ChIP (Chromatin Immunoprecipitation)
(Chromatin immunoprecipitation analysis of HeLa cells genomic DNA(gDNA) using DNA-RNA hybrid Mouse Monoclonal Antibody [S9.6] at dilution of 1:200.)
Mouse anti-All DNA-RNA Hybrid Monoclonal Antibody | anti-DNA-RNA antibody
DNA-RNA Hybrid Monoclonal Antibody [S9.6]
Reactivity
All
Applications
Chromatin Immunoprecipitation, Immunoprecipitation, Immunofluorescence
Purity
Protein A/G Purification
Synonyms
DNA-RNA Hybrid, Antibody; DNA-RNA Hybrid Monoclonal Antibody [S9.6]; DNA-RNA hybrid; RNA/DNA hybrid; anti-DNA-RNA antibody
Host
Mouse
Reactivity
All
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
S9.6
Purity/Purification
Protein A/G Purification
Form/Format
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-DNA-RNA antibody
ChIP (Chromatin immunoprecipitation), IF (Immunofluorescence)
Immunogen
phiX174 bacteriophage-derived synthetic DNA/RNA
Preparation and Storage
Store at -20 degree C Valid for 12 months. Avoid freeze/thaw cycles.
ChIP (Chromatin Immunoprecipitation)
(Chromatin immunoprecipitation analysis of HeLa cells genomic DNA(gDNA) using DNA-RNA hybrid Mouse Monoclonal Antibody [S9.6] at dilution of 1:200.)
ChIP (Chromatin Immunoprecipitation)
(Chromatin immunoprecipitation analysis of HeLa cells genomic DNA(gDNA) using DNA-RNA hybrid Mouse Monoclonal Antibody [S9.6] at dilution of 1:200.)
IF (Immunofluorescence)
(Immunofluorescent analysis of (4% PFA) fixed HeLa cells using anti-DNA-RNA hybrid Mouse Monoclonal Antibody [S9.6] at dilution of 1:500.)
IF (Immunofluorescence)
(Immunofluorescent analysis of (4% PFA) fixed HeLa cells using anti-DNA-RNA hybrid Mouse Monoclonal Antibody [S9.6] at dilution of 1:500.)
IF (Immunofluorescence)
(Immunofluorescentanalysis of (4% PFA) fixed HeLa cells using DNA-RNA hybrid mouse monoclonal antibody [S9.6] at dilution of 1:500.)
IF (Immunofluorescence)
(Immunofluorescentanalysis of (4% PFA) fixed HeLa cells using DNA-RNA hybrid mouse monoclonal antibody [S9.6] at dilution of 1:500.)
Related Product Information for anti-DNA-RNA antibody
The DNA-RNA hybrids are a natural occurrence within eukaryotic cells and their level are high at sites of high transcriptional activity. They are non-canonical nucleic acid structures with transcriptional regulatory functions. Their presence is reported to predispose a locus to chromosomal breakage. The S9.6 monoclonal antibody recognizes DNA-RNA hybrids (also known as R-loops) and does not bind to single or double stranded DNA. The antibody has high affinity for DNA?RNA hybrids but also binds RNA-RNA hybrids that are AU-rich. The specificity of the antibody appears to be determined by a combination of sequence and structural dependency since R?loop sequence affects binding affinity.
Product Categories/Family for anti-DNA-RNA antibody
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Product Notes
The DNA-RNA (Catalog #AAA179818) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DNA-RNA Hybrid Monoclonal Antibody [S9.6] reacts with All and may cross-react with other species as described in the data sheet. AAA Biotech's DNA-RNA Hybrid can be used in a range of immunoassay formats including, but not limited to, ChIP (Chromatin immunoprecipitation), IF (Immunofluorescence). Researchers should empirically determine the suitability of the DNA-RNA for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNA-RNA Hybrid, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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