Rabbit POU3F2 Polyclonal Antibody | anti-POU3F2 antibody

POU3F2 Antibody

Cat. Num. AAA40542

• Gene Names: POU3F2; BRN2; OCT7; OTF7; OTF-7; POUF3; brn-2; oct-7; N-Oct3
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Western Blot, ELISA
• Purity: POU3F2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: POU3F2, Antibody; POU3F2 Antibody; POU3F2; BRN2; OCT7; OTF7; OTF-7; POUF3; brn-2; oct-7; N-Oct3; POU domain; class 3; transcription factor 2; Nervous system-specific octamer-binding transcription factor N-Oct-3; Brain-2; POU class 3 homeobox 2; anti-POU3F2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least two isoforms are known to exist. This antibody will recognize both isoforms. POU3F2 antibody is predicted to not cross-react with other members of the POU domain class 3 family.
• Purity/Purification: POU3F2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 443

• Applicable Applications for anti-POU3F2 antibody: IF (Immunofluorescence), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Rabbit polyclonal POU3F2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human POU3F2.
• Buffer: POU3F2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: POU3F2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of POU3F2 in human brain tissue with POU3F2 antibody at 20 μg/mL.)

WB (Western Blot)

(Western blot analysis of POU3F2 in 3T3 cell lysate with POU3F2 antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-POU3F2 antibody

POU3F2 Antibody: POU3F2, also commonly known as brain-2, is a member of a family of POU domain genes expressed in mouse brain and is thought to be involved in the development of the neocortex and establishment of neural cell lineage. Recent studies suggest that POU3F2 may be involved with the development of neurodegenerative diseases as well as tumor development and proliferation. Along with the neural-lineage-specific transcription factors ASCL1 and MYT1L, POU3F2 can convert fibroblasts to functional neurons in vitro, a form of artificial stem cells termed induced neuronal (iN) cells, suggesting that these cells may be useful in the treatment of neurodegenerative diseases.

NCBI and Uniprot Product Information

• NCBI GI #: 51702521
• NCBI GeneID: 5454
• NCBI Accession #: NP_005595
• NCBI GenBank Nucleotide #: NM_005604.3
• UniProt Accession #: P20265; Q14960; Q86V54; Q9UJL0
• Molecular Weight: 49 kDa
• NCBI Official Full Name: POU domain, class 3, transcription factor 2
• NCBI Official Synonym Full Names: POU class 3 homeobox 2
• NCBI Official Symbol: POU3F2
• NCBI Official Synonym Symbols: BRN2; OCT7; OTF7; OTF-7; POUF3; brn-2; oct-7; N-Oct3
• NCBI Protein Information: POU domain, class 3, transcription factor 2; brain-2; octamer-binding protein 7; octamer-binding transcription factor 7; brain-specific homeobox/POU domain protein 2; nervous system-specific octamer-binding transcription factor N-Oct-3
• UniProt Protein Name: POU domain, class 3, transcription factor 2
• UniProt Gene Name: POU3F2
• UniProt Synonym Gene Names: BRN2; OCT7; OTF7; Brain-2; Brn-2; Oct-7; OTF-7
• UniProt Entry Name: PO3F2_HUMAN