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IHC (Immunohistochemistry)
(Anti- IP3 receptor antibody, AAA46090,IHC(P)IHC(P): Human Lung Cancer Tissue)
Rabbit Inositol 1,4,5-trisphosphate receptor type 1 Polyclonal Antibody | anti-ITPR1 antibody
Anti-IP3 receptor Antibody
Gene Names
ITPR1; ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94
Reactivity
Human, Mouse, Rat. No cross reactivity with other proteins.
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Inositol 1,4,5-trisphosphate receptor type 1, Antibody; Anti-IP3 receptor Antibody; 4 antibody; 5-trisphosphate receptor antibody; 5-trisphosphate receptor type 1 antibody; DKFZp313E1334 antibody; DKFZp313N1434 antibody; inositol 1 4 5 triphosphate receptor type 1 antibody; Inositol 1 4 5 trisphosphate Receptor Type 1 antibody; Inositol 1 antibody; Inositol 145-trisphosphate Receptor Type 1 antibody; InsP3R1 antibody; IP3 antibody; IP3 receptor antibody; IP3 receptor isoform 1 antibody; IP3R 1 antibody; IP3R antibody; IP3R1 antibody; ITPR 1 antibody; Itpr1 antibody; ITPR1_HUMAN antibody; SCA15 antibody; SCA16 antibody; SCA29 antibody; Type 1 inositol 1 4 5 trisphosphate receptor antibody; Type 1 inositol 1 antibody; Type 1 InsP3 receptor antibody; inositol 1,4,5-trisphosphate receptor, type 1; anti-ITPR1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
2710
Applicable Applications for anti-ITPR1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human IP3 receptor recombinant protein (Position: A2411-A2758). Human IP3 receptor shares 98% and 97% amino acid (aa) sequences identity with mouse and rat IP3 receptor, respectively.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemistry)
(Anti- IP3 receptor antibody, AAA46090,IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohistochemistry)
(Anti- IP3 receptor antibody, AAA46090,IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohistochemistry)
(Anti- IP3 receptor antibody, AAA46090,IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohistochemistry)
(Anti- IP3 receptor antibody, AAA46090,IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohistochemisry)
(Anti- IP3 receptor antibody, AAA46090,IHC(P)IHC(P): Mouse Brain Tissue)
IHC (Immunohistochemisry)
(Anti- IP3 receptor antibody, AAA46090,IHC(P)IHC(P): Mouse Brain Tissue)
WB (Western Blot)
(Anti- IP3 receptor antibody, AAA46090, Western blottingAll lanes: Anti IP3 receptor (AAA46090) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Liver Tissue Lysate at 50ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: HEPG2 Whole Cell Lysate at 40ugPredicted bind size: 314KDObserved bind size: 314KD)
WB (Western Blot)
(Anti- IP3 receptor antibody, AAA46090, Western blottingAll lanes: Anti IP3 receptor (AAA46090) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Liver Tissue Lysate at 50ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: HEPG2 Whole Cell Lysate at 40ugPredicted bind size: 314KDObserved bind size: 314KD)
WB (Western Blot)
(Anti- IP3 receptor antibody, AAA46090, Western blottingAll lanes: Anti IP3 receptor (AAA46090) at 0.5ug/mlWB: Recombinant Human IP3 receptor Protein 0.5ngPredicted bind size: 45KDObserved bind size: 45KD)
WB (Western Blot)
(Anti- IP3 receptor antibody, AAA46090, Western blottingAll lanes: Anti IP3 receptor (AAA46090) at 0.5ug/mlWB: Recombinant Human IP3 receptor Protein 0.5ngPredicted bind size: 45KDObserved bind size: 45KD)
Related Product Information for anti-ITPR1 antibody
Description: Rabbit IgG polyclonal antibody for Inositol 1,4,5-trisphosphate receptor type 1(ITPR1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Background: Inositol 1,4,5-trisphosphate receptor type 1, also known as IP3R or IP3R1, is a protein that in humans is encoded by the ITPR1 gene. It is mapped to 3p26.1. The product of the ITPR1 gene is predominantly enriched in cerebellar Purkinje cells but is also concentrated in neurons in the hippocampal CA1 region, caudate-putamen, and cerebral cortex. The ITPR1 gene encodes the inositol 1,4,5-triphosphate(IP3) receptor, an intracellular IP3-gated calcium channel that modulates intracellular calcium signaling. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders.
Background: Inositol 1,4,5-trisphosphate receptor type 1, also known as IP3R or IP3R1, is a protein that in humans is encoded by the ITPR1 gene. It is mapped to 3p26.1. The product of the ITPR1 gene is predominantly enriched in cerebellar Purkinje cells but is also concentrated in neurons in the hippocampal CA1 region, caudate-putamen, and cerebral cortex. The ITPR1 gene encodes the inositol 1,4,5-triphosphate(IP3) receptor, an intracellular IP3-gated calcium channel that modulates intracellular calcium signaling. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
309,338 Da
NCBI Official Full Name
inositol 1,4,5-trisphosphate receptor type 1 isoform 1
NCBI Official Synonym Full Names
inositol 1,4,5-trisphosphate receptor, type 1
NCBI Official Symbol
ITPR1
NCBI Official Synonym Symbols
ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94
NCBI Protein Information
inositol 1,4,5-trisphosphate receptor type 1; IP3R 1; IP3 receptor; type 1 InsP3 receptor; inositol 1,4,5-triphosphate receptor, type 1; protein phosphatase 1, regulatory subunit 94; type 1 inositol 1,4,5-trisphosphate receptor
UniProt Protein Name
Inositol 1,4,5-trisphosphate receptor type 1
UniProt Gene Name
ITPR1
UniProt Synonym Gene Names
INSP3R1; IP3R 1; InsP3R1; Type 1 InsP3 receptor
UniProt Entry Name
ITPR1_HUMAN
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Product Notes
The ITPR1 itpr1 (Catalog #AAA46090) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IP3 receptor Antibody reacts with Human, Mouse, Rat. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Inositol 1,4,5-trisphosphate receptor type 1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ITPR1 itpr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Inositol 1,4,5-trisphosphate receptor type 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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