WB (Western Blot)
Rabbit TM6SF1 Polyclonal Antibody | anti-TM6SF1 antibody
TM6SF1 Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Synonyms
TM6SF1, Antibody; TM6SF1 Antibody; Transmembrane 6 superfamily member 1 antibody; anti-TM6SF1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
One hundred micrograms in 175-200 ul of antibody stabilization buffer. (varies by lot)
Sequence Length
370
Applicable Applications for anti-TM6SF1 antibody
WB (Western Blot), ELISA
Immunogen
Synthetic peptide taken within amino acid region 320-370 on human TM6SF1 protein.
Preparation and Storage
Store at -20°C for long term storage
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-TM6SF1 antibody
Description: Transmembrane 6 superfamily member 1 antibody affinity purified
Overview: Transmembrane 6 superfamily member 1(TM6SF1) is a 370 amino acid multi-pass membrane protein that belongs to the TM6SF family. The TM6SF family comprises of 3 members (TM6SF1-TM6SF3) and are intricately involved in chemokine signaling transduction pathways. The TM6SF1 is a new member recently characterized whose gene is located on chromosome15q12. The Euroimage consortium sequencing project identified TM6SF1 as a novel gene whose expression was limited to spleen, testis, and peripheral blood leukocytes. TM6SF1 and TM6SF2 are paralogous pair of genes, where TM6SF1 is localized on chromosome 19q12 while TM6SF2 localized on chromosome 15q12. The TM6SF1 andTMSF2 are have an overall similarity of 68% and 52% identity at the protein level. This conservation also led to discovery of 11 more genes 19p1.3-p12 with close homology to genes in the 15q24-q26 (1). The gene that encodes TM6SF1 consists of nearly 30,000 bases and maps to human chromosome 15q25 (1). Housing approximately 106 million base pairs and encoding more than 700 genes, chromosome 15 makes up about 3% of the human genome. Mutations in this chromosome caused various disorders including Angelman and Prader-Willi, Tay Sachs disease, and Marfan syndrome. TM6SF1 contains 8 transmembrane domains. The TM6SF1 gene was cloned from the tumor clonal outgrowth which was produced by spontaneously senescent normal mammary clonal out growth infected with the MMTV virus. The TM6SF1 is expressed in several spliced forms that are produced by either use of alternate initiation codons or by alternate RNA splicing. The physiological role of this protein is not known and may be a member of the orphan receptor family member (2).
TM6SF1-selective antibodies were generated against a peptide taken from the C-terminal region of the human TM6SF1 protein. The TM6SF1-selective antibodies are affinity purified on an immobilized antigen based affinity matrix. The isolated antibodies were then stabilized in antibody stabilization buffer for long-term storage. Antigenic blocking peptides ( MBS544584 ) and western blot positive controls ( MBS543328 ) are available. Antibodies can be conjugated to secondary enzymes or fluorophores upon request at nominal costs.
Overview: Transmembrane 6 superfamily member 1(TM6SF1) is a 370 amino acid multi-pass membrane protein that belongs to the TM6SF family. The TM6SF family comprises of 3 members (TM6SF1-TM6SF3) and are intricately involved in chemokine signaling transduction pathways. The TM6SF1 is a new member recently characterized whose gene is located on chromosome15q12. The Euroimage consortium sequencing project identified TM6SF1 as a novel gene whose expression was limited to spleen, testis, and peripheral blood leukocytes. TM6SF1 and TM6SF2 are paralogous pair of genes, where TM6SF1 is localized on chromosome 19q12 while TM6SF2 localized on chromosome 15q12. The TM6SF1 andTMSF2 are have an overall similarity of 68% and 52% identity at the protein level. This conservation also led to discovery of 11 more genes 19p1.3-p12 with close homology to genes in the 15q24-q26 (1). The gene that encodes TM6SF1 consists of nearly 30,000 bases and maps to human chromosome 15q25 (1). Housing approximately 106 million base pairs and encoding more than 700 genes, chromosome 15 makes up about 3% of the human genome. Mutations in this chromosome caused various disorders including Angelman and Prader-Willi, Tay Sachs disease, and Marfan syndrome. TM6SF1 contains 8 transmembrane domains. The TM6SF1 gene was cloned from the tumor clonal outgrowth which was produced by spontaneously senescent normal mammary clonal out growth infected with the MMTV virus. The TM6SF1 is expressed in several spliced forms that are produced by either use of alternate initiation codons or by alternate RNA splicing. The physiological role of this protein is not known and may be a member of the orphan receptor family member (2).
TM6SF1-selective antibodies were generated against a peptide taken from the C-terminal region of the human TM6SF1 protein. The TM6SF1-selective antibodies are affinity purified on an immobilized antigen based affinity matrix. The isolated antibodies were then stabilized in antibody stabilization buffer for long-term storage. Antigenic blocking peptides ( MBS544584 ) and western blot positive controls ( MBS543328 ) are available. Antibodies can be conjugated to secondary enzymes or fluorophores upon request at nominal costs.
Product Categories/Family for anti-TM6SF1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Transmembrane 6 superfamily member 1
NCBI Official Synonym Full Names
transmembrane 6 superfamily member 1
NCBI Official Symbol
TM6SF1
NCBI Protein Information
transmembrane 6 superfamily member 1
UniProt Protein Name
Transmembrane 6 superfamily member 1
UniProt Gene Name
TM6SF1
UniProt Entry Name
TM6S1_HUMAN
Similar Products
Product Notes
The TM6SF1 tm6sf1 (Catalog #AAA75795) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TM6SF1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TM6SF1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TM6SF1 tm6sf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TM6SF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.