ICC (Immunocytochemistry)
(Immunocytochemistry of Retinoid X Receptor alpha (green) in MCF-7 using Retinoid X Receptor alpha antibody at dilution 1/20, and DAPI(blue))
Retinoid X Receptor alpha Monoclonal Antibody | anti-RXRA antibody
Retinoid X Receptor alpha Rabbit mAb
Gene Names
RXRA; NR2B1
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot
Purity
Affinity Purified
Synonyms
Retinoid X Receptor alpha, Antibody; Retinoid X Receptor alpha Rabbit mAb; NR2B1; anti-RXRA antibody
Host
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
S04-6C3
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration
0.3mg/ml (varies by lot)
Applicable Applications for anti-RXRA antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen
A synthetic peptide of human Retinoid X Receptor alpha
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
ICC (Immunocytochemistry)
(Immunocytochemistry of Retinoid X Receptor alpha (green) in MCF-7 using Retinoid X Receptor alpha antibody at dilution 1/20, and DAPI(blue))
ICC (Immunocytochemistry)
(Immunocytochemistry of Retinoid X Receptor alpha (green) in MCF-7 using Retinoid X Receptor alpha antibody at dilution 1/20, and DAPI(blue))
WB (Western Blot)
(Western blot detection of Retinoid X Receptor alpha in Hela,C6 cell lysates using Retinoid X Receptor alpha Rabbit mAb(1:500 diluted).Predicted band size:51kDa.Observed band size:51kDa.)
WB (Western Blot)
(Western blot detection of Retinoid X Receptor alpha in Hela,C6 cell lysates using Retinoid X Receptor alpha Rabbit mAb(1:500 diluted).Predicted band size:51kDa.Observed band size:51kDa.)
Related Product Information for anti-RXRA antibody
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes.
Product Categories/Family for anti-RXRA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
50,811 Da
NCBI Official Full Name
Retinoic acid receptor RXR-alpha
NCBI Official Synonym Full Names
retinoid X receptor, alpha
NCBI Official Symbol
RXRA
NCBI Official Synonym Symbols
NR2B1
NCBI Protein Information
retinoic acid receptor RXR-alpha; retinoid X nuclear receptor alpha; nuclear receptor subfamily 2 group B member 1
UniProt Protein Name
Retinoic acid receptor RXR-alpha
UniProt Gene Name
RXRA
UniProt Synonym Gene Names
NR2B1
UniProt Entry Name
RXRA_HUMAN
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Product Notes
The RXRA rxra (Catalog #AAA314452) is an Antibody produced from Recombinant Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Retinoid X Receptor alpha Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Retinoid X Receptor alpha can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the RXRA rxra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Retinoid X Receptor alpha, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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