Rabbit RPSA Polyclonal Antibody | anti-RPSA antibody

RPSA Rabbit Polyclonal Antibody

Cat. Num. AAA314197

• Gene Names: RPSA; SA; LBP; LRP; p40; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Western Blot
• Purity: Affinity purification
• Synonyms: RPSA, Antibody; RPSA Rabbit Polyclonal Antibody; RPSA; 37LRP; 67LR; ICAS; LAMBR; LAMR1; LBP; LBP/p40; LRP; LRP/LR; NEM/1CHD4; SA; lamR; p40; anti-RPSA antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Applicable Applications for anti-RPSA antibody: IF (Immunofluorescence), WB (Western Blot)
• Immunogen: Recombinant fusion protein of human 67kDa Laminin Receptor (NP_002286.2).
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using 67kDa Laminin Receptor antibody.)

IF (Immunofluorescence)

(Immunofluorescence analysis of U-2 OS cells using 67kDa Laminin Receptor Rabbit pAb.)

IF (Immunofluorescence)

(Immunofluorescence analysis of L929 cells using 67kDa Laminin Receptor Rabbit pAb.)

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using 67kDa Laminin Receptor antibody.)

Related Product Information for anti-RPSA antibody

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Product Categories/Family for anti-RPSA antibody

Primary Antibody

NCBI and Uniprot Product Information

• NCBI GI #: 9845502
• NCBI GeneID: 3921
• NCBI Accession #: NP_002286
• NCBI GenBank Nucleotide #: NM_002295.5
• UniProt Accession #: P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0
• Molecular Weight: Predicted: 32 kDa; ; Observed: 38 kDa
• NCBI Official Full Name: 40S ribosomal protein SA isoform 1
• NCBI Official Synonym Full Names: ribosomal protein SA
• NCBI Official Symbol: RPSA
• NCBI Official Synonym Symbols: SA; LBP; LRP; p40; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4
• NCBI Protein Information: 40S ribosomal protein SA; 37 kDa laminin receptor; 67 kDa laminin receptor; 37/67 kDa laminin receptor; laminin-binding protein precursor p40; colon carcinoma laminin-binding protein; laminin receptor 1 (67kD, ribosomal protein SA); multidrug resistance-a
• UniProt Protein Name: 40S ribosomal protein SA
• UniProt Gene Name: RPSA
• UniProt Entry Name: RSSA_HUMAN