WB (Western Blot)
(WB Suggested Anti-TBX1 Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate)
Rabbit TBX1 Polyclonal Antibody | anti-TBX1 antibody
TBX1 antibody - C-terminal region
Gene Names
TBX1; DGS; TGA; VCF; CAFS; CTHM; DGCR; DORV; VCFS; TBX1C; CATCH22
Reactivity
Human;Predicted Species Reactivity:Human, Mouse, Rat, Dog, Guinea Pig, Rabbit
Applications
Western Blot, Immunohistochemistry
Purity
Protein A purified
Synonyms
TBX1, Antibody; TBX1 antibody - C-terminal region; anti-TBX1 antibody
Host
Rabbit
Reactivity
Human;Predicted Species Reactivity:Human, Mouse, Rat, Dog, Guinea Pig, Rabbit
Clonality
Polyclonal
Purity/Purification
Protein A purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration
Batch dependent within range : 100uL at 0.5 - 1 mg/mL (varies by lot)
Sequence
Synthetic peptide located within the following region: PNPELRLEAPGASEPLHHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHG
Sequence Length
495
Applicable Applications for anti-TBX1 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Homology
Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TBX1
Protein Size
495 amino acids
Protein Interactions
TERF2; TERF1
Replacement Item
This antibody may replace item sc-17874 from Santa Cruz Biotechnology.
Preparation and Storage
For short term use, store at 2°C to 8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(WB Suggested Anti-TBX1 Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate)
WB (Western Blot)
(WB Suggested Anti-TBX1 Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate)
IHC (Immunohistochemistry)
(Human kidney)
IHC (Immunohistochemistry)
(Human kidney)
Related Product Information for anti-TBX1 antibody
This is a rabbit polyclonal antibody against TBX1. It was validated on Western Blot and immunohistochemistry
Target Description: TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Target Description: TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Product Categories/Family for anti-TBX1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53kDa
NCBI Official Full Name
T-box transcription factor TBX1 isoform C
NCBI Official Synonym Full Names
T-box 1
NCBI Official Symbol
TBX1
NCBI Official Synonym Symbols
DGS; TGA; VCF; CAFS; CTHM; DGCR; DORV; VCFS; TBX1C; CATCH22
NCBI Protein Information
T-box transcription factor TBX1
UniProt Protein Name
T-box transcription factor TBX1
UniProt Gene Name
TBX1
UniProt Synonym Gene Names
T-box protein 1
UniProt Entry Name
TBX1_HUMAN
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Product Notes
The TBX1 tbx1 (Catalog #AAA197586) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TBX1 antibody - C-terminal region reacts with Human;Predicted Species Reactivity:Human, Mouse, Rat, Dog, Guinea Pig, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's TBX1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TBX1 tbx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: PNPELRLEAP GASEPLHHHP YKYPAAAYDH YLGAKSRPAP YPLPGLRGHG. It is sometimes possible for the material contained within the vial of "TBX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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