IHC (Immunohiostchemistry)
(Anti- Lumican Picoband antibody, AAA46242, IHC(P)IHC(P): Mouse Brain Tissue)
anti-Mouse Lumican Polyclonal Antibody | anti-Lum antibody
Anti-Lumican Antibody
Gene Names
Lum; Ldc; SLRR2D
Reactivity
Mouse
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunogen Affinity Purified
Synonyms
Lumican, Antibody; Anti-Lumican Antibody; Lumican; Keratan sulfate proteoglycan lumican; KSPG lumican; LDC; LUM; LUM_HUMAN; Lumican precursor; SLRR2D; lumican; anti-Lum antibody
Reactivity
Mouse
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
338
Applicable Applications for anti-Lum antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
E Coli-derived mouse Lumican recombinant protein (Position: I68-N338). Mouse Lumican shares 88.9% and 98.2% amino acid (aa) sequence identity with human and rat Lumican, respectively.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti- Lumican Picoband antibody, AAA46242, IHC(P)IHC(P): Mouse Brain Tissue)
IHC (Immunohiostchemistry)
(Anti- Lumican Picoband antibody, AAA46242, IHC(P)IHC(P): Mouse Brain Tissue)
WB (Western Blot)
(Anti- Lumican Picoband antibody, AAA46242, Western blottingAll lanes: Anti Lumican (AAA46242) at 0.5ug/mlLane 1: Mouse Testis Tissue Lysate at 50ugLane 2: Mouse Thymus Tissue Lysate at 50ugLane 3: NIH3T3 Whole Cell Lysate at 40ugPredicted bind size: 38KDObserved bind size: 60KD)
WB (Western Blot)
(Anti- Lumican Picoband antibody, AAA46242, Western blottingAll lanes: Anti Lumican (AAA46242) at 0.5ug/mlLane 1: Mouse Testis Tissue Lysate at 50ugLane 2: Mouse Thymus Tissue Lysate at 50ugLane 3: NIH3T3 Whole Cell Lysate at 40ugPredicted bind size: 38KDObserved bind size: 60KD)
Related Product Information for anti-Lum antibody
Description: Rabbit IgG polyclonal antibody for Lumican(LUM) detection. Tested with WB, IHC-P, ELISA in Mouse.
Background: Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. Lumican is a major keratan sulfate proteoglycan of the cornea but is ubiquitously distributed in most mesenchymal tissues throughout the body. And Lumican is involved in collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. Corneal transparency is possible due to the exact alignment of collagen fibers by lumican (and keratocan) in the intrafibrillar space.
Background: Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. Lumican is a major keratan sulfate proteoglycan of the cornea but is ubiquitously distributed in most mesenchymal tissues throughout the body. And Lumican is involved in collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. Corneal transparency is possible due to the exact alignment of collagen fibers by lumican (and keratocan) in the intrafibrillar space.
References
1. "Entrez Gene: LUM lumican". 2. Chakravarti S, Stallings RL, SundarRaj N, Cornuet PK, Hassell JR (Jun 1995). "Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22". Genomics27 (3): 481-8. 3. Chakravarti S (2002). "Functions of lumican and fibromodulin: lessons from knockout mice". Glycoconjugate Journal 19 (4-5): 287-93.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,265 Da
NCBI Official Full Name
lumican
NCBI Official Synonym Full Names
lumican
NCBI Official Symbol
Lum
NCBI Official Synonym Symbols
Ldc; SLRR2D
NCBI Protein Information
lumican
UniProt Protein Name
Lumican
UniProt Gene Name
Lum
UniProt Synonym Gene Names
Lcn; Ldc; KSPG lumican
UniProt Entry Name
LUM_MOUSE
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Product Notes
The Lum lum (Catalog #AAA46242) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Lumican Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Lumican can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Lum lum for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lumican, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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