IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PTPN7 Antibody (S44) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Rabbit anti-Human PTPN7 Polyclonal Antibody | anti-PTPN7 antibody
PTPN7 Antibody (S44)
Gene Names
PTPN7; LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PTPN7, Antibody; PTPN7 Antibody (S44); Tyrosine-protein phosphatase non-receptor type 7; Hematopoietic protein-tyrosine phosphatase; HEPTP; Protein-tyrosine phosphatase LC-PTP; PTPN7; anti-PTPN7 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PTPN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from human PTPN7.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
22-51
Sequence Length
399
Applicable Applications for anti-PTPN7 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PTPN7 Antibody (S44) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PTPN7 Antibody (S44) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of anti-PTPN7 Antibody (S44) in Jurkat cell line lysates (35ug/lane).PTPN7 (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of anti-PTPN7 Antibody (S44) in Jurkat cell line lysates (35ug/lane).PTPN7 (arrow) was detected using the purified Pab.)
Related Product Information for anti-PTPN7 antibody
PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.
Product Categories/Family for anti-PTPN7 antibody
References
Eswaran,J., Biochem. J. 395 (3), 483-491 (2006)
Mustelin,T., J. Mol. Biol. 354 (1), 150-163 (2005)
Pettiford,S.M., Leukemia 17 (2), 366-378 (2003)
Kosaki,K., J. Clin. Endocrinol. Metab. 87 (8), 3529-3533 (2002)
Mustelin,T., J. Mol. Biol. 354 (1), 150-163 (2005)
Pettiford,S.M., Leukemia 17 (2), 366-378 (2003)
Kosaki,K., J. Clin. Endocrinol. Metab. 87 (8), 3529-3533 (2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40529
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type 7 isoform 2
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 7
NCBI Official Symbol
PTPN7
NCBI Official Synonym Symbols
LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 7
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 7
UniProt Gene Name
PTPN7
UniProt Synonym Gene Names
HEPTP
UniProt Entry Name
PTN7_HUMAN
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Product Notes
The PTPN7 ptpn7 (Catalog #AAA287448) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 22-51. The PTPN7 Antibody (S44) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTPN7 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PTPN7 ptpn7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTPN7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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