IHC (Immunohiostchemistry)
(CHMP2B Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CHMP2B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit CHMP2B Polyclonal Antibody | anti-CHMP2B antibody
CHMP2B Antibody (N-term)
Gene Names
CHMP2B; DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CHMP2B, Antibody; CHMP2B Antibody (N-term); Charged multivesicular body protein 2b; CHMP25; Chromatin-modifying protein 2b; CHMP2b; Vacuolar protein sorting-associated protein 2-2; Vps2-2; hVps2-2; CHMP2B; anti-CHMP2B antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CHMP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHMP2B.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
1-30
Sequence Length
172
Applicable Applications for anti-CHMP2B antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CHMP2B Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CHMP2B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(CHMP2B Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CHMP2B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(CHMP2B Antibody (N-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the CHMP2B antibody detected the CHMP2B protein (arrow).)
WB (Western Blot)
(CHMP2B Antibody (N-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the CHMP2B antibody detected the CHMP2B protein (arrow).)
Related Product Information for anti-CHMP2B antibody
This gene encodes a component of the heteromeric ESCRT-III
complex (Endosomal Sorting Complex Required for Transport III) that
functions in the recycling or degradation of cell surface
receptors. ESCRT-III functions in the concentration and
invagination of ubiquitinated endosomal cargos into intralumenal
vesicles. The protein encoded by this gene is found as a monomer in
the cytosol or as an oligomer in ESCRT-III complexes on endosomal
membranes. It is expressed in neurons of all major regions of the
brain. Mutations in this gene result in one form of familial
frontotemporal lobar degeneration.
complex (Endosomal Sorting Complex Required for Transport III) that
functions in the recycling or degradation of cell surface
receptors. ESCRT-III functions in the concentration and
invagination of ubiquitinated endosomal cargos into intralumenal
vesicles. The protein encoded by this gene is found as a monomer in
the cytosol or as an oligomer in ESCRT-III complexes on endosomal
membranes. It is expressed in neurons of all major regions of the
brain. Mutations in this gene result in one form of familial
frontotemporal lobar degeneration.
Product Categories/Family for anti-CHMP2B antibody
References
Kaivorinne, A.L., et al. Eur. J. Neurol. 17(11):1393-1395(2010)
Ghanim, M., et al. J. Neurol. (2010) In press :
Yamazaki, Y., et al. Neurosci. Lett. 477(2):86-90(2010)
Tsai, C.P., et al. Neurobiol. Aging (2010) In press :
Cox, L.E., et al. PLoS ONE 5 (3), E9872 (2010) :
Ghanim, M., et al. J. Neurol. (2010) In press :
Yamazaki, Y., et al. Neurosci. Lett. 477(2):86-90(2010)
Tsai, C.P., et al. Neurobiol. Aging (2010) In press :
Cox, L.E., et al. PLoS ONE 5 (3), E9872 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23907
NCBI Official Full Name
charged multivesicular body protein 2b isoform 2
NCBI Official Synonym Full Names
charged multivesicular body protein 2B
NCBI Official Symbol
CHMP2B
NCBI Official Synonym Symbols
DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5
NCBI Protein Information
charged multivesicular body protein 2b
UniProt Protein Name
Charged multivesicular body protein 2b
UniProt Gene Name
CHMP2B
UniProt Synonym Gene Names
CHMP2b; Vps2-2; hVps2-2
UniProt Entry Name
CHM2B_HUMAN
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Product Notes
The CHMP2B chmp2b (Catalog #AAA287233) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The CHMP2B Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's CHMP2B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CHMP2B chmp2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHMP2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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