Osteocrin Active Protein | OSTN active protein
Recombinant Human Osteocrin protein
Gene Names
OSTN; MUSCLIN
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
Osteocrin; N/A; Recombinant Human Osteocrin protein; MUSCLIN; OSTN; OSTN active protein
Host
HEK293
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid in. Phosphate-Buffered Saline (pH7.4) containing 10% glycerol
Concentration
0.5mg/ml (determined by Bradford assay) (varies by lot)
Sequence Positions
28-133aa
Sequence
Val 19
VDVTTTEAFD SGVIDVQSTP TVREEKSATD LTAKLLLLDE LVSLENDVIE TKKKRSFSGF GSPLDRLSAG SVDHKGKQRK VVDHPKRRFG IPMDRIGRNR LSNSRG
VDVTTTEAFD SGVIDVQSTP TVREEKSATD LTAKLLLLDE LVSLENDVIE TKKKRSFSGF GSPLDRLSAG SVDHKGKQRK VVDHPKRRFG IPMDRIGRNR LSNSRG
Applicable Applications for OSTN active protein
Bioactivity, SDS-PAGE
Species
Human
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Tag
His-Tag
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Related Product Information for OSTN active protein
Osteocrin, also known as Musclin, shows a well conserved homology with members of the natriuretic peptide (NP) family. It is a secreted protein that is expressed in muscle and bone. Based on similarities with NPs, Osteocrin could interact with the NP clearance receptors, importantly increasing CNP which has been shown to stimulate endochondral ossification and elongate bones. It is represents a novel, unique vitamin D-regulated bone-specific. Recombinant human Osteocrin, fused to His-tag at C-terminus, was expressed in HEK 293 cell and purified by using conventional chromatography techniques.
References
Thomas, G., et al, (2003) J. Biol. Chem. 278:50563-50571.
Nishizawa H., et al, (2004) J Biol Chem. 279:19391-19395.
Pierre Moffatt., et al, (2007) J Biol Chem. 282:36454-36462.
Nishizawa H., et al, (2004) J Biol Chem. 279:19391-19395.
Pierre Moffatt., et al, (2007) J Biol Chem. 282:36454-36462.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,722 Da
NCBI Official Full Name
osteocrin
NCBI Official Synonym Full Names
osteocrin
NCBI Official Symbol
OSTN
NCBI Official Synonym Symbols
MUSCLIN
NCBI Protein Information
osteocrin
UniProt Protein Name
Osteocrin
UniProt Gene Name
OSTN
UniProt Entry Name
OSTN_HUMAN
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Product Notes
The OSTN ostn (Catalog #AAA49001) is an Active Protein produced from HEK293 and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 28-133aa. AAA Biotech's Osteocrin can be used in a range of immunoassay formats including, but not limited to, Bioactivity, SDS-PAGE. Researchers should empirically determine the suitability of the OSTN ostn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Val 19 VDVT TTEAFD SGVIDVQSTP TVREEKSATD LTAKLLLLDE LVSLENDVIE TKKKRSFSGF GSPLDRLSAG SVDHKGKQRK VVDHPKRRFG IPMDRIGRNR LSNSRGPrecautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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