Rabbit anti-Human TOK-1 alpha Polyclonal Antibody | anti-TOK-1 alpha antibody

TOK-1 alpha antibody

Cat. Num. AAA301596

• Gene Names: BCCIP; TOK1; TOK-1
• Reactivity: Human
• Applications: Immunofluorescence, Western Blot
• Purity: Purified by antigen-affinity chromatography.
• Synonyms: TOK-1 alpha, Antibody; TOK-1 alpha antibody; anti-TOK-1 alpha antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified by antigen-affinity chromatography.
• Form/Format: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
• Sequence Length: 322

• Applicable Applications for anti-TOK-1 alpha antibody: IF (Immunofluorescence), WB (Western Blot)
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide contain a sequence corresponding to a region within amino acids 181 and 233 (Q9P287) of BCCIP
• Target Name: TOK-1 alpha
• Preparation and Storage: Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

IF (Immunofluorescence)

(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TOK-1 alpha antibody at 1: 200 dilution.)

Application Data

(Sample (30 ug of whole cell lysate) A: A431 B: Hela 10% SDS PAGE Primary antibody diluted at 1: 1000)

Related Product Information for anti-TOK-1 alpha antibody

This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Product Categories/Family for anti-TOK-1 alpha antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 7706581
• NCBI GeneID: 56647
• NCBI Accession #: NP_057651
• NCBI GenBank Nucleotide #: NM_016567.3
• Molecular Weight: 33,242 Da
• NCBI Official Full Name: BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha
• NCBI Official Synonym Full Names: BRCA2 and CDKN1A interacting protein
• NCBI Official Symbol: BCCIP
• NCBI Official Synonym Symbols: TOK1; TOK-1
• NCBI Protein Information: BRCA2 and CDKN1A-interacting protein
• UniProt Protein Name: BRCA2 and CDKN1A-interacting protein
• UniProt Gene Name: BCCIP
• UniProt Synonym Gene Names: TOK1
• UniProt Entry Name: BCCIP_HUMAN