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product-image-AAA233118_IF13.jpg IF (Immunofluorescence) (Immunofluorescent analysis of HepG2 cells using AAA233118 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Rabbit anti-Human FBXO9 Polyclonal Antibody | anti-FBXO9 antibody

FBXO9 Antibody

Gene Names
FBXO9; FBX9; VCIA1; NY-REN-57; dJ341E18.2
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, ELISA
Purity
>95%, Protein G purified
Synonyms
FBXO9, Antibody; FBXO9 Antibody; F-box only protein 9; Cross-immune reaction antigen 1; Renal carcinoma antigen NY-REN-57; FBX9; VCIA; anti-FBXO9 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
447
Applicable Applications for anti-FBXO9 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA
Immunogen
Recombinant Human F-box only protein 9 protein (12-311AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-242808
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IF (Immunofluorescence)

(Immunofluorescent analysis of HepG2 cells using AAA233118 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

product-image-AAA233118_IF13.jpg IF (Immunofluorescence) (Immunofluorescent analysis of HepG2 cells using AAA233118 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human pancreatic tissue using AAA233118 at dilution of 1:100)

product-image-AAA233118_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded human pancreatic tissue using AAA233118 at dilution of 1:100)
Related Product Information for anti-FBXO9 antibody
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,361 Da
NCBI Official Full Name
F-box only protein 9 isoform 1
NCBI Official Synonym Full Names
F-box protein 9
NCBI Official Symbol
FBXO9
NCBI Official Synonym Symbols
FBX9; VCIA1; NY-REN-57; dJ341E18.2
NCBI Protein Information
F-box only protein 9
UniProt Protein Name
F-box only protein 9
UniProt Gene Name
FBXO9
UniProt Synonym Gene Names
FBX9; VCIA1
UniProt Entry Name
FBX9_HUMAN

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Product Notes

The FBXO9 fbxo9 (Catalog #AAA233118) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FBXO9 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FBXO9 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the FBXO9 fbxo9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBXO9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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