Mouse Aciculin/Phosphoglucomutase 5 (PGM5) Monoclonal Antibody | anti-PGM5 antibody

Aciculin/Phosphoglucomutase 5 (PGM5)

Cat. Num. AAA215380

• Gene Names: PGM5; PGMRP
• Reactivity: Human, Cow, Mouse, Rat, Rabbit Predicted to react with Porcine, Avian, Frog
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
• Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: Aciculin/Phosphoglucomutase 5 (PGM5), Antibody; Aciculin/Phosphoglucomutase 5 (PGM5); Aciculin; PGM-RP; PGM5; PGMRP; phosphoglucomutase 5; Phosphoglucomutase-like protein 5; Phosphoglucomutase-related protein; anti-PGM5 antibody

• Host: Mouse
• Reactivity: Human, Cow, Mouse, Rat, Rabbit Predicted to react with Porcine, Avian, Frog
• Clonality: Monoclonal
• Isotype: Ig1c, kappa
• Clone Number: 14F8/F8
• Specificity: Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 219

• Applicable Applications for anti-PGM5 antibody: WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA
• Immunogen: Cytoskeletal fraction of theHuman myometrium tissue extract
• Cellular Localization: Cytoplasm
• Hu-chromosome Location: 9q21.11
• Positive Control: Human heart muscle or Smooth muscle (IHC). Mouse heart tissue lysate (WB).
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C.; Antibody without azide: store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified Aciculin Mouse Monoclonal Antibody (14F8/F8). Confirmation of Purity and Integrity of Antibody.)

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human uterus stained with Aciculin Mouse Monoclonal Antibody (14F8/F8).)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human bladder stained with Aciculin Mouse Monoclonal Antibody (14F8/F8).)

References

Belkin, A.M. and Burridge, K. 1994. Expression and localization of the phosphoglucomutase-related cytoskeletal protein, Aciculin, in skeletal muscle. J. Cell Sci. 107: 1993-2003.

NCBI and Uniprot Product Information

• NCBI GI #: 119582864
• NCBI GeneID: 5239
• UniProt Accession #: Q15124
• Molecular Weight: 56kDa
• NCBI Official Full Name: phosphoglucomutase 5, partial
• NCBI Official Synonym Full Names: phosphoglucomutase 5
• NCBI Official Symbol: PGM5
• NCBI Official Synonym Symbols: PGMRP
• NCBI Protein Information: phosphoglucomutase-like protein 5
• UniProt Protein Name: Phosphoglucomutase-like protein 5
• UniProt Gene Name: PGM5
• UniProt Synonym Gene Names: PGMRP; PGM-RP