IHC (Immunohistochemisry)
(Immunofluorescent analysis of A549 cells using AAA233138 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Rabbit anti-Human, Rat BACE2 Polyclonal Antibody | anti-BACE2 antibody
BACE2 Antibody
Gene Names
BACE2; ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1
Reactivity
Human, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
>95%, Protein G purified
Synonyms
BACE2, Antibody; BACE2 Antibody; Beta-secretase 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; ASP1; Asp 1; Beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; Down region aspartic protease; DRAP; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase; BACE2; AEPLC; ALP56; ASP21; CDA13; UNQ418/PRO852; anti-BACE2 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
518
Applicable Applications for anti-BACE2 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant Human Beta-secretase 2 protein (84-157AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10048 / sc-10049 / sc-10051 / sc-15388
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohistochemisry)
(Immunofluorescent analysis of A549 cells using AAA233138 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IHC (Immunohistochemisry)
(Immunofluorescent analysis of A549 cells using AAA233138 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human gastric cancer using AAA233138 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human gastric cancer using AAA233138 at dilution of 1:100)
WB (Western Blot)
(Western BlotPositive WB detected in: A549 whole cell lysate,HL-60 whole cell lysate,Hela whole cell lysate,SH-SY5Y whole cell lysate,Rat spleen tissueAll lanes: BACE2 antibody at 2.5ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 57,51,43,39,47 KDaObserved band size: 57,43 KDa)
WB (Western Blot)
(Western BlotPositive WB detected in: A549 whole cell lysate,HL-60 whole cell lysate,Hela whole cell lysate,SH-SY5Y whole cell lysate,Rat spleen tissueAll lanes: BACE2 antibody at 2.5ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 57,51,43,39,47 KDaObserved band size: 57,43 KDa)
Related Product Information for anti-BACE2 antibody
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,476 Da
NCBI Official Full Name
beta-secretase 2 isoform A preproprotein
NCBI Official Synonym Full Names
beta-site APP-cleaving enzyme 2
NCBI Official Symbol
BACE2
NCBI Official Synonym Symbols
ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1
NCBI Protein Information
beta-secretase 2
UniProt Protein Name
Beta-secretase 2
UniProt Gene Name
BACE2
UniProt Synonym Gene Names
AEPLC; ALP56; ASP21; ASP1; Asp 1; Beta-site APP cleaving enzyme 2; DRAP
UniProt Entry Name
BACE2_HUMAN
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Product Notes
The BACE2 bace2 (Catalog #AAA233138) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BACE2 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BACE2 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the BACE2 bace2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BACE2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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