IHC (Immunohiostchemistry)
(Immunochemical staining of human CLCA1 in human colon with rabbit polyclonal antibody at 1:3000 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human CLCA1 Polyclonal Antibody | anti-CLCA1 antibody
Anti-CLCA1 Antibody, Rabbit Polyclonal
Gene Names
CLCA1; CACC; GOB5; CACC1; CLCRG1; CaCC-1; hCLCA1; hCaCC-1
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
CLCA1, Antibody; Anti-CLCA1 Antibody, Rabbit Polyclonal; CLCA1 Antibody, Rabbit PAb, Antigen Affinity Purified; chloride channel accessory 1; Anti-CACC Antibody; Anti-CaCC-1 Antibody; Anti-CACC1 Antibody; Anti-CLCRG1 Antibody; Anti-GOB5 Antibody; Anti-hCaCC-1 Antibody; Anti-hCLCA1 Antibody; anti-CLCA1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human CLCA1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-CLCA1 antibody
IHC (Immunohistochemistry)
Immunogen
A synthetic peptide corresponding to the center region of the Human CLCA1
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human CLCA1, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Immunochemical staining of human CLCA1 in human colon with rabbit polyclonal antibody at 1:3000 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohiostchemistry)
(Immunochemical staining of human CLCA1 in human colon with rabbit polyclonal antibody at 1:3000 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human CLCA1 in human small intestine with rabbit polyclonal antibody at 1:3000 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human CLCA1 in human small intestine with rabbit polyclonal antibody at 1:3000 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-CLCA1 antibody
The chloride channel calcium-activated (CLCA) family are secreted proteins that regulate both chloride transport and mucin expression, thus controlling the production of mucus in respiratory and other systems. Accordingly, human CLCA1 is a critical mediator of hypersecretory lung diseases, such as asthma, chronic obstructive pulmonary disease, and cystic fibrosis, that manifest mucus obstruction. The secreted goblet cell protein CLCA1 (chloride channel regulator, calcium-activated-1) is, in addition to its established role in epithelial chloride conductance regulation, thought to act as a multifunctional signaling protein, including cellular differentiation pathways and induction of mucus production. Specifically, CLCA1 has recently been shown to modulate early immune responses by regulation of cytokines. Chloride channel accessory 1 (CLCA1) belongs to the calcium-sensitive chloride conductance protein family, which is mainly expressed in the colon, small intestine and appendix.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
100,226 Da
NCBI Official Full Name
calcium-activated chloride channel regulator 1
NCBI Official Synonym Full Names
chloride channel accessory 1
NCBI Official Symbol
CLCA1
NCBI Official Synonym Symbols
CACC; GOB5; CACC1; CLCRG1; CaCC-1; hCLCA1; hCaCC-1
NCBI Protein Information
calcium-activated chloride channel regulator 1; calcium-dependent chloride channel-1; calcium-activated chloride channel protein 1; CLCA family member 1, chloride channel regulator; calcium-activated chloride channel family member 1; chloride channel, cal
UniProt Protein Name
Calcium-activated chloride channel regulator 1
UniProt Gene Name
CLCA1
UniProt Synonym Gene Names
CACC1; hCLCA1; CaCC-1; hCaCC-1
UniProt Entry Name
CLCA1_HUMAN
Similar Products
Product Notes
The CLCA1 clca1 (Catalog #AAA255153) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CLCA1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLCA1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CLCA1 clca1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLCA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.