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▼Recombinant Proteins
Recombinant proteins are purified laboratory reagents created through genetic engineering for advanced biomedical research, such as immunology, neuroscience, cancer research, and more.
At AAA Biotech, also known as AAA Bio or AAABio, we provide high-quality recombinant proteins. Our various protein products are carefully tested for consistent and reliable performance. With our proteins, we offer stringent quality control, lot-to-lot consistency, and precise specificity to help you achieve accurate results in your research.
Whether you're conducting research on cell expansion, polarization, differentiation, or cell processing, we can offer the exact recombinant proteins you need in order to support your work.
Viewing 2350-2400 of 14163 product results
SDS-PAGE
Mixed lineage kinase domain-like protein (Mlkl), Recombinant Protein (Cat# AAA117120)
SDS-PAGE
Matrix protein VP40 (VP40), Recombinant Protein (Cat# AAA117121)
U1 small nuclear ribonucleoprotein A (U1A), Recombinant Protein (Cat# AAA117122)
SDS-PAGE
Legumain (LGMN), Recombinant Protein (Cat# AAA117123)
SDS-PAGE
Gelatinase (gelE), Recombinant Protein (Cat# AAA117126)
Immediate-early protein 2 (U90/U86), Recombinant Protein (Cat# AAA117127)
Sialidase-2 (NEU2), Recombinant Protein (Cat# AAA117132)
Pro-resilin (resilin), Recombinant Protein (Cat# AAA117133)
Matrix protein 1 (M), Recombinant Protein (Cat# AAA117136)
OTU domain-containing protein 5 (OTUD5), Recombinant Protein (Cat# AAA117138)
Pertussis toxin subunit 1 homolog (ptxA), Recombinant Protein (Cat# AAA117155)
Dystroglycan (DAG1), Recombinant Protein (Cat# AAA117161)
Protein bicaudal D homolog 2 (BICD2), Recombinant Protein (Cat# AAA117163)
Sorbitol dehydrogenase (Sord), Recombinant Protein (Cat# AAA117179)
Immediate-early protein 1 (U90/U89), Recombinant Protein (Cat# AAA117180)
Protein kinase C-binding protein NELL1 (Nell1), Recombinant Protein (Cat# AAA116882)
Cystatin-12 (Cst12), Recombinant Protein (Cat# AAA116885)
SDS-PAGE
Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2, Recombinant Protein (Cat# AAA116887)
Thymidylate kinase (tmk), Recombinant Protein (Cat# AAA116893)
Killer cell lectin-like receptor 3 (Klra3), Recombinant Protein (Cat# AAA116901)
Interferon regulatory factor 9 (Irf9), Recombinant Protein (Cat# AAA116903)
SDS-PAGE
Vacuolar protein sorting-associated protein 35 (VPS35), Recombinant Protein (Cat# AAA116907)
Striatin-3 (STRN3), Recombinant Protein (Cat# AAA116913)
Gastric intrinsic factor (GIF), Recombinant Protein (Cat# AAA116916)
Galactose-1-phosphate uridylyltransferase 1 (galT1), Recombinant Protein (Cat# AAA116922)
Transmembrane protease serine 2 (Tmprss2), Recombinant Protein (Cat# AAA116924)
Nucleoprotein (N), Recombinant Protein (Cat# AAA116932)
Adipocyte plasma membrane-associated protein (APMAP), Recombinant Protein (Cat# AAA116945)
SDS-PAGE
Hyaluronidase-2 (HYAL2), Recombinant Protein (Cat# AAA116947)
SDS-PAGE
Scavenger receptor cysteine-rich type 1 protein M130, Recombinant Protein (Cat# AAA116950)
Protein FAM105B (FAM105B), Recombinant Protein (Cat# AAA117446)
ATP synthase subunit epsilon, mitochondrial, Recombinant Protein (Cat# AAA117449)
Paramyosin, partial, Recombinant Protein (Cat# AAA117455)
SDS-PAGE
Phenylalanine--tRNA ligase alpha subunit, Recombinant Protein (Cat# AAA117456)
SDS-PAGE
Cytochrome P450 3A13, Recombinant Protein (Cat# AAA117457)
XIAP-associated factor 1 (XAF1), Recombinant Protein (Cat# AAA117461)
Sequence
(The Pongo pygmaeus Glutathione peroxidase 2 (GPX2) Uniprot (Q4AEI0) sequence contains one 'U' (red arrowhead). The 'U' selenocysteine is encoded by UGA and is typically used as a stop codon in prokaryotic cells, leading to early termination of translation. The lab mutates the this selenocysteine to 'S' serine for protein manufacture. In terms of the formation of selenocysteine, selenocysteine is a derivative of serine. Selenocysteine, cysteine and serine are highly similar. Selenocysteine can be regarded as either the 'S' atom of cysteine replaced by Se (selenium atom), or the 'O' atom of serine replaced by Se (selenium atom), and 'U' can be mutated to serine or cysteine. Generally, the lab mutates 'U' to serine for protein expression because mutating the ‘U’ to cysteine can cause the formation of additional disulfide bonds and may negatively affect protein expression and structure.)
Glutathione peroxidase 2 (GPX2), Recombinant Protein (Cat# AAA117480)
SDS-PAGE
Membrane-bound transcription factor site-1 protease (MBTPS1), partial, Recombinant Protein (Cat# AAA117485)
SDS-PAGE
Uromodulin (Umod), Recombinant Protein (Cat# AAA117486)
Serpin A9 (SERPINA9), Recombinant Protein (Cat# AAA117506)
SDS-PAGE
Procollagen C-endopeptidase enhancer 2 (PCOLCE2), Recombinant Protein (Cat# AAA117512)
Protein PML (Pml), Recombinant Protein (Cat# AAA117514)
SDS-PAGE
(Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 5(ADAMTS5)His-taggedYeast derived)
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5), Recombinant Protein (Cat# AAA117518)
SDS-PAGE
Endo-beta-1,6-galactanase (6GAL), Recombinant Protein (Cat# AAA117520)
Paired mesoderm homeobox protein 2 (PRRX2), Recombinant Protein (Cat# AAA116814)
ADAM DEC1 (Adamdec1), Recombinant Protein (Cat# AAA116817)
Major outer membrane porin, serovar D (ompA), Recombinant Protein (Cat# AAA116818)
Uricase (UOX), Recombinant Protein (Cat# AAA116820)
RNA binding protein fox-1 homolog 3 (Rbfox3), Recombinant Protein (Cat# AAA116832)
Protocadherin-19 (PCDH19), Recombinant Protein (Cat# AAA116853)
What Are Recombinant Proteins?
A recombinant protein is created by inserting the gene of interest into a host system like E. coli, mammalian cells, or insect cells. This protein expression method results in the large-scale production of protein in a controlled environment with highly precise structures and functionality. Proteins produced via the “Recombinant” methodology have proven themselves crucial in various biological research areas, including immunology, neuroscience, cancer research, drug delivery and development, and more.
Core Recombinant Protein Product Lines:
- Human: Produced from human genes (e.g., growth factors, cytokines).
- Animal: Derived from mouse, rat, or other animals (e.g., mouse antibodies, enzymes).
- Bacterial: Produced in bacteria like E. coli (e.g., enzymes, bacterial toxins).
- Yeast: Produced in yeast cells (e.g., surface proteins, metabolic enzymes).
- Insect:Expressed in insect cells (e.g., viral proteins, glycoproteins).
- Viral: Derived from viral genomes (e.g., spike proteins for vaccine development).
How Does It Work?
- Gene Identification and Cloning: Scientists first find the exact gene that codes for the protein they are interested in producing, and then create a copy of said gene.
- Recombinant DNA Creation: The copied gene is then inserted into a vector (a vehicle-like plasmid) that can be transported safely into your intended expression host cell/system.
- Host Cell Transformation: The vector (with the foreign gene inside) is shuttled into a host cell. This host can be a bacterium (like E. coli), yeast, insect cells, or mammalian cells, depending on the type of protein or protein characteristics needed.
- Protein Expression:The host cell “reads” the copied gene that was shuttled into it, and begins to produce the gene’s coded-for protein using its own cellular machinery. The host can continue to multiply, and with each new cell, more protein is produced.
- Protein Purification:After enough protein has been made, scientists collect the host cell and separate out the target protein. The protein is then carefully purified so it is free of contaminants, ideally active, and also safe for use.
The result is a purified recombinant protein — a lab-made protein that is biologically identical (in most respects) to the natural/native version.
We take this process a step further, offering recombinant proteins that are produced with precise control over sequence modifications, expression levels, and large-scale production. This ensures high-quality, consistent results that will be able to support your research needs and empower your scientific discoveries.
Some of the expression hosts/systems used in recombinant protein generation by AAA Biotech include:
- Escherichia coli (E. coli)
- Human (Homo sapiens)
- Chinese Hamster
- Yeast
- Insect cells (e.g., Baculovirus expression system)
Advantages Of Our Recombinant Proteins:
Recombinant Protein Offerings
| S.No | Protein Expression Systems | Quality and Bioactivity | Formats and Flexibility |
|---|---|---|---|
| 01. | E. coli, HEK293, CHO, yeast, and insect cells | Validated high bioactivity and binding activity | Ready-to-use formats (lyophilized or liquid formulations available) |
| 02. | 675+ recombinant protein products | High protein purity (≥95%) | Available in flexible pack sizes |
| 03. | Custom protein production (His-tag, GST, FLAG, and Fc fusion) | Lot-to-lot consistency through QC protocols | Wide range of targets (Cytokines, growth factors, enzymes, receptors, signaling proteins, etc.) |
Applications Of Our Recombinant Proteins
- Studying protein interactions (protein–protein or protein–DNA).
- Testing biological pathways with functional/activity assays.
- Creating standard curves in ELISA and other tests.
- Making antigens/immunogens for antibody production.
- Drug discovery and screening.
- Finding and confirming biomarkers.
- Researching cell signaling and immunity.
- Developing vaccines.
Read more about the applications of the recombinant proteins here!
Why Buy Recombinant Proteins from AAA Biotech?
1. High Purity & Verified Quality:
Most of our proteins are ≥ 95% pure. We also test the biological activity of our products where it's relevant (it will be indicated on the product page).
2. Multiple Expression Systems:
We offer proteins made in multiple host systems, and this enables researchers to pick the system that gives them the best folding, post-translational modifications, or functionality for their experiment requirements.
3. Custom & Flexible Options:
Need a special tag (His, GST, FLAG, Fc fusion)? Or a custom variant? We can provide it. Our proteins come in formats that are lab-friendly: lyophilized (dry) or “ready-to-use” liquid.
4. Rigorous Quality Control & Documentation:
Every batch is backed by strong QC. This means you can rely on product consistency — two different batches will perform similarly.
5. Wide Variety & Global Availability:
We carry a large and growing catalog of recombinant proteins to cover almost all needs in research (immunology, oncology, vaccine work, etc.)
6. Researcher-Focused Support:
Technical support, clear documentation, and user-friendly product pages help you select the right protein for your work. Plus, our user-friendly packaging and handling, and global shipping are all designed to reduce delays, damage, and hassles.
Order Recombinant Proteins Today!
We are committed to supporting the research community with recombinant proteins that display exceptional performance and reliability. Our proteins are produced using industry-standard methods and are validated to meet the needs of academic, pharmaceutical, and biotechnology laboratories.
We have a track record of delivering proteins that work — large numbers of researchers rely on them in many published studies. Browse our catalog to find the perfect protein for your research applications now!
FAQ
1. What is involved in the purification of recombinant proteins?
The purification process of these recombinant proteins is performed to isolate the specific protein produced by the host cell from unwanted substances. The process generally includes techniques such as “affinity chromatography” to separate the protein from other proteins and impurities. AAA Biotech generally offers proteins ≥ 95% pure, depending on the protein type.
2. What are some examples of popular AAA Biotech recombinant proteins?
Some examples of recombinant proteins include:
Retinoblastoma Protein (Cat # AAA10852) – reportedly used in vaccine research and antibody development. Hepatitis B Surface Antigen (HBsAg) (Cat# AAA13446) – reportedly used in diagnostic tests and vaccine development for Hepatitis B. High-Mobility Group Box 1 (HMGB1) (Cat# AAA10851) – reportedly used in inflammation and immune response research.
3. How are AAA Biotech recombinant proteins validated?
Each batch undergoes stringent quality control checks, including SDS-PAGE analysis, endotoxin testing (for select products), and activity assaying (for select products). Certificates of Analysis are provided with every product (only upon request for some products).
4. Are your proteins suitable for therapeutic development or only research?
AAA Biotech recombinant proteins are strictly for research-use only and are not intended for diagnostic or therapeutic purposes in humans or animals.
5. What types of expression systems do you use for recombinant protein production?
The production labs use a variety of expression platforms, including bacterial (E. coli), yeast, insect (baculovirus), and mammalian (HEK293, CHO) systems. The expression system used depends on the complexity and intended function/use of the protein.