IHC (Immunohiostchemistry)
(CCT4 Antibody (N-term) (AAA288806)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCT4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit CCT4 Polyclonal Antibody | anti-CCT4 antibody
CCT4 Antibody (N-term)
Gene Names
CCT4; SRB; Cctd; CCT-DELTA
Reactivity
Human (Predicted Reactivity: Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CCT4, Antibody; CCT4 Antibody (N-term); T-complex protein 1 subunit delta; TCP-1-delta; CCT-delta; Stimulator of TAR RNA-binding; CCT4; CCTD; SRB; anti-CCT4 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CCT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human CCT4.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
4-32
Sequence Length
509
Applicable Applications for anti-CCT4 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CCT4 Antibody (N-term) (AAA288806)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCT4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(CCT4 Antibody (N-term) (AAA288806)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCT4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(CCT4 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CCT4 antibody detected the CCT4 protein (arrow).)
WB (Western Blot)
(CCT4 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CCT4 antibody detected the CCT4 protein (arrow).)
Related Product Information for anti-CCT4 antibody
The chaperonin containing TCP1 (MIM 186980) complex (CCT),
also called the TCP1 ring complex, consists of 2 back-to-back
rings, each containing 8 unique but homologous subunits, such as
CCT4. CCT assists the folding of newly translated polypeptide
substrates through multiple rounds of ATP-driven release and
rebinding of partially folded intermediate forms. Substrates of CCT
include the cytoskeletal proteins actin (see MIM 102560) and
tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330)
(Won et al., 1998 [PubMed 9819444]).
also called the TCP1 ring complex, consists of 2 back-to-back
rings, each containing 8 unique but homologous subunits, such as
CCT4. CCT assists the folding of newly translated polypeptide
substrates through multiple rounds of ATP-driven release and
rebinding of partially folded intermediate forms. Substrates of CCT
include the cytoskeletal proteins actin (see MIM 102560) and
tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330)
(Won et al., 1998 [PubMed 9819444]).
Product Categories/Family for anti-CCT4 antibody
References
Mukherjee, K., et al. BMC Evol. Biol. 10, 64 (2010) :
Zebol, J.R., et al. Int. J. Biochem. Cell Biol. 41(4):822-827(2009)
Chi, A., et al. J. Proteome Res. 5(11):3135-3144(2006)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Imai, Y., et al. J. Biol. Chem. 278(51):51901-51910(2003)
Zebol, J.R., et al. Int. J. Biochem. Cell Biol. 41(4):822-827(2009)
Chi, A., et al. J. Proteome Res. 5(11):3135-3144(2006)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Imai, Y., et al. J. Biol. Chem. 278(51):51901-51910(2003)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57924
NCBI Official Full Name
T-complex protein 1 subunit delta isoform b
NCBI Official Synonym Full Names
chaperonin containing TCP1, subunit 4 (delta)
NCBI Official Symbol
CCT4
NCBI Official Synonym Symbols
SRB; Cctd; CCT-DELTA
NCBI Protein Information
T-complex protein 1 subunit delta
UniProt Protein Name
T-complex protein 1 subunit delta
UniProt Gene Name
CCT4
UniProt Synonym Gene Names
CCTD; SRB; TCP-1-delta
UniProt Entry Name
TCPD_HUMAN
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Product Notes
The CCT4 cct4 (Catalog #AAA288806) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 4-32. The CCT4 Antibody (N-term) reacts with Human (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's CCT4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CCT4 cct4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCT4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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