IF (Immunofluorescence)
(Immunofluorescence of FLT3 in human kidney tissue with FLT3 antibody at 20 μg/mL.)
Rabbit anti-Human, Mouse FLT3 Polyclonal Antibody | anti-FLT3 antibody
FLT3 Antibody
Gene Names
FLT3; FLK2; STK1; CD135; FLK-2
Reactivity
Human, Mouse
Applications
Immunofluorescence, Western Blot, ELISA
Purity
FLT3 Antibody is affinity chromatography purified via peptide column.
Synonyms
FLT3, Antibody; FLT3 Antibody; FLT3; FLK2; STK1; CD135; FLK-2; Receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; fms-related tyrosine kinase 3; anti-FLT3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
At least three isoforms of FLT3 are known to exist; this antibody will detect all isoforms.
Purity/Purification
FLT3 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
993
Applicable Applications for anti-FLT3 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
FLT3 antibody was raised against an 18 amino acid synthetic peptide near the center of human FLT3.
Buffer
FLT3 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
FLT3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of FLT3 in human kidney tissue with FLT3 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of FLT3 in human kidney tissue with FLT3 antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of FLT3 in 3T3 cell lysate with FLT3 antibody at (A) 1 and (B)2 μg/mL.)
WB (Western Blot)
(Western blot analysis of FLT3 in 3T3 cell lysate with FLT3 antibody at (A) 1 and (B)2 μg/mL.)
Related Product Information for anti-FLT3 antibody
FLT3 Antibody: FLT3 is a member of the class III receptor tyrosine kinase family and its internal tandem duplication (ITD) is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. It is a membrane bound glycosylated protein that is expressed primarily in early hematopoietic progenitor cells. Upon binding its ligand FL, FLT3 activates multiple signaling pathways including the PI3K/Akt and Ras/MEK/MAPK pathways. In cells expressing FLT3-ITD, these pathways are constitutively on, resulting in abnormal cell growth and anti-apoptotic activity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
109 kDa
NCBI Official Full Name
receptor-type tyrosine-protein kinase FLT3
NCBI Official Synonym Full Names
fms-related tyrosine kinase 3
NCBI Official Symbol
FLT3
NCBI Official Synonym Symbols
FLK2; STK1; CD135; FLK-2
NCBI Protein Information
receptor-type tyrosine-protein kinase FLT3; CD135 antigen; FL cytokine receptor; fetal liver kinase 2; fms-like tyrosine kinase 3; stem cell tyrosine kinase 1; growth factor receptor tyrosine kinase type III
UniProt Protein Name
Receptor-type tyrosine-protein kinase FLT3
UniProt Gene Name
FLT3
UniProt Synonym Gene Names
CD135; FLK2; STK1; FLK-2; FLT-3; STK-1
UniProt Entry Name
FLT3_HUMAN
Similar Products
Product Notes
The FLT3 flt3 (Catalog #AAA40687) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FLT3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FLT3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the FLT3 flt3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FLT3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.