IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/50.)
Rabbit PRPS1/2/1L1 Polyclonal Antibody | anti-PRPS1/2/1L1 antibody
PRPS1/2/1L1 Antibody
Gene Names
PRPS1; ARTS; DFN2; PRSI; CMTX5; DFNX1; PRS-I; PPRibP
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification.
Synonyms
PRPS1/2/1L1, Antibody; PRPS1/2/1L1 Antibody; ARTS; DFN2; PRSI; CMTX5; DFNX1; PRS-I; PPRibP/PRSII/PRPS1; PRPS3; PRPSL; PRS-III; anti-PRPS1/2/1L1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total PRPS1/2/1L1 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
3 mg/ml (varies by lot)
Sequence Length
114
Applicable Applications for anti-PRPS1/2/1L1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to residues near the N terminal of human phosphoribosyl pyrophosphate synthetase 1/2/1-like 1
Target Name
PRPS1-2-1L1
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/50.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/50.)
Application Data
(Gel: 8%SDS-PAGE Lysate: 40ug 293T cell Primary antibody: 1/750 dilution Secondary antibody dilution: 1/8000 Exposure time: 2 minutes)
Application Data
(Gel: 8%SDS-PAGE Lysate: 40ug 293T cell Primary antibody: 1/750 dilution Secondary antibody dilution: 1/8000 Exposure time: 2 minutes)
Related Product Information for anti-PRPS1/2/1L1 antibody
PRPS (phosphoribosyl pyrophosphate synthetase) proteins catalyze the synthesis of phosphoribosyl pyrophosphate (PRPP). Three human PRPS isoforms exist and are encoded by three different genes. PRPS1 and PRPS2 (also known as PRS1 and PRS2, respectively) are ubiquitously expressed, while PRPS3 (also known as PRPS1L1) is specific to the testis. PRPP is an important substrate synthesized from MgATP and ribose-5-phosphate in a reaction that requires inorganic phosphate and magnesium as a cofactor. PRPP is essential in the synthesis of nearly all nucleotides, implying that PRPS1/2 play an important role in nucleotide biosynthesis and purine metabolism. A mutation in the gene encoding PRPS1 may result in PRPS superactivity, a disease characterized by gout and the overproduction of purine nucleotides, uric acid and PRPP. PRPS1 mutations can also lead to a reduction in PRPS1 activity resulting in ARTS syndrome or CMTX5 (Charcot-Marie-Tooth disease X-linked recessive type 5).
Product Categories/Family for anti-PRPS1/2/1L1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,526 Da
NCBI Official Full Name
ribose-phosphate pyrophosphokinase 1 isoform 2
NCBI Official Synonym Full Names
phosphoribosyl pyrophosphate synthetase 1
NCBI Official Symbol
PRPS1
NCBI Official Synonym Symbols
ARTS; DFN2; PRSI; CMTX5; DFNX1; PRS-I; PPRibP
NCBI Protein Information
ribose-phosphate pyrophosphokinase 1
UniProt Protein Name
Ribose-phosphate pyrophosphokinase 1
UniProt Gene Name
PRPS1
UniProt Synonym Gene Names
PRS-I
UniProt Entry Name
PRPS1_HUMAN
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Product Notes
The PRPS1/2/1L1 prps1 (Catalog #AAA302236) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRPS1/2/1L1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PRPS1/2/1L1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PRPS1/2/1L1 prps1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRPS1/2/1L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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