IF (Immunofluorescence)
(Immunofluorescence of APC11 in 3T3 cells with APC11 antibody at 20 μg/mL.)
Rabbit APC11 Polyclonal Antibody | anti-ANAPC11 antibody
APC11 Antibody
Gene Names
ANAPC11; APC11; Apc11p; HSPC214
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, ELISA
Purity
APC11 Antibody is affinity chromatography purified via peptide column.
Synonyms
APC11, Antibody; APC11 Antibody; APC11; Apc11p; HSPC214; Anaphase-promoting complex subunit 11; Cyclosome subunit 11; anaphase promoting complex subunit 11; anti-ANAPC11 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
APC11 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
196
Applicable Applications for anti-ANAPC11 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
APC11 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC11.
Buffer
APC11 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
APC11 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of APC11 in 3T3 cells with APC11 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of APC11 in 3T3 cells with APC11 antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of APC11 in HeLa cell lysate with APC11 antibody at 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of APC11 in HeLa cell lysate with APC11 antibody at 1 μg/mL.)
Related Product Information for anti-ANAPC11 antibody
APC11 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC11, together with APC2 and Ubc4, form the minimal APC ubiquitin ligase module.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,644 Da
NCBI Official Full Name
anaphase-promoting complex subunit 11 isoform 1
NCBI Official Synonym Full Names
anaphase promoting complex subunit 11
NCBI Official Symbol
ANAPC11
NCBI Official Synonym Symbols
APC11; Apc11p; HSPC214
NCBI Protein Information
anaphase-promoting complex subunit 11; cyclosome subunit 11; APC11 anaphase promoting complex subunit 11 homolog; hepatocellular carcinoma-associated RING finger protein; anaphase promoting complex subunit 11 (yeast APC11 homolog)
UniProt Protein Name
Anaphase-promoting complex subunit 11
UniProt Gene Name
ANAPC11
UniProt Synonym Gene Names
APC11
UniProt Entry Name
APC11_HUMAN
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Product Notes
The ANAPC11 anapc11 (Catalog #AAA40414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC11 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's APC11 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ANAPC11 anapc11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APC11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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