Rabbit anti-Human, Mouse HDAC3 Phospho Ser424 Polyclonal Antibody | anti-HDAC3 antibody

HDAC3 Phospho Ser424 antibody (pAb)

Cat. Num. AAA60353

• Gene Names: HDAC3; HD3; RPD3; RPD3-2
• Reactivity: Human, Mouse
• Applications: Western Blot, Dot Blot
• Purity: Protein A Chromatography
• Synonyms: HDAC3 Phospho Ser424, Antibody; HDAC3 Phospho Ser424 antibody (pAb); HDAC3 Phospho Ser424 pAb; Phospho-HDAC3 (Ser424); Phospo-HDAC3; anti-HDAC3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A Chromatography
• Form/Format: Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

• Applicable Applications for anti-HDAC3 antibody: WB (Western Blot), DB (Dot Blot)
• Immunogen: This HDAC3 antibody was raised against a synthetic peptide sequence phosphorylated at serine 424.
• Preparation and Storage: Store at -20 degree C. Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.

Application Data

Application Data

Related Product Information for anti-HDAC3 antibody

HDAC3 Phospho Ser424 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Dot blot and Western blot; it has been shown to react with Human and Mouse samples.
HDAC3 (Histone Deacetylase 3) is a member of the class I mammalian histone deacetylases (HDACs) involved in regulating chromatin structure during transcription. These enzymes catalyze the removal of acetyl groups from lysine residues of histones and other cellular proteins. Lysine N-e-acetylation is a dynamic, reversible and tightly regulated protein and histone modification that plays a major role in regulation of gene expression in various cellular functions. It consists of the transfer of an acetyl moiety from an acetyl coenzyme A to the e-amino group of a lysine residue. In vivo, acetylation is controlled by the antagonistic activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs). The HDACs are grouped into four classes, on the basis of similarity to yeast counterparts: HDAC class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC6, HDAC7, 9 and 10), class III (SIRT1-7) and class IV (HDAC11). By forming multi-protein complexes with the co-repressors SMRT and N-CoR, HDAC3 regulates the transcription of a plethora of genes. A growing list of non-histone proteins extends the role of HDAC3 beyond transcriptional repression. HDAC1, HDAC2 and HDAC3 are also ubiquitously expressed and can deacetylate both H3 and H4 in free histones or nucleosome substrate.

Product Categories/Family for anti-HDAC3 antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 13128862
• NCBI GeneID: 8841
• NCBI Accession #: NP_003874.2
• NCBI GenBank Nucleotide #: NM_003883.3
• UniProt Accession #: O15379; O43268; Q9UEI5; Q9UEV0; D3DQE1
• Molecular Weight: 48,848 Da
• NCBI Official Full Name: histone deacetylase 3
• NCBI Official Synonym Full Names: histone deacetylase 3
• NCBI Official Symbol: HDAC3
• NCBI Official Synonym Symbols: HD3; RPD3; RPD3-2
• NCBI Protein Information: histone deacetylase 3; SMAP45
• UniProt Protein Name: Histone deacetylase 3
• UniProt Gene Name: HDAC3
• UniProt Synonym Gene Names: HD3
• UniProt Entry Name: HDAC3_HUMAN