IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human small intestine tissue slide using ADSL Monoclonal Antibody at dilution of 1:500.)
Rabbit anti-Human ADSL Monoclonal Antibody | anti-ADSL antibody
Rabbit anti Human ADSL Monoclonal Antibody
Gene Names
ADSL; ASL; AMPS; ASASE
Reactivity
Human
Applications
Immunoprecipitation, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
ADSL, Antibody; Rabbit anti Human ADSL Monoclonal Antibody; Adenylosuccinate lyase, ADSL, ASL, Adenylosuccinase, ASase, AMPS; anti-ADSL antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
0.2 um filtered solution in PBS
Sequence Length
420
Applicable Applications for anti-ADSL antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant Human ADSL protein
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human small intestine tissue slide using ADSL Monoclonal Antibody at dilution of 1:500.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human small intestine tissue slide using ADSL Monoclonal Antibody at dilution of 1:500.)
WB (Western Blot)
(Western blot analysis of HepG2 cells using ASGR1 Monoclonal Antibody at dilution of 1:500.)
WB (Western Blot)
(Western blot analysis of HepG2 cells using ASGR1 Monoclonal Antibody at dilution of 1:500.)
Related Product Information for anti-ADSL antibody
Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine nucleotide cycle. The two substates of adenylosuccinate lyase (ADSL) are dephosphorylated derivatives of SAICA ribotide (SAICAR) and adenylosuccinate (S-AMP), which catalyzes an important reaction in the de novo pathway of purine biosynthesis. ADSL catalyzes two distinct reactions in the synthesis of purine nucleotides, both of which involve the _-elimination of fumarate to produce either aminoimidazole carboxamide ribotide from SAICAR or AMP from S-AMP. The Adenylosuccinate lyase deficiency is a rare autosomal recessive metabolic disorder characterized by the present of SAICA riboside and succinyladenosine (S-Ado). ADSL defect in different patients is often caused by different mutations to the enzyme.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW 55kDa
Observed MW 55kDa
Observed MW 55kDa
NCBI Official Full Name
adenylosuccinate lyase isoform c
NCBI Official Synonym Full Names
adenylosuccinate lyase
NCBI Official Symbol
ADSL
NCBI Official Synonym Symbols
ASL; AMPS; ASASE
NCBI Protein Information
adenylosuccinate lyase
UniProt Protein Name
Adenylosuccinate lyase
UniProt Gene Name
ADSL
UniProt Synonym Gene Names
AMPS; ASase
UniProt Entry Name
PUR8_HUMAN
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Product Notes
The ADSL adsl (Catalog #AAA173479) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human ADSL Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ADSL can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ADSL adsl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADSL, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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