IHC (Immunohiostchemistry)
(PKP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PKP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human PKP2 Polyclonal Antibody | anti-PKP2 antibody
PKP2 Antibody (C-term)
Gene Names
PKP2; ARVD9
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PKP2, Antibody; PKP2 Antibody (C-term); Plakophilin-2; PKP2; anti-PKP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PKP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 838-866 amino acids from the C-terminal region of human PKP2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.44 (varies by lot)
Sequence Positions
838-866
Sequence Length
837
Applicable Applications for anti-PKP2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(PKP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PKP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(PKP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PKP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(PKP2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PKP2 antibody detected the PKP2 protein (arrow).)
WB (Western Blot)
(PKP2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PKP2 antibody detected the PKP2 protein (arrow).)
Related Product Information for anti-PKP2 antibody
This gene encodes a member of the arm-repeat (armadillo)
and plakophilin gene families. Plakophilin proteins contain
numerous armadillo repeats, localize to cell desmosomes and nuclei,
and participate in linking cadherins to intermediate filaments in
the cytoskeleton. This gene product may regulate the signaling
activity of beta-catenin. Two alternately spliced transcripts
encoding two protein isoforms have been identified. A processed
pseudogene with high similarity to this locus has been mapped to
chromosome 12p13.
and plakophilin gene families. Plakophilin proteins contain
numerous armadillo repeats, localize to cell desmosomes and nuclei,
and participate in linking cadherins to intermediate filaments in
the cytoskeleton. This gene product may regulate the signaling
activity of beta-catenin. Two alternately spliced transcripts
encoding two protein isoforms have been identified. A processed
pseudogene with high similarity to this locus has been mapped to
chromosome 12p13.
Product Categories/Family for anti-PKP2 antibody
References
Fressart, V., et al. Europace 12(6):861-868(2010)
Cox, M.G., et al. Circ Arrhythm Electrophysiol 3(2):126-133(2010)
Christensen, A.H., et al. Cardiology 115(2):148-154(2010)
den Haan, A.D., et al. Circ Cardiovasc Genet 2(5):428-435(2009)
Bhuiyan, Z.A., et al. Circ Cardiovasc Genet 2(5):418-427(2009)
Cox, M.G., et al. Circ Arrhythm Electrophysiol 3(2):126-133(2010)
Christensen, A.H., et al. Cardiology 115(2):148-154(2010)
den Haan, A.D., et al. Circ Cardiovasc Genet 2(5):428-435(2009)
Bhuiyan, Z.A., et al. Circ Cardiovasc Genet 2(5):418-427(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
97415
NCBI Official Full Name
plakophilin-2 isoform 2a
NCBI Official Synonym Full Names
plakophilin 2
NCBI Official Symbol
PKP2
NCBI Official Synonym Symbols
ARVD9
NCBI Protein Information
plakophilin-2
UniProt Protein Name
Plakophilin-2
UniProt Gene Name
PKP2
UniProt Entry Name
PKP2_HUMAN
Similar Products
Product Notes
The PKP2 pkp2 (Catalog #AAA287835) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 838-866. The PKP2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PKP2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PKP2 pkp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PKP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.