Standard Curve (Sample)
(Fig.1. Human Reticulon-4 receptor (RTN4R) Standard Curve.)
Human Reticulon-4 Receptor (RTN4R) ELISA Kit | RTN4R elisa kit
Human Reticulon-4 Receptor (RTN4R) ELISA Kit
Gene Names
RTN4R; NGR; NOGOR
Reactivity
Human
Synonyms
Reticulon-4 Receptor (RTN4R); N/A; Human Reticulon-4 Receptor (RTN4R) ELISA Kit; RTN4R; NGR; NOGOR; Nogo-66 receptor; OTTHUMP00000197866; UNQ330/PRO526; nogo receptor; RTN4R elisa kit
Reactivity
Human
Specificity
Human Reticulon-4 receptor (RTN4R) ELISA Kit has high sensitivity and excellent specificity for detection of Human RTN4R. No significant cross-reactivity or interference between Human RTN4R and analogues was observed.
Sequence Length
473
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Standard Curve (Sample)
(Fig.1. Human Reticulon-4 receptor (RTN4R) Standard Curve.)
Standard Curve (Sample)
(Fig.1. Human Reticulon-4 receptor (RTN4R) Standard Curve.)
Related Product Information for RTN4R elisa kit
Description: This Human Reticulon-4 receptor (RTN4R) ELISA Kit employs a two-site sandwich ELISA to quantitate RTN4R in samples. An antibody specific for RTN4R has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any RTN4R present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for RTN4R is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of RTN4R bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: Reticulon 4 receptor is the receptor for reticulon 4, oligodendrocytemyelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. The Nogo-66 Receptor (NgR) is a high affinity binding receptor for a region of Nogo, a myelin associated protein that inhibits axon outgrowth. NgR was identified by Strittmatter and colleagues using an expression cloning strategy.NgR is implicated in neuronal plasticity and regeneration. Its relative importance in mediating myelin inhibition in vitro and in vivo is currently under intense investigation, since this protein might be a good drug target for treatment of various neurological conditions such as spinal cord injury and stroke.
Background: Reticulon 4 receptor is the receptor for reticulon 4, oligodendrocytemyelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. The Nogo-66 Receptor (NgR) is a high affinity binding receptor for a region of Nogo, a myelin associated protein that inhibits axon outgrowth. NgR was identified by Strittmatter and colleagues using an expression cloning strategy.NgR is implicated in neuronal plasticity and regeneration. Its relative importance in mediating myelin inhibition in vitro and in vivo is currently under intense investigation, since this protein might be a good drug target for treatment of various neurological conditions such as spinal cord injury and stroke.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Reticulon-4 receptor
NCBI Official Synonym Full Names
reticulon 4 receptor
NCBI Official Symbol
RTN4R
NCBI Official Synonym Symbols
NGR; NOGOR
NCBI Protein Information
reticulon-4 receptor
UniProt Protein Name
Reticulon-4 receptor
UniProt Gene Name
RTN4R
UniProt Synonym Gene Names
NOGOR; NgR
UniProt Entry Name
RTN4R_HUMAN
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Product Notes
The Human RTN4R rtn4r (Catalog #AAA330978) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA330978 ELISA Kit recognizes Human RTN4R. It is sometimes possible for the material contained within the vial of "Reticulon-4 Receptor (RTN4R), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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