IHC (Immunohiostchemistry)
(EIF2AK3 Antibody (N-term) (AAA289728)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2AK3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human EIF2AK3 Polyclonal Antibody | anti-EIF2AK3 antibody
EIF2AK3 Antibody (N-term)
Gene Names
EIF2AK3; PEK; WRS; PERK
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
EIF2AK3, Antibody; EIF2AK3 Antibody (N-term); Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK; EIF2AK3; PEK; PERK; anti-EIF2AK3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This EIF2AK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-102 amino acids from the N-terminal region of human EIF2AK3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
73-102
Sequence Length
1,116
Applicable Applications for anti-EIF2AK3 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(EIF2AK3 Antibody (N-term) (AAA289728)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2AK3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(EIF2AK3 Antibody (N-term) (AAA289728)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2AK3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(EIF2AK3 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the EIF2AK3 antibody detected the EIF2AK3 protein (arrow).)
WB (Western Blot)
(EIF2AK3 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the EIF2AK3 antibody detected the EIF2AK3 protein (arrow).)
Related Product Information for anti-EIF2AK3 antibody
The protein encoded by this gene phosphorylates the alpha
subunit of eukaryotic translation-initiation factor 2 (EIF2),
leading to its inactivation, and thus to a rapid reduction of
translational initiation and repression of global protein
synthesis. It is a type I membrane protein located in the
endoplasmic reticulum (ER), where it is induced by ER stress caused
by malfolded proteins. Mutations in this gene are associated with
Wolcott-Rallison syndrome.
subunit of eukaryotic translation-initiation factor 2 (EIF2),
leading to its inactivation, and thus to a rapid reduction of
translational initiation and repression of global protein
synthesis. It is a type I membrane protein located in the
endoplasmic reticulum (ER), where it is induced by ER stress caused
by malfolded proteins. Mutations in this gene are associated with
Wolcott-Rallison syndrome.
Product Categories/Family for anti-EIF2AK3 antibody
References
Xu, H., et al. Toxicology 277 (1-3), 1-5 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kim, K.W., et al. Oncogene 29(22):3241-3251(2010)
Lee do, Y., et al. PLoS ONE 5 (5), E10489 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kim, K.W., et al. Oncogene 29(22):3241-3251(2010)
Lee do, Y., et al. PLoS ONE 5 (5), E10489 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
125216
NCBI Official Full Name
eukaryotic translation initiation factor 2-alpha kinase 3
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 2-alpha kinase 3
NCBI Official Symbol
EIF2AK3
NCBI Official Synonym Symbols
PEK; WRS; PERK
NCBI Protein Information
eukaryotic translation initiation factor 2-alpha kinase 3
UniProt Protein Name
Eukaryotic translation initiation factor 2-alpha kinase 3
UniProt Gene Name
EIF2AK3
UniProt Synonym Gene Names
PEK; PERK; HsPEK
UniProt Entry Name
E2AK3_HUMAN
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Product Notes
The EIF2AK3 eif2ak3 (Catalog #AAA289728) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 73-102. The EIF2AK3 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EIF2AK3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the EIF2AK3 eif2ak3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EIF2AK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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