SDS-PAGE
Fibrinogen beta chain (FGB) Recombinant Protein | FGB recombinant protein
Recombinant Human Fibrinogen beta chain (FGB)
Gene Names
FGB; HEL-S-78p
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Fibrinogen beta chain (FGB); N/A; Recombinant Human Fibrinogen beta chain (FGB); Fibrinogen beta chainCleaved into the following 2 chains:; 1. Fibrinopeptide B; 2. Fibrinogen beta chain; FGB recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
45-491aa; partial
Sequence
GHRPLDKKREEAPSLRPAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQERPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFPQQ
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
SDS-PAGE
SDS-PAGE
Related Product Information for FGB recombinant protein
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Product Categories/Family for FGB recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54.8 kDa
NCBI Official Full Name
fibrinogen beta chain isoform 2 preproprotein
NCBI Official Synonym Full Names
fibrinogen beta chain
NCBI Official Symbol
FGB
NCBI Official Synonym Symbols
HEL-S-78p
NCBI Protein Information
fibrinogen beta chain; fibrinogen, B beta polypeptide; epididymis secretory sperm binding protein Li 78p
UniProt Protein Name
Fibrinogen beta chain
UniProt Gene Name
FGB
UniProt Entry Name
FIBB_HUMAN
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Product Notes
The FGB fgb (Catalog #AAA81684) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 45-491aa; partial. The amino acid sequence is listed below: GHRPLDKKRE EAPSLRPAPP PISGGGYRAR PAKAAATQKK VERKAPDAGG CLHADPDLGV LCPTGCQLQE ALLQQERPIR NSVDELNNNV EAVSQTSSSS FQYMYLLKDL WQKRQKQVKD NENVVNEYSS ELEKHQLYID ETVNSNIPTN LRVLRSILEN LRSKIQKLES DVSAQMEYCR TPCTVSCNIP VVSGKECEEI IRKGGETSEM YLIQPDSSVK PYRVYCDMNT ENGGWTVIQN RQDGSVDFGR KWDPYKQGFG NVATNTDGKN YCGLPGEYWL GNDKISQLTR MGPTELLIEM EDWKGDKVKA HYGGFTVQNE ANKYQISVNK YRGTAGNALM DGASQLMGEN RTMTIHNGMF FSTYDRDNDG WLTSDPRKQC SKEDGGGWWY NRCHAANPNG RYYWGGQYTW DMAKHGTDDG VVWMNWKGSW YSMRKMSMKI RPFFPQQ. It is sometimes possible for the material contained within the vial of "Fibrinogen beta chain (FGB), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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