Rabbit anti-Human PAK6 Polyclonal Antibody | anti-PAK6 antibody

PAK6 Antibody

Cat. Num. AAA39715

• Gene Names: PAK6; PAK5
• Reactivity: Human
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: PAK6 Antibody is affinity chromatography purified via peptide column.
• Synonyms: PAK6, Antibody; PAK6 Antibody; PAK6; PAK5; PAK-5; PAK-6; p21 protein (Cdc42/Rac)-activated kinase 6; anti-PAK6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: PAK6 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 681

• Applicable Applications for anti-PAK6 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: PAK6 antibody was raised against a 13 amino acid synthetic peptide from near the center of human PAK6.
• Buffer: PAK6 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: PAK6 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of PAK6 in Raji cells with PAK6 antibody at 10 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of PAK6 in Raji cells with PAK6 antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of PAK6 in Raji lysate with PAK6 antibody at (A) 1, (B) 2, and (C) 4 μg/mL.)

Related Product Information for anti-PAK6 antibody

PAK6 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues. Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.

NCBI and Uniprot Product Information

• NCBI GI #: 9910476
• NCBI GeneID: 56924
• NCBI Accession #: NP_064553
• NCBI GenBank Nucleotide #: NM_020168.5
• UniProt Accession #: Q9NQU5; A8K2G2; B3KYB0; G5E9R2
• Molecular Weight: 69,777 Da
• NCBI Official Full Name: serine/threonine-protein kinase PAK 6 isoform 1
• NCBI Official Synonym Full Names: p21 protein (Cdc42/Rac)-activated kinase 6
• NCBI Official Symbol: PAK6
• NCBI Official Synonym Symbols: PAK5
• NCBI Protein Information: serine/threonine-protein kinase PAK 6; p21(CDKN1A)-activated kinase 6
• UniProt Protein Name: Serine/threonine-protein kinase PAK 6
• UniProt Gene Name: PAK6
• UniProt Synonym Gene Names: PAK5; PAK-6
• UniProt Entry Name: PAK6_HUMAN