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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 550-600 of 2567 product results


product-image-AAA153006_BIOACTIVITY11.jpg Bioactivity (Figure 2. Cell apoptosis of A549 cells after stimulated with recombinant rat IFNb.)

Interferon Beta (IFNb), Active Protein (Cat# AAA153006)

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Full Name
Active Interferon Beta (IFNb)
Gene Names
Ifnb1; Ifnb
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153092_BIOACTIVITY13.jpg Bioactivity (Interleukin 3 receptor alpha (IL3Ra), also known as CD123 (Cluster of Differentiation 123), is a subunit of the functional high-affinity mouse IL-3 receptor which is a heterodimer. The alpha subunit alone binds IL-3 with low affinity. The beta subunit doe)

Interleukin 3 Receptor Alpha (IL3Ra), Active Protein (Cat# AAA153092)

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Full Name
Active Interleukin 3 Receptor Alpha (IL3Ra)
Gene Names
Il3ra; CD123; SUT-1; CDw123
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153098_BIOACTIVITY13.png Bioactivity (Extracellular matrix metalloproteinase (MMP) inducer (EMMPRIN), also known as basigin and CD147, is a 4466 kDa, variably N and Oglycosylated, type I transmembrane protein that belongs to the immunoglobulin superfamily. EMMPRIN is 269 amino acids (aa) in l)

Cluster Of Differentiation 147 (CD147), Active Protein (Cat# AAA153098)

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Full Name
Active Cluster Of Differentiation 147 (CD147)
Gene Names
Bsg; HT-7; CD147; EMMPRIN; AI115436; AI325119
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153104_BIOACTIVITY13.jpg Bioactivity (Interleukin-6 receptor (IL-6R) is a receptor for IL-6, belonging to the type I cytokine receptor family, subfamily 3. IL-6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. IL-6)

Interleukin 6 Receptor (IL6R), Active Protein (Cat# AAA153104)

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Full Name
Active Interleukin 6 Receptor (IL6R)
Gene Names
IL6R; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153116_BIOACTIVITY13.jpg Bioactivity (Catalase (CAT) is an antioxidant enzyme present in all aerobic organisms. It is known to catalyze H2O2 into water and oxygen in an energy-efficient manner in the cells exposed to environmental stress. H2O2 will have specific absorbance at 240 nm . when wi)

Catalase (CAT), Active Protein (Cat# AAA153116)

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Full Name
Active Catalase (CAT)
Gene Names
Cat; Cas1; Cs-1; Cas-1; 2210418N07
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153133_BIOACTIVITY11.jpg Bioactivity (One unit of enzyme activity is defined as the 1ug of enzyme required to convert 1pmol of 4-Nitrophenyl acetate to 4-Nitrophenol in 1min at 37 degree C. The specific activity of recombinant human CES3 is 700 pmol/min/ug.)

Carboxylesterase 3 (CES3), Active Protein (Cat# AAA153133)

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Full Name
Active Carboxylesterase 3 (CES3)
Gene Names
CES3; ES31
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153134_BIOACTIVITY11.jpg Bioactivity (One unit of enzyme activity is defined as the 1ug of enzyme required to convert 1pmol of 4-Nitrophenyl acetate to 4-Nitrophenol in 1min at 37 degree C. The specific activity of recombinant mouse CES3 is 900 pmol/min/ug.)

Carboxylesterase 3 (CES3), Active Protein (Cat# AAA153134)

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Full Name
Active Carboxylesterase 3 (CES3)
Gene Names
Ces1d; TGH; Ces3
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153014_BIOACTIVITY11.jpg Bioactivity (Figure 2. The hemagglutination assay of GAL2 in V- bottom shaped 96-well microtiter plate.)

Galectin 2 (GAL2), Active Protein (Cat# AAA153014)

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Full Name
Active Galectin 2 (GAL2)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153033_BIOACTIVITY13.jpg Bioactivity (Type I collagen is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. It is a heterotrimer that consists of two alpha 1 chains and one alpha 2 chain, although homotrimers consisting of three iden)

Collagen Type I Alpha 1 (COL1a1), Active Protein (Cat# AAA153033)

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Full Name
Active Collagen Type I Alpha 1 (COL1a1)
Gene Names
COL1A1; OI4
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153039_BIOACTIVITY13.jpg Bioactivity (Basic fibroblast growth factor (FGF2), also known as bFGF, FGF-beta is a member of a large family of structurally related heparin-binding proteins (the FGFs) involved in the regulation of cell proliferation, growth and differentiation. It involved in many)

Fibroblast Growth Factor 2, Basic (FGF2), Active Protein (Cat# AAA153039)

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Full Name
Active Fibroblast Growth Factor 2, Basic (FGF2)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153045_BIOACTIVITY13.jpg Bioactivity (Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)

Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153045)

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Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
IL-1B; IL1B
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153054_BIOACTIVITY13.jpg Bioactivity (Fibroblast growth factor 23 or FGF23 is a member of the fibroblast growth factor (FGF) family which is responsible for phosphate and vitamin D metabolism. The main function of FGF23 seems to be regulation of phosphate concentration in plasma. FGF23 decrea)

Fibroblast Growth Factor 23 (FGF23), Active Protein (Cat# AAA153054)

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Full Name
Active Fibroblast Growth Factor 23 (FGF23)
Gene Names
FGF23; ADHR; FGFN; HYPF; HPDR2; PHPTC
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153066_BIOACTIVITY13.jpg Bioactivity (Osteopontin (OPN), a multifunctional phosphorylated glycoprotein, plays an important role in neutrophil recruitment and was found to induce the expression of proinflammatory chemokines including MCP-1 and MIP-1beta which promote migration and recruitment)

Osteopontin (OPN), Active Protein (Cat# AAA153066)

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Full Name
Active Osteopontin (OPN)
Gene Names
Spp1; OP; 2AR; Bsp; Eta; Opn; Ric; BNSP; BSPI; Opnl; Apl-1; ETA-1; Spp-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153072_BIOACTIVITY13.jpg Bioactivity (Motility Related Protein (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. It can enable ATPase-coupled inorganic anion transmembrane transporter activity. Involved in anion transmembrane transport; renal tubular secretion)

Motility Related Protein (MRP1), Active Protein (Cat# AAA153072)

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Full Name
Active Motility Related Protein (MRP1)
Gene Names
CD9; MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29
Applications
Activity Assay, Cell Culture
Purity
Greater than 80% by SDS-PAGE
Pricing
product-image-AAA177964_BIOACTIVITY13.jpg Bioactivity

Tumor-associated Calcium Signal Transducer 2/TROP-2, Active Protein (Cat# AAA177964)

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Full Name
Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (248AA, C-Fc)
Gene Names
TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA173576_SDS_PAGE15.jpg SDS-PAGE

Carbonic Anhydrase IX / CA9, Active Protein (Cat# AAA173576)

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Full Name
Recombinant Human Carbonic Anhydrase IX / CA9 Protein (His tag)
Gene Names
CA9; MN; CAIX
Purity
> 95 % as determined by SDS-PAGE
Pricing
product-image-AAA173585_SDS_PAGE15.jpg SDS-PAGE

IL1R1 / CD121a, Active Protein (Cat# AAA173585)

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Full Name
Recombinant Mouse IL1R1 / CD121a Protein (His tag)
Gene Names
Il1r1; IL-iR; CD121a; CD121b; IL-1R1; Il1r-1
Purity
> 95 % as determined by SDS-PAGE
Pricing
product-image-AAA114580_SDS_PAGE15.jpg SDS-PAGE

Interferon alpha-2, Active Protein (Cat# AAA114580)

No reviews yet
Full Name
Recombinant Human Interferon alpha-2
Gene Names
IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA257945_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized Human Ephrin-A1 His at 2 ug/ml (100 ul/well) can bind Human EphA1 hFc, the EC50 of Human EphA1 hFc is 8.0-48.0 ng/mL.)

Ephrin-A1, Active Protein (Cat# AAA257945)

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Full Name
Ephrin-A1 Protein, Human, Recombinant (His Tag)
Gene Names
EFNA1; B61; EFL1; ECKLG; EPLG1; LERK1; LERK-1; TNFAIP4
Purity
>97% as determined by SDS-PAGE
Pricing
product-image-AAA258101_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD(Y453F)-His (40592-V08H80), the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD(Y453F)-His (40592-V08H80) is 5-20 ng/mL.)

COVID 19 Spike RBD(Y453F)-His Coronavirus, Active Protein (Cat# AAA258101)

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Full Name
SARS-CoV-2 (2019-nCoV) Spike RBD(Y453F)-His Recombinant Protein
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA258591_AD11.png Application Data (Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 (BA.2.12.1) Spike RBD Protein(His&AVI Tag), Biotinylated(Cat: AAA258591), the EC50 is 4.5-13 ng/mL.)

COVID 19 (BA.2.12.1) Spike RBD Coronavirus, Active Protein (Cat# AAA258591)

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Full Name
SARS-CoV-2 (BA.2.12.1) Spike RBD Protein (His & AVI Tag), Biotinylated
Purity
>95% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
Pricing
product-image-AAA214257_AD13.png Application Data

IL22, Active Protein (Cat# AAA214257)

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Full Name
Recombinant Human IL22
Gene Names
IL22; TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA214263_AD13.png Application Data

GMFB, Active Protein (Cat# AAA214263)

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Full Name
Recombinant Human GMFB
Gene Names
GMFB; GMF
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA150049_AD8.png Bioactivity (Figure 2. Inhibition of A549 cells proliferation after stimulated with IFN-.)

Interferon Alpha, Active Protein (Cat# AAA150049)

No reviews yet
Full Name
Active Interferon Alpha (IFNa)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
product-image-AAA152021_SDS_PAGE10.jpg SDS_PAGE

Perforin 1 (PRF1), Active Protein (Cat# AAA152021)

No reviews yet
Full Name
Active Perforin 1 (PRF1)
Gene Names
PRF1; P1; PFP; FLH2; PFN1; HPLH2
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>80%
Pricing
product-image-AAA146599_AD11.jpg Application Data

Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF), Active Protein (Cat# AAA146599)

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Full Name
Active Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF)
Gene Names
Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
product-image-AAA146602_AD8.jpg Application Data

Interferon Gamma (IFNg), Active Protein (Cat# AAA146602)

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Full Name
Active Interferon Gamma (IFNg)
Gene Names
Ifng; Ifg; IFN-g
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146611_AD10.jpg Application Data

Macrophage Inflammatory Protein 1 Alpha (MIP1a), Active Protein (Cat# AAA146611)

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Full Name
Active Macrophage Inflammatory Protein 1 Alpha (MIP1a)
Gene Names
CCL3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146612_SDS_PAGE7.jpg SDS-PAGE

Matrix Metalloproteinase 2 (MMP2), Active Protein (Cat# AAA146612)

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Full Name
Active Matrix Metalloproteinase 2 (MMP2)
Gene Names
MMP2; CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>98%
Pricing
product-image-AAA146619_AD8.jpg Application Data

Insulin (INS), Active Protein (Cat# AAA146619)

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Full Name
Active Insulin (INS)
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA150971_SEQUENCE10.jpg Sequence

Colony Stimulating Factor 1, Macrophage (MCSF), Active Protein (Cat# AAA150971)

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Full Name
Active Colony Stimulating Factor 1, Macrophage (MCSF)
Gene Names
Csf1; op; Csfm; MCSF; C87615
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA150974_SEQUENCE10.jpg Sequence

Sex Hormone Binding Globulin (SHBG), Active Protein (Cat# AAA150974)

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Full Name
Active Sex Hormone Binding Globulin (SHBG)
Gene Names
SHBG; ABP; SBP; TEBG
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA148123_AD11.jpg Application Data

Interleukin 17 Receptor C (IL17RC), Active Protein (Cat# AAA148123)

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Full Name
Active Interleukin 17 Receptor C (IL17RC)
Gene Names
IL17RC; CANDF9; IL17RL; IL17-RL
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA148128_AD8.jpg Application Data

V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC), Active Protein (Cat# AAA148128)

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Full Name
Active V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC)
Gene Names
MYC; MRTL; MYCC; c-Myc; bHLHe39
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA148148_AD11.jpg Application Data

Neuraminidase (NEU), Active Protein (Cat# AAA148148)

No reviews yet
Full Name
Active Neuraminidase (NEU)
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
product-image-AAA148250_BIOACTIVITY13.jpg Bioactivity (Figure 2. Cell proliferation of 3T3 cells after stimulated with AGE.)

Advanced Glycation End Product (AGE), Active Protein (Cat# AAA148250)

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Full Name
Active Advanced Glycation End Product (AGE)
Applications
Activity Assay, Cell Culture
Purity
Purity: >90% as determined by SDS-PAGE.
Purification Methods: Salt co-precipitation and ionic-Exchange chromatography.
Pricing
product-image-AAA150067_AD11.png Application Data (Figure. The chemotactic effect of recombinant human MIP1-on Jurkat cells.)

Macrophage Inflammatory Protein 1 Beta, Active Protein (Cat# AAA150067)

No reviews yet
Full Name
Active Macrophage Inflammatory Protein 1 Beta (MIP1b)
Gene Names
CCL4; ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
product-image-AAA150076_BIOACTIVITY10.jpg Bioactivity (Figure. The binding activity of TIMP3 with MMP2.Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) is an protein belongs to the tissue inhibitor of metalloproteinases family. They are inhibitors of the matrix metalloproteinases. TIMP-3 is the only member of the TIMP family which is found exclusively in the extracellular matrix (ECM). It is regulated in a cell cycle-dependent fashion in certain cell types and may serve as a marker for terminal differentiation. Besides, Matrix Metalloproteinase 2 (MMP2) has been identified as an interactor of TIMP3, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse TIMP3 and recombinant mouse MMP2. Briefly, TIMP3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100ul were then transferred to MMP2-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-TIMP3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of TIMP3 and MMP2 was shown in Figure 1, and this effect was in a dose dependent manner.)

Tissue Inhibitors Of Metalloproteinase 3, Active Protein (Cat# AAA150076)

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Full Name
Active Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
Gene Names
Timp3; Timp-3
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
product-image-AAA150094_BIOACTIVITY10.jpg Bioactivity (Figure. The binding activity of IL1b with IL1R1.)

Interleukin 1 Beta, Active Protein (Cat# AAA150094)

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Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
Il1b; IL-1F2
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150095_WB13.png WB (Western Blot) (Western Blot Sample: Recombinant PIIINP, Human;Antibody: Rabbit Anti-Human PIIINP Ab)

Procollagen III N-Terminal Propeptide, Active Protein (Cat# AAA150095)

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Full Name
Active Procollagen III N-Terminal Propeptide (PIIINP)
Gene Names
COL3A1; EDS4A; EDSVASC; PMGEDSV
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>98%
Pricing
product-image-AAA150112_BIOACTIVITY13.jpg Bioactivity (Myostatin (MSTN) also known as growth differentiation factor 8 (GDF-8) is a member of the TGF beta protein family. Myostatin is a secreted growth differentiation factor that produced and released by myocytes. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Besides, Bone Morphogenetic Protein 1 (BMP1) has been identified as an interactor of MSTN, thus a binding ELISA assay was conducted to detect the interaction of recombinant human MSTN and recombinant human BMP1. Briefly, MSTN were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to BMP1-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-MSTN pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of MSTN and BMP1 was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of MSTN with BMP1.)

Myostatin, Active Protein (Cat# AAA150112)

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Full Name
Active Myostatin (MSTN)
Gene Names
MSTN; GDF8; MSLHP
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150560_SDS_PAGE11.jpg SDS-PAGE (Figure. SDS-PAGE)

Fibroblast Growth Factor 10 (FGF10), Active Protein (Cat# AAA150560)

No reviews yet
Full Name
Active Fibroblast Growth Factor 10 (FGF10)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
product-image-AAA150147_AD11.jpg Application Data (Semaphorin-3F (SEMA3F) is a member of semaphorins family. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues. Semaphorins not only guide axons in development, but also have major roles in immune function (classes 4, 6, and 7) and the development of bones. Class 3 semaphorins are one of the most versatile semaphorin classes, in which Sema3a is the most studied. Besides, SEMA3F is deleted or downregulated in many metastatic tumors. To test the effect of SEMA3F on inhibit cell proliferation, human lung carcinoma cells A549 were seeded into triplicate wells of 96-well plates at a density of 5,000 cells/well and allowed to attach, replaced with serum-free overnight, then the medium was replaced with 2% serum standard DMEM prior to the addition of various concentrations of recombinant human SEMA3F. After incubated for 48h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37. Proliferation of A549 cells after incubation with SEMA3F for 48h observed by inverted microscope was shown in Figure 1. Cell viability was assessed by CCK-8 assay after incubation with recombinant SEMA3F for 48h. The result was shown in Figure 2. It was obvious that SEMA3F significantly increased cell viability of A549 cells. (A) A549 cells cultured in DMEM, stimulated with 100ng/mL SEMA3F for 48h; (B) Unstimulated A549 cells cultured in DMEM for 48h.Figure. Cell proliferation of A549 cells inhibtion by stimulating with SEMA3F.)

Semaphorin 3F, Active Protein (Cat# AAA150147)

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Full Name
Active Semaphorin 3F (SEMA3F)
Gene Names
SEMA3F; SEMA4; SEMAK; SEMA-IV
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA152181_BIOACTIVITY13.png Bioactivity (Perforin 1 (PRF1) is a pore forming cytolytic protein found in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Upon degranulation, perforin binds to the target cell's plasma membrane, and oligomerises in a Ca2 dependent manner to form pores on the target cell. The pore formed allows for the passive diffusion of a family of pro-apoptotic proteases, known as the granzymes, into the target cell. The activity of recombinant PRF1 was measured by lysis of erythrocytes using a hemolysis assay. A general procedure is as fllows: two-fold dilute the recombinant mouse PRF1 with 0.9% NaCl, add 50ul a serial dilution of PRF1, 10ul 0.1M CaCl2 to each well, then add 50ul 0.25% rabbit erythrocyte (RaE) to each well and mixed gently. Add 50ul 0.9% NaCl to replace PRF1 in control wells. The plate is incubated for 20 hours at 37 degree C, 5% CO2. The results are shown in Figure 1. It was obvious that the minimal effective concentration of PRF1 is 5ug/ml.)

Perforin 1 (PRF1), Active Protein (Cat# AAA152181)

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Full Name
Active Perforin 1 (PRF1)
Gene Names
Prf1; Pfn; Pfp; Prf-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA244030_BIOACTIVITY13.jpg Bioactivity

Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B), Active Protein (Cat# AAA244030)

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Full Name
Recombinant Human Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B), partial
Gene Names
TNFRSF1B; p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA243728_BIOACTIVITY13.jpg Bioactivity

Ephrin-A5 (EFNA5), Active Protein (Cat# AAA243728)

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Full Name
Recombinant Human Ephrin-A5 (EFNA5) (Active)
Gene Names
EFNA5; AF1; EFL5; RAGS; EPLG7; GLC1M; LERK7
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA153090_BIOACTIVITY13.jpg Bioactivity (Interleukin 3 receptor alpha (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a subunit of the functional high-affinity human IL-3 receptor which is a heterodimer. The alpha subunit alone binds IL-3 with low affinity. The beta subunit doe)

Interleukin 3 Receptor Alpha (IL3Ra), Active Protein (Cat# AAA153090)

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Full Name
Active Interleukin 3 Receptor Alpha (IL3Ra)
Gene Names
IL3RA; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153093_SDS_PAGE8.jpg SDS-PAGE (Sample: Active recombinant GNLY, Human)

Granulysin (GNLY), Active Protein (Cat# AAA153093)

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Full Name
Active Granulysin (GNLY)
Gene Names
GNLY; 519; LAG2; NKG5; LAG-2; D2S69E; TLA519
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>80%
Pricing
product-image-AAA153095_BIOACTIVITY13.jpg Bioactivity (Extracellular matrix metalloproteinase (MMP) inducer (EMMPRIN), also known as basigin and CD147, is a 4466 kDa, variably N and Oglycosylated, type I transmembrane protein that belongs to the immunoglobulin superfamily. Human EMMPRIN is 269 amino acids (aa)

Cluster Of Differentiation 147 (CD147), Active Protein (Cat# AAA153095)

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Full Name
Active Cluster Of Differentiation 147 (CD147)
Gene Names
BSG; M6; OK; 5F7; TCSF; CD147; EMMPRIN
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153105_BIOACTIVITY13.jpg Bioactivity (Sonic Hedgehog (Shh) is expressed in embryonic tissues that are critical for the patterning of the developing central nervous system, somite, and limb. It is also involved in whisker, hair, foregut, tooth, and bone development. Shh regulates neural and he)

Hedgehog Homolog, Sonic (SHH), Active Protein (Cat# AAA153105)

No reviews yet
Full Name
Active Hedgehog Homolog, Sonic (SHH)
Gene Names
SHH; TPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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