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product-image-AAA302560_WB10.jpg WB (Western Blot) (Western blot analysis of extracts of various cell lines, using GPX4 at 1:1000 dilution.)

Rabbit GPX4 Polyclonal Antibody | anti-GPX4 antibody

GPX4 Antibody

Gene Names
GPX4; MCSP; GPx-4; PHGPx; snGPx; GSHPx-4; snPHGPx
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
GPX4, Antibody; GPX4 Antibody; MCSP; GPx-4; PHGPx; snGPx; GSHPx-4; anti-GPX4 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total GPX4 protein.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
227
Applicable Applications for anti-GPX4 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human GPX4.
Target Name
GPX4
Preparation and Storage
Antibody without azide - store at -20 to -80°C. Non-hazardous. No MSDS required.

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using GPX4 at 1:1000 dilution.)

product-image-AAA302560_WB10.jpg WB (Western Blot) (Western blot analysis of extracts of various cell lines, using GPX4 at 1:1000 dilution.)

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded mouse spleen using GPX4 at dilution of 1:200 (40x lens).)

product-image-AAA302560_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded mouse spleen using GPX4 at dilution of 1:200 (40x lens).)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human esophageal cancer using GPX4 at dilution of 1:200 (40x lens).)

product-image-AAA302560_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human esophageal cancer using GPX4 at dilution of 1:200 (40x lens).)

WB (Western Blot)

(Western blot analysis of extracts of mouse kidney cell lines, using GPX4 antibody.)

product-image-AAA302560_WB15.jpg WB (Western Blot) (Western blot analysis of extracts of mouse kidney cell lines, using GPX4 antibody.)
Related Product Information for anti-GPX4 antibody
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
Product Categories/Family for anti-GPX4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
SDS-PAGE MW: 22KD
NCBI Official Full Name
phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform B
NCBI Official Synonym Full Names
glutathione peroxidase 4
NCBI Official Symbol
GPX4
NCBI Official Synonym Symbols
MCSP; GPx-4; PHGPx; snGPx; GSHPx-4; snPHGPx
NCBI Protein Information
phospholipid hydroperoxide glutathione peroxidase, mitochondrial
UniProt Protein Name
Phospholipid hydroperoxide glutathione peroxidase, mitochondrial
UniProt Gene Name
GPX4
UniProt Synonym Gene Names
PHGPx; GPx-4; GSHPx-4
UniProt Entry Name
GPX4_HUMAN

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Product Notes

The GPX4 gpx4 (Catalog #AAA302560) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPX4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GPX4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GPX4 gpx4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPX4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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