WB (Western Blot)
(Anti- Furin Picoband antibody, AAA46084, Western blottingAll lanes: Anti Furin (AAA46084) at 0.5ug/mlLane 1: Hela Whole Cell Lysate at 40ugLane 2: MCF-7 Whole Cell Lysate at 40ugLane 3: Colo320 Whole Cell Lysate at 40ugLane 4: SW620 Whole Cell Lysate at 40ugPredicted bind size: 87KDObserved bind size: 87KD)
Rabbit Furin Polyclonal Antibody | anti-FURIN antibody
Anti-Furin Antibody
Gene Names
FURIN; FUR; PACE; SPC1; PCSK3
Reactivity
Human. No cross reactivity with other proteins.
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
Furin, Antibody; Anti-Furin Antibody; Dibasic processing enzyme antibody; Dibasic-processing enzyme antibody; FES upstream region antibody; FUR antibody; FURIN antibody; Furin membrane associated receptor protein antibody; FURIN_HUMAN antibody; PACE antibody; Paired basic amino acid residue cleaving enzyme antibody; Paired basic amino acid residue-cleaving enzyme antibody; PCSK3 antibody; Proprotein convertase subtilisin/kexin type 3 antibody; SPC1 antibody; furin (paired basic amino acid cleaving enzyme); anti-FURIN antibody
Host
Rabbit
Reactivity
Human. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
794
Applicable Applications for anti-FURIN antibody
WB (Western Blot)
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human Furin recombinant protein (Position: T591-L794). Human Furin shares 88% amino acid (aa) sequence identity with both mouse and rat Furin.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti- Furin Picoband antibody, AAA46084, Western blottingAll lanes: Anti Furin (AAA46084) at 0.5ug/mlLane 1: Hela Whole Cell Lysate at 40ugLane 2: MCF-7 Whole Cell Lysate at 40ugLane 3: Colo320 Whole Cell Lysate at 40ugLane 4: SW620 Whole Cell Lysate at 40ugPredicted bind size: 87KDObserved bind size: 87KD)
WB (Western Blot)
(Anti- Furin Picoband antibody, AAA46084, Western blottingAll lanes: Anti Furin (AAA46084) at 0.5ug/mlLane 1: Hela Whole Cell Lysate at 40ugLane 2: MCF-7 Whole Cell Lysate at 40ugLane 3: Colo320 Whole Cell Lysate at 40ugLane 4: SW620 Whole Cell Lysate at 40ugPredicted bind size: 87KDObserved bind size: 87KD)
WB (Western Blot)
(Anti- Furin Picoband antibody, AAA46084, Western blottingAll lanes: Anti Furin (AAA46084) at 0.5ug/mlWB: Recombinant Human Furin Protein 0.5ngPredicted bind size: 40KDObserved bind size: 40KD)
WB (Western Blot)
(Anti- Furin Picoband antibody, AAA46084, Western blottingAll lanes: Anti Furin (AAA46084) at 0.5ug/mlWB: Recombinant Human Furin Protein 0.5ngPredicted bind size: 40KDObserved bind size: 40KD)
Related Product Information for anti-FURIN antibody
Description: Rabbit IgG polyclonal antibody for Furin(FURIN) detection. Tested with WB in Human.
Background: Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The Furin gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance.
Background: Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The Furin gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
86,678 Da
NCBI Official Full Name
furin preproprotein
NCBI Official Synonym Full Names
furin (paired basic amino acid cleaving enzyme)
NCBI Official Symbol
FURIN
NCBI Official Synonym Symbols
FUR; PACE; SPC1; PCSK3
NCBI Protein Information
furin; FES upstream region; dibasic processing enzyme; furin, membrane associated receptor protein; proprotein convertase subtilisin/kexin type 3; paired basic amino acid residue-cleaving enzyme
UniProt Protein Name
Furin
UniProt Gene Name
FURIN
UniProt Synonym Gene Names
FUR; PACE; PCSK3; PACE
UniProt Entry Name
FURIN_HUMAN
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Product Notes
The FURIN furin (Catalog #AAA46084) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Furin Antibody reacts with Human. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Furin can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the FURIN furin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Furin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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