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AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 750-800 of 2567 product results
Bioactivity
Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3, Active Protein (Cat# AAA177935)
Full Name
Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3 (C-Fc)
Gene Names
SIGLEC15; CD33L3; HsT1361; SIGLEC-15
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Bioactivity
IL-36 Receptor Antagonist Protein/IL-36RN/IL-1F5, Active Protein (Cat# AAA177938)
Full Name
Recombinant Human IL-36 Receptor Antagonist Protein/IL-36RN/IL-1F5
Gene Names
IL36RN; FIL1; FIL1D; IL1F5; IL1L1; PSORP; IL1HY1; IL1RP3; IL36RA; IL-36Ra; PSORS14; FIL1(DELTA)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Bioactivity
Siglec-10 Biotinylated, Active Protein (Cat# AAA177959)
Full Name
Recombinant Human Siglec-10 (C-Fc-Avi) Biotinylated
Gene Names
SIGLEC10; SLG2; PRO940; SIGLEC-10
Purity
>95% as determined by reducing SDS-PAGE
Pricing
SDS-PAGE
IL13RA2 / CD213A2, Active Protein (Cat# AAA173596)
Full Name
Recombinant Mouse IL13RA2 / CD213A2 Protein (His tag)
Gene Names
Il13ra2; CD213a2; IL-13R-alpha-2
Purity
> 98% as determined by SDS-PAGE
Pricing
SDS-PAGE
DAPK1 / DAP Kinase 1, Active Protein (Cat# AAA173507)
Full Name
Recombinant Human DAPK1 / DAP Kinase 1 Protein (aa 1-363, His & GST tag)
Gene Names
DAPK1; DAPK
Purity
(78.5 + 12.2%) as determined by SDS-PAGE
Pricing
Bioactivity
B-Cell Receptor CD22 (CD22), Active Protein (Cat# AAA243725)
Full Name
Recombinant Human B-Cell Receptor CD22 (CD22), Partial (Active)
Gene Names
CD22; SIGLEC2; SIGLEC-2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Bioactivity
Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17), Active Protein (Cat# AAA243734)
Full Name
Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17), Partial (Active)
Gene Names
TNFRSF17; BCM; BCMA; CD269; TNFRSF13A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Application Data
(Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells. The ED50 for this effect is 2.5-10 ug/mL.)
BMPR1A/ALK-3, Active Protein (Cat# AAA257883)
Full Name
BMPR1A/ALK-3 Protein, Human, Recombinant (His Tag)
Gene Names
BMPR1A; ALK3; SKR5; CD292; ACVRLK3; 10q23del
Purity
>85% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit FGF-acidic (aFGF/FGF1) dependent proliferation of Balb/C 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.5-2.5 ng/ml.)
FGFR2, Active Protein (Cat# AAA257933)
Full Name
FGFR2 Protein, Human, Recombinant (His & hFc Tag)
Gene Names
FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
Purity
>90% as determined by SDS-PAGE
Pricing
SDS-PAGE
Hemopexin, Active Protein (Cat# AAA257938)
Full Name
Hemopexin Protein, Human, Recombinant (His Tag)
Gene Names
HPX; HX
Purity
>96% as determined by SDS-PAGE
Pricing
Application Data
Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF), Active Protein (Cat# AAA146598)
Full Name
Active Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF)
Gene Names
CSF2; GMCSF
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
Interferon Gamma (IFNg), Active Protein (Cat# AAA146601)
Full Name
Active Interferon Gamma (IFNg)
Gene Names
IFNG; IFG; IFI
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
Insulin Like Growth Factor 1 (IGF1), Active Protein (Cat# AAA146604)
Full Name
Active Insulin Like Growth Factor 1 (IGF1)
Gene Names
IGF1; MGF; IGFI; IGF-I
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
Interleukin 6 (IL6), Active Protein (Cat# AAA146610)
Full Name
Active Interleukin 6 (IL6)
Gene Names
Il6; Il-6
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
Tumor Necrosis Factor Alpha (TNFa), Active Protein (Cat# AAA146615)
Full Name
Active Tumor Necrosis Factor Alpha (TNFa)
Gene Names
Tnf; DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
Tumor Necrosis Factor Beta (TNFb), Active Protein (Cat# AAA146616)
Full Name
Active Tumor Necrosis Factor Beta (TNFb)
Gene Names
LTA; LT; TNFB; TNFSF1; TNLG1E
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
Osteopontin (OPN), Active Protein (Cat# AAA146622)
Full Name
Active Osteopontin (OPN)
Gene Names
SPP1; OPN; BNSP; BSPI; ETA-1
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
WB (Western Blot)
(Western BlotSample: Recombinant HRG, Human;Antibody: Rabbit Anti-Human HRG Ab)
Histidine Rich Glycoprotein (HRG), Active Protein (Cat# AAA146623)
Full Name
Active Histidine Rich Glycoprotein (HRG)
Gene Names
HRG; HPRG; HRGP; THPH11
Reactivity
Homo sapiens (Human)
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>98%
Pricing
WB (Western Blot)
(Figure 4. Western BlotSample: Recombinant LMTK3, Human;Antibody: Rabbit Anti-Human LMTK3 Ab)
Lemur Tyrosine Kinase 3 (LMTK3), Active Protein (Cat# AAA146624)
Full Name
Active Lemur Tyrosine Kinase 3 (LMTK3)
Gene Names
LMTK3; LMR3; TYKLM3; PPP1R101
Reactivity
Homo sapiens (Human)
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
Interleukin 15 (IL15), Active Protein (Cat# AAA148129)
Full Name
Active Interleukin 15 (IL15)
Gene Names
IL15; IL-15
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
Interleukin 16 (IL16), Active Protein (Cat# AAA148141)
Full Name
Active Interleukin 16 (IL16)
Gene Names
IL16; LCF; NIL16; PRIL16; prIL-16
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
Vascular Endothelial Growth Factor 121 (VEGF121), Active Protein (Cat# AAA148143)
Full Name
Active Vascular Endothelial Growth Factor 121 (VEGF121)
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
WB (Western Blot)
(Sample: Recombinant MMP9, Porcine; Antibody: Rabbit Anti-Porcine MMP9 Ab)
Matrix Metalloproteinase 9 (MMP9), Active Protein (Cat# AAA149237)
Full Name
Active Matrix Metalloproteinase 9 (MMP9)
Gene Names
MMP9; GELB; CLG4B; MMP-9; MANDP2
Reactivity
Sus scrofa; Porcine (Pig)
Applications
Activity Assay, Cell Culture
Purity
>94%
Pricing
SDS-PAGE
Interleukin 2 (IL2), Active Protein (Cat# AAA148221)
Full Name
Active Interleukin 2 (IL2)
Gene Names
IL2; IL-2; TCGF; lymphokine
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
(Figure. Cell proliferation of Jurkat cells after stimulated with IL1a.Interleukin 1 alpha (IL1) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. IL1 is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha. To test the effect of IL1a on cell proliferation, Jurkat cells were seeded into triplicate wells of 96-well plates at a density of 2,000 cells/well with 2% serum standard 1640 including various concentrations of recombinant human IL1a. After incubated for 96h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37. Proliferation of Jurkat cells after incubation with IL1a for 96h observed by inverted microscope was shown in Figure 1. Cell viability was assessed by CCK-8 (Cell Counting Kit-8) assay after incubation with recombinant IL1a for 96h. The result was shown in Figure 2. It was obvious that IL1a significantly increased cell viability of Jurkat cells.(A) Jurkat cells cultured in 1640, stimulated with 10ng/mL IL1a for 96h; (B) Unstimulated Jurkat cells cultured in1640 for 96h.)
Interleukin 1 Alpha, Active Protein (Cat# AAA150058)
Full Name
Active Interleukin 1 Alpha (IL1a)
Gene Names
IL1A; IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
SDS_PAGE
(Sample: Active recombinant SOD3, Human)
Superoxide Dismutase 3, Extracellular, Active Protein (Cat# AAA150072)
Full Name
Active Superoxide Dismutase 3, Extracellular (SOD3)
Gene Names
SOD3; EC-SOD
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Application Data
(IL-1 (Interleukin-1 beta) is a proinflammatory and immunoregulatory cytokine involved in a variety of cellular activities. It has been elucidated that IL-1 stimulation of cells activates MMP-9 (matrix metalloproteinases-9) secretion by the activation of the dual signalling pathways. Thus, a stimulation assay of IL-1 was conducted using 3T3 cell line, and the MMP-9 activity was detected through gel zymography. Briefly, 1×106 3T3 cells were cultured overnight in 5%DMEM, washed with serum-free medium and then stimulated with different concentrations of IL-1 for 20h, and cell lysates were collected to measure MMP-9 activity. Cell lysates samples were denatured by SDS loading buffer, electrophoresed through sodium dodecyl sulphate–polyacrylamide gel (SDS–PAGE; 10% gels) containing gelatin (1mg/mL) with nonreducing conditions. After renaturation, incubation and coomassiebrilliant blue (CBB)-stained, MMPs hydrolyzed gelatin nearby, indicated by the white binds on the gel. Result Increased MMP-9 activity in 3T3 cells due to the stimulation of IL-1 was shown in Figure 1.Figure. Activation of MMP-9 by IL-1.)
Interleukin 1 Beta, Active Protein (Cat# AAA150093)
Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
Il1b; Il-1b; IL-1beta
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
Application Data
(Figure. Cell proliferation of spleen cells after stimulated with GP39.)
Chitinase-3-like Protein 1, Active Protein (Cat# AAA150109)
Full Name
Active Chitinase-3-like Protein 1 (CHI3L1)
Gene Names
Chi3l1; Chil1; GP-39; CGP-39
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Bioactivity
(Wingless-type MMTV integration site family, member 16 is a protein that in humans is encoded by the WNT16 gene. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5 termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. Besides, Tubulin Beta 3 (TUBb3) has been identified as an interactor of WNT16, thus a binding ELISA assay was conducted to detect the interaction of recombinant human WNT16 and recombinant human TUBb3. Briefly, WNT16 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to TUBb3-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-WNT16 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of WNT16 and TUBb3 was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of WNT16 with TUBb3.)
Wingless Type MMTV Integration Site Family, Member 16, Active Protein (Cat# AAA150149)
Full Name
Active Wingless Type MMTV Integration Site Family, Member 16 (WNT16)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
CNTF, Active Protein (Cat# AAA214336)
Full Name
Recombinant Rat CNTF
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
TFF2, Active Protein (Cat# AAA214282)
Full Name
Recombinant Human TFF2
Gene Names
TFF2; SP; SML1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
GM-CSF (CSF2), Active Protein (Cat# AAA214310)
Full Name
Recombinant Mouse GM-CSF (CSF2)
Gene Names
Csf2; CSF; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
IL2, Active Protein (Cat# AAA214316)
Full Name
Recombinant Mouse IL2
Gene Names
Il2; Il-2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
LIX (CXCL5), Active Protein (Cat# AAA214332)
Full Name
Recombinant Mouse LIX (CXCL5)
Gene Names
Cxcl5; LIX; Cxcl6; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
FGF8, Active Protein (Cat# AAA214334)
Full Name
Recombinant Mouse FGF8
Gene Names
FGF8; HH6; AIGF; KAL6; FGF-8; HBGF-8
Purity
>95% as determined by SDS-PAGE
Pricing
Bioactivity
(Galectin-12 is a member of a family of mammalian lectins known as galectins. The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities. Galectin-12 is predominantly expressed in adipose tissue and detected also in macrophages and other leukocytes. It plays an important role in cell-cell adhesion, cell-matrix interactions, macrophage activation, angiogenesis, metastasis, apoptosis. In this case, we chose rabbit erythrocyte (RaE) to assay its ability of agglutination. A general procedure for hemagglutination assay (or haemagglutination assay; HA) is as follows, two-fold dilute the recombinant Hu GAL12 with 0.9% sodium chloride injection, add 50uL a serial dilution of GAL12 to each well of a U or V-bottom shaped 96-well microtiter plate. The final well serves as a negative control with no GAL12, replace with 50uL 0.9% sodium chloride injection. Then add 50uL 1% rabbit erythrocyte to each well and mixed gently. The plate is incubated for 3 hours at room temperature. The results are shown in Figure 1. It was obvious that the minimal effective concentration of GAL12 is 0.781 ug/mL.)
Galectin 12 (GAL12), Active Protein (Cat# AAA152174)
Full Name
Active Galectin 12 (GAL12)
Gene Names
LGALS12; GAL12; GRIP1
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(Galectin 8 (GAL8), also known as prostate carcinoma tumor antigen 1 (PCTA1) in human, is a tandem repeat-type galectin. is a member of the lectin family, of which 14 mammalian galectins have been identified. It is also a member of the beta-galactoside-binding protein family that plays an important role in cell-cell adhesion, cell-matrix interactions, macrophage activation, angiogenesis, metastasis, apoptosis. In this case, we chose rabbit erythrocyte (RaE) to assay its ability of agglutination. A general procedure for hemagglutination assay (or haemagglutination assay; HA) is as follows, two-fold dilute the recombinant Bovine GAL8 with 0.9% sodium chloride injection, add 50uL a serial dilution of GAL8 to each well of a U or V-bottom shaped 96-well microtiter plate. The final well serves as a negative control with no GAL8, replace with 50uL 0.9% sodium chloride injection. Then add 50uL 1% rabbit erythrocyte to each well and mixed gently. The plate is incubated for 3 hours at room temperature. The results are shown in Figure 1. It was obvious that the minimal effective concentration of GAL8 is 0.781 ug/mL.)
Galectin 8 (GAL8), Active Protein (Cat# AAA152177)
Full Name
Active Galectin 8 (GAL8)
Gene Names
LGALS8; galectin-8
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(carboxylesterase 1 (CES1) also known as Liver carboxylesterase 1 is a serine esterase and member of a large multigene carboxylesterase family. The protein Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Thus, the recombinant human CES1 activity was measured by its ability to hydrolyze 4-Nitrophenyl acetate (4-NPA) to 4-Nitrophenol. The reaction was performed in 50 mM Tris, pH 7.5(Assay Buffer), initiated by addition 50 uL of various concentrations of CES1 (dilute by Assay Buffer) to 50 uL of 2 mM Substrate 4-NPA(100 mM stock in Acetone, dilute by deionized water). Incubated at 37 degree C for 10min, then read at a wavelength of 400 nm.)
Carboxylesterase 1 (CES1), Active Protein (Cat# AAA152179)
Full Name
Active Carboxylesterase 1 (CES1)
Gene Names
CES1; CEH; REH; TGH; ACAT; CE-1; CES2; HMSE; SES1; HMSE1; PCE-1; hCE-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(FAS (Tumor necrosis factor receptor superfamily member 6) belongs to the tumor necrosis factor receptor superfamily. FAS contains a death domain, which has been shown to play a central role in the physiological regulation of programmed cell death. A bindi)
Factor Related Apoptosis (FAS), Active Protein (Cat# AAA152950)
Full Name
Active Factor Related Apoptosis (FAS)
Gene Names
FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. Inhibition of A549 cells proliferation after stimulated with recombinant mouse IFN-alpha.)
Interferon Alpha (IFNa), Active Protein (Cat# AAA152953)
Full Name
Active Interferon Alpha (IFNa)
Gene Names
Ifna1; Ifa1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. Cell proliferation of TF-1 cells after stimulated with GM-CSF.)
Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF), Active Protein (Cat# AAA152960)
Full Name
Active Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF)
Gene Names
Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. The dose-effect curve of IL-3 on TF-1 cells)
Interleukin 3 (IL3), Active Protein (Cat# AAA152969)
Full Name
Active Interleukin 3 (IL3)
Gene Names
Il3; BPA; PSF; HCGF; Il-3; MCGF; Csfmu
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.Thus, chemotaxis assay used 24-well microchemotaxis syste)
Interleukin 8 (IL8), Active Protein (Cat# AAA152973)
Full Name
Active Interleukin 8 (IL8)
Gene Names
CXCL8; IL8
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Monocyte Chemotactic Protein 1 (MCP1), also known as C-C motif chemokine 2(CCL2), is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and basophils. Rat CCL2 is secreted as a 14 kDa glycoprotein monomer but noncov)
Monocyte Chemotactic Protein 1 (MCP1), Active Protein (Cat# AAA152976)
Full Name
Active Monocyte Chemotactic Protein 1 (MCP1)
Gene Names
Ccl2; MCP-1; Scya2; Sigje
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(Extracellular superoxide dismutase [Cu-Zn] is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide r)
Superoxide Dismutase 3, Extracellular (SOD3), Active Protein (Cat# AAA152980)
Full Name
Active Superoxide Dismutase 3, Extracellular (SOD3)
Gene Names
Sod3; EC-SOD; AI314465
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. Inhibition of A549 cells proliferation after stimulated with TNFalpha)
Tumor Necrosis Factor Alpha (TNFa), Active Protein (Cat# AAA152989)
Full Name
Active Tumor Necrosis Factor Alpha (TNFa)
Gene Names
TNF; TNF-alpha
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFalpha, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. The primary role of TNF)
Tumor Necrosis Factor Alpha (TNFa), Active Protein (Cat# AAA152994)
Full Name
Active Tumor Necrosis Factor Alpha (TNFa)
Gene Names
TNF; TNF-ALPHA
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Thrombopoietin (TPO) is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis.TPO can promote platelet production, aggregation, ECM adhesion, and activation. It is principally produced in t)
Thrombopoietin (TPO), Active Protein (Cat# AAA152997)
Full Name
Active Thrombopoietin (TPO)
Gene Names
Thpo; Ml; Tpo; Mgdf; Tpo1; Tpo2; Tpo3; Tpo4; Mpllg
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Plasminogen Activator, Urokinase Receptor (uPAR) is the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasmi)
Plasminogen Activator, Urokinase Receptor (uPAR), Active Protein (Cat# AAA152999)
Full Name
Active Plasminogen Activator, Urokinase Receptor (uPAR)
Gene Names
Plaur; Par; uPAR; Plaur3; uPAR-2; uPAR-3
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. Cell apoptosis of A549 cells after stimulated with recombinant dog IFNb.)
Interferon Beta (IFNb), Active Protein (Cat# AAA153002)
Full Name
Active Interferon Beta (IFNb)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.