Host
Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
I21/7
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
1163
Applicable Applications for anti-CD11a antibody
IP (Immunoprecipitation), FCM/FACS (Flow Cytometry)
Perservative Stabilisers
0.09% Sodium Azide
Preparation
Preparation
Immunogen
Whole BW5147 cells.
Buffer Solution
Buffer Solution
Target Species
Mouse
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-CD11a antibody
Rat anti Mouse CD11a antibody, clone I21/7 recognizes murine CD11a, a ~170-180kDa type I membrane glycoprotein, also known as the integrin alpha L subunit. CD11a is a member of the intergrin family of adhesion molecules. CD11a is expressed on all leucocytes and associates with CD18 to form a heterodimer at the cell surface. The CD11a/CD18 heterodimer binds to intercellular adhesion molecules (ICAM); ICAM1, ICAM-2 and ICAM-3 and is involved in cell-cell adhesion processes. Rat anti Mouse CD11a antibody, clone I21/7 is reported to block the cytolytic activity of cytotoxic T cell lines (Trowbridge and Omary 1981).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
128,328 Da
NCBI Official Full Name
Integrin alpha-L
NCBI Official Synonym Full Names
integrin alpha L
NCBI Official Symbol
Itgal
NCBI Official Synonym Symbols
Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A
NCBI Protein Information
integrin alpha-L; CD11 antigen-like family member A; alpha L integrin; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide
UniProt Protein Name
Integrin alpha-L
UniProt Gene Name
Itgal
UniProt Synonym Gene Names
Lfa-1; Ly-15; LFA-1A; Ly-15
UniProt Entry Name
ITAL_MOUSE
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Product Notes
The CD11a itgal (Catalog #AAA49250) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD11a can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD11a itgal for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD11a, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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