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product-image-AAA312268_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-GARS antibody. Counter stained with hematoxylin.)

Rabbit GARS Monoclonal Antibody | anti-GARS antibody

GARS Antibody

Gene Names
GARS; HMN5; CMT2D; DSMAV; GlyRS; SMAD1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
GARS, Antibody; GARS Antibody; AP 4 A synthetase antibody; Charcot Marie Tooth neuropathy 2D antibody; Charcot Marie Tooth neuropathy neuronal type D antibody; CMT2D antibody; Diadenosine tetraphosphate synthetase antibody; DSMAV antibody; EC 6.1.1.14 antibody; Glycine tRNA ligase antibody; Glycyl tRNA synthetase antibody; GlyRS antibody; HMN5 antibody; SMAD1 antibody; anti-GARS antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
SC0651
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-GARS antibody
IHC (Immunohistochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-GARS antibody. Counter stained with hematoxylin.)

product-image-AAA312268_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-GARS antibody. Counter stained with hematoxylin.)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-GARS antibody. Counter stained with hematoxylin.)

product-image-AAA312268_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-GARS antibody. Counter stained with hematoxylin.)

WB (Western Blot)

(Western blot analysis of GARS on Raji cells lysates using anti-GARS antibody at 1/1, 000 dilution.)

product-image-AAA312268_WB15.jpg WB (Western Blot) (Western blot analysis of GARS on Raji cells lysates using anti-GARS antibody at 1/1, 000 dilution.)
Related Product Information for anti-GARS antibody
The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Proteins belonging to this family function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. GlyRS (Glycyl-tRNA synthetase), also known as Glycine-tRNA ligase, is a 739 amino acid class II synthetase that is widely expressed, including in the brain and spinal cord. Defects in the gene encoding GlyRS is the cause of Charcot-Marie-Tooth disease type 2D (CMT2D), which is an autosomal dominant inherited disease characterized by severe weakness, atrophy and absence of deep tendon reflexes in the upper extremities. Defects in the GlyRS gene is also the cause of distal hereditary muscular neuropathy type V (HMN5), a disease similar to CMT2D, though the distal sensory involvement is less severe in HMN5 patients.
Product Categories/Family for anti-GARS antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
83,166 Da
NCBI Official Full Name
glycine--tRNA ligase
NCBI Official Synonym Full Names
glycyl-tRNA synthetase
NCBI Official Symbol
GARS
NCBI Official Synonym Symbols
HMN5; CMT2D; DSMAV; GlyRS; SMAD1
NCBI Protein Information
glycine--tRNA ligase; AP-4-A synthetase; Charcot-Marie-Tooth neuropathy 2D; Charcot-Marie-Tooth neuropathy, neuronal type, D; diadenosine tetraphosphate synthetase; glycine tRNA ligase
UniProt Protein Name
Glycine--tRNA ligase
UniProt Gene Name
GARS
UniProt Synonym Gene Names
AP-4-A synthetase; GlyRS
UniProt Entry Name
SYG_HUMAN

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Product Notes

The GARS gars (Catalog #AAA312268) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GARS Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GARS can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GARS gars for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GARS, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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