WB (Western Blot)
(Anti- GFRA1 antibody, AAA46071, Western blottingAll lanes: Anti GFRA1 (AAA46071) at 0.5ug/mlWB: Human Placenta Tissue Lysate at 50ugPredicted bind size: 51KDObserved bind size: 51KD)
Rabbit GDNF family receptor alpha-1 Polyclonal Antibody | anti-GFRA1 antibody
Anti-GFRA1 Antibody
Gene Names
GFRA1; GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1
Reactivity
Human. No cross reactivity with other proteins.
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
GDNF family receptor alpha-1, Antibody; Anti-GFRA1 Antibody; GDNF Family Receptor Alpha 1 antibody; GDNF R antibody; GDNF RA antibody; GDNF receptor alpha antibody; GDNFR alpha 1 antibody; GDNFR alpha antibody; GDNFR antibody; GDNFRA antibody; GDNFRalpha antibody; GFR alpha 1 antibody; GFR alpha1 antibody; GFR-ALPHA-1 antibody; GFRA 1 antibody; GFRA1 antibody; GFRalpha1 antibody; Glial Cell Line DErived Neurotrophic Factor Receptor Alpha antibody; Glial cell line-derived neurotrophic factor receptor alpha antibody; GPI linked anchor protein antibody; GPI-linked anchor protein antibody; MGC23045 antibody; PI linked cell surface accessory protein antibody; RET 1L antibody; RET ligand 1 antibody; RET1L antibody; RETL 1 antibody; RETL1 antibody; TGF beta related neurotrophic factor receptor 1 antibody; TGF-beta related neurotrophic factor receptor 1 antibody; TRNR 1 antibody; TRNR1 antibody; GDNF family receptor alpha 1; anti-GFRA1 antibody
Host
Rabbit
Reactivity
Human. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
460
Applicable Applications for anti-GFRA1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human GFRA1 recombinant protein (Position: D25-Q227). Human GFRA1 shares 97% amino acid (aa) sequence identity with both mouse and rat GFRA1.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti- GFRA1 antibody, AAA46071, Western blottingAll lanes: Anti GFRA1 (AAA46071) at 0.5ug/mlWB: Human Placenta Tissue Lysate at 50ugPredicted bind size: 51KDObserved bind size: 51KD)
WB (Western Blot)
(Anti- GFRA1 antibody, AAA46071, Western blottingAll lanes: Anti GFRA1 (AAA46071) at 0.5ug/mlWB: Human Placenta Tissue Lysate at 50ugPredicted bind size: 51KDObserved bind size: 51KD)
IHC (Immunohiostchemistry)
(Anti- GFRA1 antibody, AAA46071, IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti- GFRA1 antibody, AAA46071, IHC(P)IHC(P): Human Lung Cancer Tissue)
WB (Western Blot)
(Anti- GFRA1 antibody, AAA46071, Western blottingAll lanes: Anti GFRA1 (AAA46071) at 0.5ug/mlWB: Recombinant Human GFRA1 Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD)
WB (Western Blot)
(Anti- GFRA1 antibody, AAA46071, Western blottingAll lanes: Anti GFRA1 (AAA46071) at 0.5ug/mlWB: Recombinant Human GFRA1 Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD)
Related Product Information for anti-GFRA1 antibody
Description: Rabbit IgG polyclonal antibody for GDNF family receptor alpha-1(GFRA1) detection. Tested with WB, IHC-P in Human.
Background: GDNF family receptor alpha-1 (GFRalpha1), also known as the GDNF receptor or GFRA1, is a protein that in humans is encoded by the GFRA1 gene. It is mapped to chromosome 10q25.3. The protein encoded by this gene is a member of the GDNF receptor family. GFRA1 is released by neuronal cells, Schwann cells, and injured sciatic nerve. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is also a candidate gene for Hirschsprung disease. Soluble GFRA1 mediates robust recruitment of RET to lipid rafts via a mechanism requiring the RET tyrosine kinase.
Background: GDNF family receptor alpha-1 (GFRalpha1), also known as the GDNF receptor or GFRA1, is a protein that in humans is encoded by the GFRA1 gene. It is mapped to chromosome 10q25.3. The protein encoded by this gene is a member of the GDNF receptor family. GFRA1 is released by neuronal cells, Schwann cells, and injured sciatic nerve. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is also a candidate gene for Hirschsprung disease. Soluble GFRA1 mediates robust recruitment of RET to lipid rafts via a mechanism requiring the RET tyrosine kinase.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,838 Da
NCBI Official Full Name
GDNF family receptor alpha-1 isoform b preproprotein
NCBI Official Synonym Full Names
GDNF family receptor alpha 1
NCBI Official Symbol
GFRA1
NCBI Official Synonym Symbols
GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1
NCBI Protein Information
GDNF family receptor alpha-1; RET ligand 1; GDNFR-alpha-1; GDNF receptor alpha-1; GPI-linked anchor protein; PI-linked cell-surface accessory protein; TGF-beta related neurotrophic factor receptor 1; TGF-beta-related neurotrophic factor receptor 1; Glial cell line-derived neurotrophic factor receptor alpha
UniProt Protein Name
GDNF family receptor alpha-1
UniProt Gene Name
GFRA1
UniProt Synonym Gene Names
GDNFRA; RETL1; TRNR1; GDNF receptor alpha-1; GDNFR-alpha-1; GFR-alpha-1
UniProt Entry Name
GFRA1_HUMAN
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Product Notes
The GFRA1 gfra1 (Catalog #AAA46071) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GFRA1 Antibody reacts with Human. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's GDNF family receptor alpha-1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GFRA1 gfra1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GDNF family receptor alpha-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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