SDS-PAGE
(SDS-PAGE Analysis Purified Band III Mouse Monoclonal Antibody (Q1/156). Confirmation of Purity and Integrity of Antibody.)
Mouse anti-Human Band III Monoclonal Antibody | anti-SLC4A1 antibody
Band III
Gene Names
SLC4A1; DI; FR; SW; WD; WR; AE1; CHC; SAO; WD1; BND3; EPB3; SPH4; CD233; EMPB3; RTA1A
Reactivity
Human
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Purified Ab with BSA and Azide at 200ug/ml
Synonyms
Band III, Antibody; Band III; AE1; Anion exchange protein 1; BND3; CD233; DI; Diego blood group; EMPB3; EPB3; Erythrocyte membrane protein band 3; Erythroid anion exchange protein; FR; Froese blood group; RTA1A; SLC4A1; Solute carrier family 4 member 1; SW; Swann blood group; Waldner blood group; WD1; WR; Wright blood group antibody; anti-SLC4A1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
Q1/156
Specificity
Band 3, also designated AE1, is an erythrocyte membrane glycoprotein that contributes to cell stuctural integrity and mediates exchange of chloride and bicarbonate across the phospholipid bilayer. The diverse functions of the approximately 900 amino acid protein are mediated by two distinct domains. The amino-terminal domain, also known as cdb3 for cytoplasmic domain of erthrocyte membrane band 3, acts as an attachment site for the erythrocyte skeleton by binding ankyrin. The carboxy-terminal, membrane-associated domain carries out exchange transport of anions. Degradation of band 3 can generate an aging antigen known as senescent cell antigen, or SCA, which is expressed on old cells and marks them for removal by the immune system. An isoform of band 3, which lacks the first 65 amino acids and does not bind ankryin, is expressed in kidney.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml
Form/Format
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide.
Sequence Length
911
Applicable Applications for anti-SLC4A1 antibody
WB (Western Blot), IF (Immunofluorescence), ELISA
Positive Control
Red blood cell lysate; Human colon and lung tissue.
Immunogen
Human fetal liver cells.
Cellular Localization
Cell Membrane
Hu-chromosome Location
17q21.31
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C.
Non-hazardous. No MSDS required.
Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified Band III Mouse Monoclonal Antibody (Q1/156). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified Band III Mouse Monoclonal Antibody (Q1/156). Confirmation of Purity and Integrity of Antibody.)
References
Brock, C.J., Tanner, M.J. and Kempf, C. 1983. Biochem. J. 213: 577-586
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
95kDa
NCBI Official Full Name
band 3 anion transport protein
NCBI Official Synonym Full Names
solute carrier family 4 member 1 (Diego blood group)
NCBI Official Symbol
SLC4A1
NCBI Official Synonym Symbols
DI; FR; SW; WD; WR; AE1; CHC; SAO; WD1; BND3; EPB3; SPH4; CD233; EMPB3; RTA1A
NCBI Protein Information
band 3 anion transport protein
UniProt Protein Name
Band 3 anion transport protein
UniProt Gene Name
SLC4A1
UniProt Synonym Gene Names
AE1; DI; EPB3; AE 1; Anion exchanger 1
UniProt Entry Name
B3AT_HUMAN
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Product Notes
The SLC4A1 slc4a1 (Catalog #AAA215199) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Band III reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Band III can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence), ELISA. Researchers should empirically determine the suitability of the SLC4A1 slc4a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Band III, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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