WB (Western Blot)
(Western blot analysis of JAG1 Antibody expression in Mouse liver tissue lysates.)
Rabbit JAG1 Polyclonal Antibody | anti-JAG1 antibody
JAG1 Antibody
Gene Names
JAG1; AGS; AHD; AWS; HJ1; AGS1; DCHE; CD339; JAGL1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
JAG1, Antibody; JAG1 Antibody; AGS; AHD; AWS; CD 339; CD339; CD339 antigen; Headturner; hJ1; Htu; Jag 1; Jag1; JAG1_HUMAN; Jagged 1; Jagged1 (Alagille syndrome); Jagged1; JAGL1; MGC104644; OTTHUMP00000030278; Protein jagged-1; Ser 1; Ser1; Serrate 1; Slalom; anti-JAG1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
JAG1 antibody detects endogenous levels of total JAG1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1218
Applicable Applications for anti-JAG1 antibody
ELISA, WB (Western Blot)
Immunogen
A synthesized peptide derived from human JAG1
Subcellular Location
Membrane.
Tissue Specificity
Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells.
Predicted Cross Reactivity
Pig, Bovine, Horse, Rabbit, Xenopus
Similarity
Pig (93%), Bovine (93%), Horse (86%), Rabbit (100%), Xenopus (85%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of JAG1 Antibody expression in Mouse liver tissue lysates.)
WB (Western Blot)
(Western blot analysis of JAG1 Antibody expression in Mouse liver tissue lysates.)
WB (Western Blot)
(Western blot analysis of JAG1 using 293 whole cell lysates)
WB (Western Blot)
(Western blot analysis of JAG1 using 293 whole cell lysates)
Related Product Information for anti-JAG1 antibody
Function: Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Subunit Structure: Interacts with NOTCH2 and NOTCH3 (By similarity). Interacts with NOTCH1 (in the presence of calcium ions) (PubMed:18660822).
Similarity: The second EGF-like domain is atypical.
Subunit Structure: Interacts with NOTCH2 and NOTCH3 (By similarity). Interacts with NOTCH1 (in the presence of calcium ions) (PubMed:18660822).
Similarity: The second EGF-like domain is atypical.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 134 kDa
Predicted: 134 kDa
Predicted: 134 kDa
NCBI Official Full Name
protein jagged-1
NCBI Official Synonym Full Names
jagged 1
NCBI Official Symbol
JAG1
NCBI Official Synonym Symbols
AGS; AHD; AWS; HJ1; AGS1; DCHE; CD339; JAGL1
NCBI Protein Information
protein jagged-1
UniProt Protein Name
Protein jagged-1
UniProt Gene Name
JAG1
UniProt Synonym Gene Names
JAGL1; Jagged1; hJ1
Similar Products
Product Notes
The JAG1 jag1 (Catalog #AAA327443) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JAG1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's JAG1 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the JAG1 jag1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JAG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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