Application Data
(Western blotting analysis of HEK293 cells transiently transfected with human Lnk probed with Goat anti Human LnkLane A: Mock transfected cells. Lane B: transfected cells)
Goat LNK Polyclonal Antibody | anti-LNK antibody
GOAT ANTI HUMAN LNK (N-TERMINAL)
Gene Names
SH2B3; LNK; IDDM20
Applications
Western Blot
Synonyms
LNK, Antibody; GOAT ANTI HUMAN LNK (N-TERMINAL); anti-LNK antibody
Host
Goat
Clonality
Polyclonal
Isotype
IgG
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 0.5mg/ml (varies by lot)
Sequence Length
575
Applicable Applications for anti-LNK antibody
WB (Western Blot)
Perservative Stabilisers
0.02% Sodium Azide
0.5% Bovine Serum Albumin
Preparation
0.5% Bovine Serum Albumin
Preparation
Buffer Solution
TRIS buffered saline
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Western blotting analysis of HEK293 cells transiently transfected with human Lnk probed with Goat anti Human LnkLane A: Mock transfected cells. Lane B: transfected cells)
Application Data
(Western blotting analysis of HEK293 cells transiently transfected with human Lnk probed with Goat anti Human LnkLane A: Mock transfected cells. Lane B: transfected cells)
Application Data
(Western blotting analysis of MOLT4 lysate probed with Goat anti Human LNK (AAA49909))
Application Data
(Western blotting analysis of MOLT4 lysate probed with Goat anti Human LNK (AAA49909))
Related Product Information for anti-LNK antibody
Goat anti Human LNK antibodyrecognizes human SH2B adapter protein 3, also known as Lymphocyte-specific adapter protein Lnk or Lymphocyte adapter protein. LNK is a 575 amino acid SH2B adapteer protein containing a single PH domain and a single SH2 domain. Goat anti Human LNK antibody binds to an epitope within the N-terminal region of LNK, which regulates cytokine receptor-mediated and growth factor pathways, and plays an essential role in B cell lymphopoiesis. LNK mRNA is preferentially expressed in lymph node and spleen lymphocytes and the expression of LNK in vascular endothelial cells (ECs), increases in response to TNFalpha. LNK acts as a negative regulator of the pro-inflammatory molecules VCAM-1 and E-selectin induced by TNFalpha, modulation of P13-kinase and MAPK ERK1/2 activity. LNK is also involved in the negative regulation of Thrombopoietin-mediated cell proliferation and endomitosis in hematopoietic cell lines.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63,225 Da
NCBI Official Full Name
SH2B adapter protein 3 isoform 2
NCBI Official Synonym Full Names
SH2B adaptor protein 3
NCBI Official Symbol
SH2B3
NCBI Official Synonym Symbols
LNK; IDDM20
NCBI Protein Information
SH2B adapter protein 3; lymphocyte-specific adapter protein Lnk; signal transduction protein Lnk
UniProt Protein Name
SH2B adapter protein 3
UniProt Gene Name
SH2B3
UniProt Synonym Gene Names
LNK
UniProt Entry Name
SH2B3_HUMAN
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Product Notes
The LNK sh2b3 (Catalog #AAA49909) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's LNK can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the LNK sh2b3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LNK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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