (hFc Tag)

Gene Names

NCR3LG1; B7H6; B7-H6; DKFZp686O24166

Purity

>95% as determined by SDS-PAGE

Pricing

$610/0.2 mg $1,180/2x0.2 mg $1,725/3x0.2 mg $2,235/4x0.2 mg $2,530/5x0.2 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized Human ACE2 (mFc tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike S1(K417N, E484K, N501Y, D614G)-His, the EC50 of SARS-CoV-2 (2019-nCoV) Spike S1(K417N, E484K, N501Y, D614G)-His is 15-90 ng/mL.)

SDS-PAGE

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COVID 19 Spike S1(K417N, E484K, N501Y, D614G)-His Coronavirus, Active Protein (Cat# AAA258087)

Full Name

SARS-CoV-2 (2019-nCoV) Spike S1(K417N, E484K, N501Y, D614G)-His Recombinant Protein

Purity

>90% as determined by SDS-PAGE

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized Human ACE2 (mFc tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, N501Y, D614G)-His, the EC50 of SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, N501Y, D614G)-His is 8-50 ng/mL.)

SDS-PAGE

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COVID 19 Spike S1(HV69-70 deletion, N501Y, D614G)-His Coronavirus, Active Protein (Cat# AAA258091)

Full Name

SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, N501Y, D614G)-His Recombinant Protein

Purity

>90% as determined by SDS-PAGE

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag)(10108-H05H) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike S1-AVI & His Recombinant Protein, Biotinylated (40591-V27H-B),the EC50 of SARS-CoV-2 (2019-nCoV) Spike S1-AVI & His Recombinant Protein, Biotinylated (40591-V27H-B) is 400-800 ng/mL.)

Application Data

SDS-PAGE

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COVID 19 Spike S1-AVI & His Coronavirus, Active Protein (Cat# AAA258092)

Full Name

SARS-CoV-2 (2019-nCoV) Spike S1-AVI & His Recombinant Protein, Biotinylated

Purity

>95% as determined by SDS-PAGE >95% as determined by SEC-HPLC.

Pricing

$490/0.02 mg $955/2x0.02 mg $1,400/3x0.02 mg $1,815/4x0.02 mg $2,015/5x0.02 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag)(10108-H05H) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD-His (V367F) Recombinant Protein (40592-V08H1), the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD-His (V367F) Recombinant Protein (40592-V08H1) is 20-50 ng/mL.)

SDS-PAGE

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COVID 19 Spike RBD-His (V367F) Coronavirus, Active Protein (Cat# AAA258094)

Full Name

SARS-CoV-2 (2019-nCoV) Spike RBD-His (V367F) Recombinant Protein

Purity

>95% as determined by SDS-PAGE

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag)(10108-H05H) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD-His (F342L) Recombinant Protein (40592-V08H6), the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD-His (F342L) Recombinant Protein (40592-V08H6) is 20-50 ng/mL.)

SDS-PAGE

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COVID 19 Spike RBD-His (F342L) Coronavirus, Active Protein (Cat# AAA258098)

Full Name

SARS-CoV-2 (2019-nCoV) Spike RBD-His (F342L) Recombinant Protein

Purity

>95% as determined by SDS-PAGE

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag)(10108-H05H) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD(G476S)-His Recombiant Protein (40592-V08H8), the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD(G476S)-His Recombiant Protein (40592-V08H8) is 25-60 ng/mL.)

SDS-PAGE

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COVID 19 Spike RBD(G476S)-His Coronavirus, Active Protein (Cat# AAA258100)

Full Name

SARS-CoV-2 (2019-nCoV) Spike RBD(G476S)-His Recombinant Protein

Purity

>95% as determined by SDS-PAGE

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 5-30 ng/mL.)

SDS-PAGE

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SCF, Active Protein (Cat# AAA258166)

Full Name

SCF Protein, Mouse, Recombinant (ECD, His Tag)

Gene Names

Kitl; Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; blz; Kitlg; contrasted

Purity

>95% as determined by SDS-PAGE

Pricing

$310/0.02 mg $555/0.1 mg $2,745/1 mg $5,350/2x1 mg $7,815/3x1 mg $10,145/4x1 mg $12,165/5x1 mg

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Application Data

SDS-PAGE (Measured by its binding ability in a functional ELISA. Immobilized VEGF165 can bind mNRP1h, the EC50 of mNRP1h is 30-120 ng/mL.)

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Neuropilin-1, Active Protein (Cat# AAA258169)

Full Name

Neuropilin-1 Protein, Mouse, Recombinant (ECD, His Tag)

Gene Names

Nrp1; Nrp; NP-1; Npn1; NPN-1; C530029I03

Purity

>95% as determined by SDS-PAGE

Pricing

$325/0.05 mg $2,680/1 mg $5,220/2x1 mg $7,625/3x1 mg $9,895/4x1 mg $11,850/5x1 mg

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Application Data (Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 0.1-0.8 ng/mL.)

SDS-PAGE

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Interferon alpha 2/IFNA2, Active Protein (Cat# AAA258171)

Full Name

Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc Tag)

Gene Names

Ifna2; Ifa2

Purity

>88% as determined by SDS-PAGE

Pricing

$490/0.1 mg $955/2x0.1 mg $1,400/3x0.1 mg $1,815/4x0.1 mg $2,015/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized mouse VEGFR3-His at 10 ug/mL (100 ul/well) can bind mouse Fc-VEGFD, The EC50 of mouse Fc-VEGFD is 44 ng/mL.)

SDS-PAGE

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VEGFR3/FLT4, Active Protein (Cat# AAA258176)

Full Name

VEGFR3/FLT4 Protein, Mouse, Recombinant (His Tag)

Gene Names

Flt4; Chy; Flt-4; VEGFR3; VEGFR-3; AI323512

Purity

>97% as determined by SDS-PAGE

Pricing

$435/0.1 mg $1,690/1 mg $3,290/2x1 mg $4,805/3x1 mg $6,240/4x1 mg $7,410/5x1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized Mouse EphA2 at 2 ug/ml (100 ul/well) can bind mouse EphrinA1 with a linear range of 0.16-20 ng/ml.)

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Ephrin-A1, Active Protein (Cat# AAA258178)

Full Name

Ephrin-A1 Protein, Mouse, Recombinant (hFc Tag)

Gene Names

Cd99l2; Xap89; Mic2l1; AW548191

Purity

>85% as determined by SDS-PAGE

Pricing

$435/0.1 mg $850/2x0.1 mg $1,235/3x0.1 mg $1,605/4x0.1 mg $1,755/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized mouse EphrinA3 at 1 ug/ml (100 ul/well) can bind mouse EPHA6 with a linear ranger of 6.25-400 ng/ml.)

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Ephrin A3, Active Protein (Cat# AAA258179)

Full Name

Ephrin A3 Protein, Mouse, Recombinant (His Tag)

Gene Names

Efna3; Epl3; EFL-2; Ehk1-L; LERK-3; AW494418

Purity

>92% as determined by SDS-PAGE

Pricing

$490/0.1 mg $955/2x0.1 mg $1,400/3x0.1 mg $1,815/4x0.1 mg $2,015/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. 1. Immobilized human EphA7 at 2 ug/ml (100 ul/well) can bind mouse EphrinA4 Fc Chimera with a linear range of 0.08-10 ng/ml. 2. Immobilized mouse EphA7 at 2 ug/ml (100 ul/well) can bind mouse EphrinA4 Fc Chimera with a linear range of 0.08-10 ng/ml.)

SDS-PAGE

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Ephrin A4, Active Protein (Cat# AAA258180)

Full Name

Ephrin A4 Protein, Mouse, Recombinant (hFc Tag)

Purity

>92% as determined by SDS-PAGE

Pricing

$435/0.1 mg $850/2x0.1 mg $1,235/3x0.1 mg $1,605/4x0.1 mg $1,755/5x0.1 mg

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Application Data (Measured by its binding ability in a functional ELISA. Immobilized mouse IFNG-His at 10 ug/ml (100 ul/well) can bind mouse IFNGR1-Fc. The EC50 of IFNGR1-Fc is 58.2-135.9 ng/ml.)

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IFNGR1, Active Protein (Cat# AAA258195)

Full Name

IFNGR1 Protein, Mouse, Recombinant (hFc Tag)

Gene Names

Ifngr1; Ifgr; CD119; Ifngr; Nktar; IFN-gammaR

Purity

>95% as determined by SDS-PAGE

Pricing

$325/0.1 mg $625/2x0.1 mg $910/3x0.1 mg $1,180/4x0.1 mg $1,245/5x0.1 mg

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Application Data (Measured in antiviral assay using L929 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is typically 20-80 ng/mL.)

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Interferon Gamma, Active Protein (Cat# AAA258197)

Full Name

Interferon Gamma Protein, Mouse, Recombinant (hFc Tag)

Gene Names

Ifng; Ifg; IFN-g

Purity

>92% as determined by SDS-PAGE

Pricing

$375/0.1 mg $725/2x0.1 mg $1,060/3x0.1 mg $1,370/4x0.1 mg $1,485/5x0.1 mg

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Application Data (Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV).The ED50 for this effect is 0.05-0.3 ng/mL.)

Application Data (Measured by its binding ability in a functional ELISA. Immobilized Mouse Interferon Gamma at 2 ug/ml (100 ul/well) can bind Mouse IFNGR1 hFc, the EC50 of Mouse IFNGR1 hFc is7.0-30.0 ng/mL.)

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Interferon Gamma, Active Protein (Cat# AAA258199)

Full Name

Interferon Gamma Protein, Mouse, Recombinant

Purity

>85% as determined by SDS-PAGE

Pricing

$180/0.02 mg $250/0.1 mg $1,045/1 mg $2,030/2x1 mg $2,970/3x1 mg $3,855/4x1 mg $4,495/5x1 mg

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Application Data (Active alpha synuclein aggregate seeds the formation of new alpha Synuclein aggregates from the pool of active alpha Synuclein monomers. Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures, such as those in alpha Synuclein aggregates. Upon binding, the emission spectrum of the dye experiences a red-shift, and increased fluorescence intensity. Thioflavin T emission curves show increased fluorescence (correlated to alpha Synuclein protein aggregation) over time when 10 nM of active alpha Synuclein aggregate is combined with 100 uM of active alpha Synuclein monomer, as compared to when 100 uM of active alpha Synuclein monomer is combined with 10 nM of control alpha Synuclein aggregate, or 100 uM of control alpha Synuclein monomer is combined with 10 nM of control alpha Synuclein aggregate. Thioflavin T ex = 450 nm, em = 485 nm.)

Application Data (Primary rat hippocampal neurons show lewy body inclusion formation when treated with active Alpha Synuclein Protein Aggregate at 4 ug/ml (D-F), but not when treated with control Alpha Synuclein Protein Aggregate at 4 ug/ml (A-C). Tissue: Primary hippocampal neurons. Species: Sprague-Dawley rat. Fixation: 4% formaldehyde made from PFA. Primary Antibody: Mouse anti-pSer129 Antibody at 1:1000 24 hours at 4 degree C. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:700 for 1 hours at RT. Counterstain: Hoechst (blue) nuclear stain at 1:4000 for 1 hour at RT. Localization: Lewy body incluscions. Magnification: 20x.)

SDS-PAGE (SDS-PAGE of ~14 kDa Human Recombinant Alpha Synuclein Protein Aggregate. Lane 1: Molecular Weight Ladder (MW). Lane 2: Alpha Synuclein Protein Aggregate (SPR-317).)

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Alpha Synuclein, Active Protein (Cat# AAA253922)

Full Name

Alpha Synuclein Protein

Gene Names

SNCA; PD1; NACP; PARK1; PARK4

Applications

Western Blot

Purity

Ion-exchange Purified

Pricing

$630/0.1 mg $890/2x0.1 mg $1,620/5x0.1 mg

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SDS-PAGE (SDS-PAGE of ~14 kDa Active Human Recombinant Alpha Synuclein Protein Aggregate. Lane 1: Molecular Weight Ladder (MW). Lane 2: Active Alpha Synuclein Protein Aggregate.)

Application Data (Active alpha synuclein aggregate seeds the formation of new alpha Synuclein aggregates from the pool of active alpha Synuclein monomers. Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures, such as those in alpha Synuclein aggregates. Upon binding, the emission spectrum of the dye experiences a red-shift, and increased fluorescence intensity. Thioflavin T emission curves show increased fluorescence (correlated to alpha Synuclein protein aggregation) over time when 10 nM of active alpha Synuclein aggregate is combined with 100 uM of active alpha Synuclein monomer, as compared to active alpha Synuclein aggregate and active alpha Synuclein monomer alone. Thioflavin T ex = 450 nm, em = 485 nm.)

Application Data (Primary rat hippocampal neurons show lewy body inclusion formation when treated with active Alpha Synuclein Protein Aggregate at 4 ug/ml (D-F), but not when treated with control Alpha Synuclein Protein Aggregate at 4 ug/ml (A-C). Tissue: Primary hippocampal neurons. Species: Sprague-Dawley rat. Fixation: 4% formaldehyde from PFA. Primary Antibody: Mouse anti-pSer129 Antibody at 1:1000 24 hours at 4 degree C. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:700 for 1 hours at RT. Counterstain: Hoechst (blue) nuclear stain at 1:4000 for 1 hour at RT. Localization: Lewy body incluscions. Magnification: 20x.)

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Alpha Synuclein, Active Protein (Cat# AAA253923)

Full Name

Alpha Synuclein Protein

Gene Names

SNCA; PD1; NACP; PARK1; PARK4

Applications

Western Blot

Purity

>95%
Ion-exchange Purified

Pricing

$630/0.1 mg $890/2x0.1 mg $1,620/5x0.1 mg

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SDS-PAGE (SDS-PAGE of ~14 kDa Active Mouse Recombinant Alpha Synuclein Protein Monomer (SPR-323). Lane 1: Molecular Weight Ladder (MW). Lane 2: Active Alpha Synuclein Protein Monomer (2 ug) (SPR-323).)

Application Data (Active alpha synuclein aggregate (SPR-324) seeds the formation of new alpha Synuclein aggregates from the pool of active alpha Synuclein monomers (SPR-323). Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures, such as those in alpha Synuclein aggregates. Upon binding, the emission spectrum of the dye experiences a red-shift, and increased fluorescence intensity. Thioflavin T emission curves show increased fluorescence (correlated to alpha Synuclein protein aggregation) over time when 10 nM of active alpha Synuclein aggregate (SPR-324) is combined with 100 uM of active alpha Synuclein monomer (SPR-323), as compared to active alpha Synuclein aggregate (SPR-324) and active alpha Synuclein monomer (SPR-323) alone. Thioflavin T ex = 450 nm, em = 485 nm.)

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Alpha Synuclein, Active Protein (Cat# AAA253924)

Full Name

Alpha Synuclein Protein

Gene Names

Snca; NACP; alphaSYN; alpha-Syn

Applications

Western Blot

Purity

>95%
Ion-exchange Purified

Pricing

$630/0.1 mg $890/2x0.1 mg $1,620/5x0.1 mg

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Application Data (Immobilized ACE2 Protein, Human, Recombinant (mFc Tag)(Cat:10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 (BA.2.75) Spike RBD Protein (His Tag)(Cat:AAA258568), the EC50 is 3-10ng/mL.)

Application Data

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COVID 19 (BA.2.75) Spike RBD Coronavirus, Active Protein (Cat# AAA258568)

Full Name

SARS-CoV-2 (BA.2.75) Spike RBD Protein (His Tag)

Purity

>95% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 (BA.4.6) Spike S1+S2 trimer Protein (ECD, His Tag)(Cat: AAA258586), the EC50 is 8-24 ng/mL.)

Application Data

Application Data

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COVID 19 (BA.4.6) Spike S1+S2 trimer Coronavirus, Active Protein (Cat# AAA258586)

Full Name

SARS-CoV-2 (BA.4.6) Spike S1+S2 trimer Protein (ECD, His Tag)

Purity

>95% as determined by SDS-PAGE. >90% as determined by SEC-HPLC.

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 (BA.3) Spike RBD Protein (R319-K537, His Tag)(Cat: AAA258588), the EC50 is 7-21 ng/mL.)

Application Data

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COVID 19 (BA.3) Spike RBD Coronavirus, Active Protein (Cat# AAA258588)

Full Name

SARS-CoV-2 (BA.3) Spike RBD Protein (R319-K537, His Tag)

Purity

>95% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.

Pricing

$610/0.1 mg $1,180/2x0.1 mg $1,725/3x0.1 mg $2,235/4x0.1 mg $2,530/5x0.1 mg

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Application Data (Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2(BA.4/BA.5)Spike RBD Protein(His&AVI Tag),Biotinylated (Cat: AAA258592), the EC50 is 15-45 ng/mL.)

Application Data

Application Data

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COVID 19 (BA.4/BA.5) Spike RBD Coronavirus, Active Protein (Cat# AAA258592)

Full Name

SARS-CoV-2 (BA.4/BA.5) Spike RBD Protein (His & AVI Tag), Biotinylated

Purity

>95% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.

Pricing

$490/0.02 mg $955/2x0.02 mg $1,400/3x0.02 mg $1,815/4x0.02 mg $2,015/5x0.02 mg

What Are Active Proteins?

Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).

If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.

Key Applications of Active Proteins

1. Scientific Research

• Aid in the study of how proteins function in the body


• Aid in understanding various disease processes

2. Drug Development

• Powerful tools to investigate how potential drugs interact with specific proteins


• Ideal for identifying drug targets

3. Cell Culture

• Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)


• Can be used to promote cellular development into specific types (differentiation)

4. Diagnostics

• Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)


• Note: All products are strictly for research-use only (RUO).

5. Therapeutics

• Some active proteins are used directly as treatments (e.g., insulin, enzymes)


• Note: All products are strictly for research-use only (RUO).

6. Vaccine Development

• Used to create or test vaccines by mimicking parts of viruses or bacteria

7. Biochemical Assays

• They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests

Why Buy Active Proteins from AAA Biotech?

• High biological activity – Verified to perform as expected or indicated on datasheet


• Strict quality control – We are confident in our active proteins’ reliability and consistency


• High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components


• Freeze-dried for stability – Long shelf life and straightforward storage


• Mostly tag-free – Closer to natural/native protein form

FAQ

1. What are active proteins used for in research?

Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.

2. How are AAA Biotech's active proteins validated?

AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.

3. Are these proteins tested for biological activity?

Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.