IHC (Immunohiostchemistry)
Mouse Sodium Iodide Symporter Monoclonal Antibody | anti-NIS antibody
Sodium Iodide Symporter Monoclonal Antibody
Gene Names
SLC5A5; NIS; TDH1
Applications
Immunoblot, Western Blot
Synonyms
Sodium Iodide Symporter, Antibody; Sodium Iodide Symporter Monoclonal Antibody; Anti-Sodium Iodine Symporter; anti-NIS antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody recognizes human, mouse and rat NIS.
Sequence Length
643
Applicable Applications for anti-NIS antibody
IB (Immunoblot)
Antigen
Synthetic peptide corresponding to aa625-643 (SWTPCVGHDGGRDQQETNL) at the C-terminus of the extramembranous domain of human NIS.
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
Application Data
Application Data
Related Product Information for anti-NIS antibody
The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells. This is an important step in the process of iodide organification and the formation of triiodothyronine and thyroxine. The importance of NIS is related to its role in thyroid function, the pathogenesis of thyroid disease, and its expression (or lack of expression) in thyroid malignancies. It has also been suggested that NIS may represent an autoantigen in autoimmune disease of the thyroid.
Product Categories/Family for anti-NIS antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
68,666 Da
NCBI Official Full Name
sodium iodide symporter
NCBI Official Synonym Full Names
solute carrier family 5 member 5
NCBI Official Symbol
SLC5A5
NCBI Official Synonym Symbols
NIS; TDH1
NCBI Protein Information
sodium/iodide cotransporter
UniProt Protein Name
Sodium/iodide cotransporter
UniProt Gene Name
SLC5A5
UniProt Synonym Gene Names
NIS; Na(+)/I(-) cotransporter; Na(+)/I(-) symporter
UniProt Entry Name
SC5A5_HUMAN
Similar Products
Product Notes
The NIS slc5a5 (Catalog #AAA47756) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Sodium Iodide Symporter can be used in a range of immunoassay formats including, but not limited to, IB (Immunoblot). Researchers should empirically determine the suitability of the NIS slc5a5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sodium Iodide Symporter, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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