SDS-PAGE
Pregnancy Associated Plasma Protein-1 (PAPP-1A) Recombinant Protein | PAPP-1A recombinant protein
Pregnancy Associated Plasma Protein-1 (PAPP-1A)
Purity
>95% by SDS-PAGE
Synonyms
Pregnancy Associated Plasma Protein-1 (PAPP-1A); N/A; PAPP-A, Pappalysin-1; Pregnancy-Associated Plasma Protein-1; Insulin-like growth factor-dependent IGF binding protein-4, EC 3.4.24.79; IGF-dependent IGFBP-4 protease; IGFBP-4ase.; PAPP-1A recombinant protein
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid
Buffer
Buffered 50% glycerol
SDS-PAGE
SDS-PAGE
Related Product Information for PAPP-1A recombinant protein
PAPP-A is a large zinc binding protein, which acts as a metalloprotease and has been shown to cleave insulin-like growth factor binding protein-4. PAPP-A can act as a regulator of IGF bioactivity in several biological systems, including the human ovary and cardiovascular systems. Recent studies have shown that levels are elevated in patients with unstable angina or acute myocardial infarction. PAPP-A is also produced in high concentrations during pregnancy and is released into the maternal circulation. Low levels of PAPP-A have been linked with a number of foetal chromosomal abnormalities, as well as pre-eclampsia and stillbirth. Recombinant PAPP-A comprises a 191 amino acid fragment (81-271) corresponding to the PAPP-A Jelly-Roll domain fragment and is expressed in E Coli with an aminoterminal hexahistidine tag. This product is not intended for therapeutic use.
Product Categories/Family for PAPP-1A recombinant protein
References
Conover, C.A. et al., 2004 Development 131 (5) 1187-1194
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Product Notes
The PAPP-1A (Catalog #AAA58762) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Pregnancy Associated Plasma Protein-1 (PAPP-1A), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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