Mouse ICAM-1 Monoclonal Antibody | anti-ICAM-1 antibody

Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2)

Cat. Num. AAA197030

• Gene Names: ICAM1; BB2; CD54; P3.58
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunoprecipitation, Flow Cytometry, Functional Assay, Immunohistochemistry
• Purity: >95% by SDS-PAGE and HPLC; This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
• Synonyms: ICAM-1, Antibody; Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (15.2); Intercellular adhesion molecule 1; ICAM1; Major group rhinovirus receptor; CD54; anti-ICAM-1 antibody

• Host: Mouse
• Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Clone Number: 15.2
• Specificity: Mouse anti-Human Inter-Cellular Adhesion Molecule 1 (ICAM-1) (Clone 15.2) recognizes an epitope on Human ICAM-1
• Purity/Purification: >95% by SDS-PAGE and HPLC; This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
• Form/Format: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
• Concentration: 1.0-5.0mg/ml (varies by lot)

• Applicable Applications for anti-ICAM-1 antibody: WB (Western Blot), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
• Endotoxin: <1.0 EU/mg as determined by the LAL method
• Immunogen: Human infant thymocytes and Sezary cells
• Aggregation: Aggregation level <= 5%
• Antigen Distribution: The CD54 antigen is a membrane glycoprotein with a wide tissue distribution that includes vascular endothelium and many cells of the immune system. CD54 is weakly expressed on resting peripheral blood lymphocytes. Upon activation by mitogens, the CD54 antigen is strongly expressed on B-cells, T-cells, macrophages and granulocytes. CD54 is the receptor for rhinovirus es and malaria.
• Preparation and Storage: This antibody is stable for at least one week when stored sterile at 2-8 degree C. For long term storage aseptically aliquot in working volumes without diluting and store at -80 degree C. Avoid Repeated Freeze Thaw Cycles.

Application Data

Application Data

IF (Immunofluorescence)

Related Product Information for anti-ICAM-1 antibody

Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.

Product Categories/Family for anti-ICAM-1 antibody

Low Endotoxin

NCBI and Uniprot Product Information

• NCBI GI #: 167466198
• NCBI GeneID: 3383
• NCBI Accession #: NP_000192.2
• NCBI GenBank Nucleotide #: NM_000201.2
• UniProt Accession #: P05362; Q5NKV7; Q96B50; B2R6M3
• Molecular Weight: 57,825 Da
• NCBI Official Full Name: intercellular adhesion molecule 1
• NCBI Official Synonym Full Names: intercellular adhesion molecule 1
• NCBI Official Symbol: ICAM1
• NCBI Official Synonym Symbols: BB2; CD54; P3.58
• NCBI Protein Information: intercellular adhesion molecule 1; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
• UniProt Protein Name: Intercellular adhesion molecule 1
• UniProt Gene Name: ICAM1
• UniProt Synonym Gene Names: ICAM-1
• UniProt Entry Name: ICAM1_HUMAN