IHC (Immunohistochemisry)
(CSRP2 Antibody (Center) (AAA285336)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSRP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit CSRP2 Polyclonal Antibody | anti-CSRP2 antibody
CSRP2 Antibody (Center)
Gene Names
CSRP2; CRP2; LMO5; SmLIM
Reactivity
Human (Predicted Reactivity: Bovine)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CSRP2, Antibody; CSRP2 Antibody (Center); Cysteine and glycine-rich protein 2; Cysteine-rich protein 2; CRP2; LIM domain only protein 5; LMO-5; Smooth muscle cell LIM protein; SmLIM; CSRP2; LMO5; SMLIM; anti-CSRP2 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CSRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the Central region of human CSRP2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
68-96
Sequence Length
193
Applicable Applications for anti-CSRP2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Function
Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
Cellular Location
Nucleus.
Tissue Location
Highly expressed in the aorta, but not in heart and skeletal muscle EMBL.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(CSRP2 Antibody (Center) (AAA285336)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSRP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(CSRP2 Antibody (Center) (AAA285336)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSRP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of CSRP2 (arrow) using rabbit polyclonal CSRP2 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CSRP2 gene.)
WB (Western Blot)
(Western blot analysis of CSRP2 (arrow) using rabbit polyclonal CSRP2 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CSRP2 gene.)
WB (Western Blot)
(CSRP2 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CSRP2 antibody detected the CSRP2 protein (arrow).)
WB (Western Blot)
(CSRP2 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CSRP2 antibody detected the CSRP2 protein (arrow).)
Related Product Information for anti-CSRP2 antibody
CSRP2 is a member of the CSRP family of genes, encoding a
group of LIM domain proteins, which may be involved in regulatory
processes important for development and cellular differentiation.
CRP2 contains two copies of the cysteine-rich amino acid sequence
motif (LIM) with putative zinc-binding activity, and may be
involved in regulating ordered cell growth. Other genes in the
family include CSRP1 and CSRP3.
group of LIM domain proteins, which may be involved in regulatory
processes important for development and cellular differentiation.
CRP2 contains two copies of the cysteine-rich amino acid sequence
motif (LIM) with putative zinc-binding activity, and may be
involved in regulating ordered cell growth. Other genes in the
family include CSRP1 and CSRP3.
References
Stearns, M.E., et al. Mol. Cancer Res. 1(9):631-642(2003)
Wang, M., et al. Cancer Biol. Ther. 1(5):556-563(2002)
Weiskirchen, R., et al. Biochem. J. 359 (PT 3), 485-496 (2001) :
Weiskirchen, R., et al. Biochem. Biophys. Res. Commun. 274(3):655-663(2000)
Weiskirchen, R., et al. Genomics 44(1):83-93(1997)
Wang, M., et al. Cancer Biol. Ther. 1(5):556-563(2002)
Weiskirchen, R., et al. Biochem. J. 359 (PT 3), 485-496 (2001) :
Weiskirchen, R., et al. Biochem. Biophys. Res. Commun. 274(3):655-663(2000)
Weiskirchen, R., et al. Genomics 44(1):83-93(1997)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
cysteine and glycine-rich protein 2
NCBI Official Synonym Full Names
cysteine and glycine-rich protein 2
NCBI Official Symbol
CSRP2
NCBI Official Synonym Symbols
CRP2; LMO5; SmLIM
NCBI Protein Information
cysteine and glycine-rich protein 2
UniProt Protein Name
Cysteine and glycine-rich protein 2
UniProt Gene Name
CSRP2
UniProt Synonym Gene Names
LMO5; SMLIM; CRP2; LMO-5; SmLIM
UniProt Entry Name
CSRP2_HUMAN
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Product Notes
The CSRP2 csrp2 (Catalog #AAA285336) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 68-96. The CSRP2 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's CSRP2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CSRP2 csrp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CSRP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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