Rabbit 20S Proteasome alpha3 Polyclonal Antibody | anti-PSMA3 antibody

20S Proteasome alpha3 (phospho Ser250) Polyclonal Antibody

Cat. Num. AAA293973

• Gene Names: PSMA3; HC8; PSC3
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Synonyms: 20S Proteasome alpha3, Antibody; 20S Proteasome alpha3 (phospho Ser250) Polyclonal Antibody; PSMA3; HC8; PSC8; Proteasome subunit alpha type-3; Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; Proteasome component C8; anti-PSMA3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal

• Applicable Applications for anti-PSMA3 antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohistochemistry)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.)

WB (Western Blot)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.)

IHC (Immunohiostchemistry)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.)

WB (Western Blot)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.)

Related Product Information for anti-PSMA3 antibody

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.

NCBI and Uniprot Product Information

• NCBI GI #: 4506183
• NCBI GeneID: 5684
• NCBI Accession #: NP_002779.1
• NCBI GenBank Nucleotide #: NM_002788.3
• UniProt Accession #: P25788; Q86U83; Q8N1D8; Q9BS70; B2RCK6
• Molecular Weight: 28,433 Da
• NCBI Official Full Name: proteasome subunit alpha type-3 isoform 1
• NCBI Official Synonym Full Names: proteasome (prosome, macropain) subunit, alpha type, 3
• NCBI Official Symbol: PSMA3
• NCBI Official Synonym Symbols: HC8; PSC3
• NCBI Protein Information: proteasome subunit alpha type-3; macropain subunit C8; proteasome subunit C8; proteasome component C8; multicatalytic endopeptidase complex subunit C8
• UniProt Protein Name: Proteasome subunit alpha type-3
• UniProt Gene Name: PSMA3
• UniProt Synonym Gene Names: HC8; PSC8
• UniProt Entry Name: PSA3_HUMAN