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FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Raji cells with PRDM1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).)
Mouse anti-Human PRDM1 Monoclonal Antibody | anti-PRDM1 antibody
PRDM1 Antibody
Gene Names
PRDM1; BLIMP1; PRDI-BF1
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
PRDM1, Antibody; PRDM1 Antibody; B Lymphocyte Induced Maturation Protein 1 antibody; Beta interferon gene positive regulatory domain I binding factor antibody; Beta-interferon gene positive regulatory domain I-binding factor antibody; BLIMP-1 antibody; BLIMP1 antibody; Positive Regulatory Domain I Binding Factor 1 antibody; Positive regulatory domain I-binding factor 1 antibody; PR Domain Containing 1 antibody; PR domain containing 1 with ZNF domain antibody; PR domain containing 1 with ZNF domain isoform 2 antibody; PR domain containing protein 1 antibody; PR domain zinc finger protein 1 antibody; PR domain-containing protein 1 antibody; PRDI BF1 antibody; PRDI binding factor 1 antibody; PRDI-BF1 antibody; PRDI-binding factor 1 antibody; PRDM 1 antibody; Prdm1 antibody; PRDM1_HUMAN antibody; anti-PRDM1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
B6-F1
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-PRDM1 antibody
FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), WB (Western Blot)
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Raji cells with PRDM1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Raji cells with PRDM1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).)
ICC (Immunocytochemistry)
(ICC staining PRDM1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining PRDM1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
WB (Western Blot)
(Western blot analysis of PRDM1 on HEK293 (1) and PRDM1-hIgGFc transfected HEK293 (2) cell lysate using anti-PRDM1 antibody at 1/1, 000 dilution.)
WB (Western Blot)
(Western blot analysis of PRDM1 on HEK293 (1) and PRDM1-hIgGFc transfected HEK293 (2) cell lysate using anti-PRDM1 antibody at 1/1, 000 dilution.)
WB (Western Blot)
(Western blot analysis of PRDM1 on human PRDM1 recombinant protein using anti-PRDM1 antibody at 1/1, 000 dilution.)
WB (Western Blot)
(Western blot analysis of PRDM1 on human PRDM1 recombinant protein using anti-PRDM1 antibody at 1/1, 000 dilution.)
Related Product Information for anti-PRDM1 antibody
The development and differentiation of plasma cells, which are terminally differentiated B-cells, are induced by Blimp-1 (B lymphocyte-induced maturation protein, also designated PRDI-BF1). Blimp-1 is a transcriptional repressor that localizes to the nucleus and is considered a master regulator of terminal B-cell development. Alone, Blimp-1 is sufficient to trigger terminal B-cell differentiation. Blimp-1 upregulates the expression of syndecan-1 and J chain, represses IFN-b gene transcription and associates with HDAC to recruit it to DNA, thereby repressing c-myc. Blimp-1 is expressed during the late stages of B-cell differentiation in immunoglobulin-secreting plasma cells, as well as in long-lived, bone marrow plasma cells. The expression of Blimp-1 defines a checkpoint beyond which fully activated B cells proceed to the plasma cell stage, whereas immature and partially activated cells are eliminated.
Product Categories/Family for anti-PRDM1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
825
NCBI Official Full Name
PR domain zinc finger protein 1 isoform 1
NCBI Official Synonym Full Names
PR domain containing 1, with ZNF domain
NCBI Official Symbol
PRDM1
NCBI Official Synonym Symbols
BLIMP1; PRDI-BF1
NCBI Protein Information
PR domain zinc finger protein 1; BLIMP-1; PRDI-binding factor-1; B-lymphocyte-induced maturation protein 1; beta-interferon gene positive-regulatory domain I binding factor
UniProt Protein Name
PR domain zinc finger protein 1
UniProt Gene Name
PRDM1
UniProt Synonym Gene Names
BLIMP1; PRDI-BF1
UniProt Entry Name
PRDM1_HUMAN
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Product Notes
The PRDM1 prdm1 (Catalog #AAA312042) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PRDM1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PRDM1 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PRDM1 prdm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRDM1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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