IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/40.)
Rabbit anti-Human NFKBIE Polyclonal Antibody | anti-NFKBIE antibody
NFKBIE Antibody
Gene Names
NFKBIE; IKBE
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification.
Synonyms
NFKBIE, Antibody; NFKBIE Antibody; IKBE; anti-NFKBIE antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total NFKBIE protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
1.4 mg/ml (varies by lot)
Sequence Length
500
Applicable Applications for anti-NFKBIE antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to a region derived from internal residues of human Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
Target Name
NFKBIE
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/40.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/40.)
Application Data
(Gel: 10%SDS-PAGE Lysate: 40ug Raji cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Application Data
(Gel: 10%SDS-PAGE Lysate: 40ug Raji cell Primary antibody: 1/350 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Related Product Information for anti-NFKBIE antibody
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. NFKBIE protein expression is up-regulated following NF-kB activation and during myelopoiesis. NFKBIE is able to inhibit NF-kB-directed transactivation via cytoplasmic retention of REL proteins. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NF-kB transcription factor complex. The NF-kB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm.
Product Categories/Family for anti-NFKBIE antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,864 Da
NCBI Official Full Name
NF-kappa-B inhibitor epsilon
NCBI Official Synonym Full Names
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NCBI Official Symbol
NFKBIE
NCBI Official Synonym Symbols
IKBE
NCBI Protein Information
NF-kappa-B inhibitor epsilon
UniProt Protein Name
NF-kappa-B inhibitor epsilon
UniProt Gene Name
NFKBIE
UniProt Synonym Gene Names
IKBE; NF-kappa-BIE; IkB-E; IkB-epsilon; IkappaBepsilon
UniProt Entry Name
IKBE_HUMAN
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Product Notes
The NFKBIE nfkbie (Catalog #AAA306778) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NFKBIE Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NFKBIE can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the NFKBIE nfkbie for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NFKBIE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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