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product-image-AAA124170_SC15.jpg Standard Curve (Sample) (Typical Testing Data/Standard Curve (for reference only))

Human Plasma Protease C1 Inhibitor, SERPING1 ELISA Kit | SERPING1 elisa kit

Human Plasma Protease C1 Inhibitor, SERPING1 Primacu ELISA Kit

Gene Names
SERPING1; C1IN; C1NH; HAE1; HAE2; C1INH
Reactivity
Human
Synonyms
Plasma Protease C1 Inhibitor, SERPING1; N/A; Human Plasma Protease C1 Inhibitor, SERPING1 Primacu ELISA Kit; Plasma protease C1 inhibitor; C1 inhibitor; C1IN; C1NH; SERPING1 elisa kit
Ordering
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
125-8000pg/mL
Sensitivity
31.17pg/mL
Standard Solution
40ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C

Standard Curve (Sample)

(Typical Testing Data/Standard Curve (for reference only))

product-image-AAA124170_SC15.jpg Standard Curve (Sample) (Typical Testing Data/Standard Curve (for reference only))
Related Product Information for SERPING1 elisa kit
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides and E-selectin. Owing to this moiety, C1-INH intervenes in regulation of the inflammatory reaction. The heterozygous deficiency of C1-INH results in hereditary angioedema (HAE). Owing to its ability to modulate the contact and complement systems and the convincing safety profile, plasma-derived C1 inhibitor is an attractive therapeutic protein to treat inflammatory diseases other than HAE. Deficiency of C1 inhibitor results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. C1 inhibitor may prove useful in a variety of other diseases including septic shock, reperfusion injury, hyperacute transplant rejection, traumatic and hemorrhagic shock, and the increased vascular permeability associated with thermal injury, interleukin-2 therapy and cardiopulmonary bypass.
Product Categories/Family for SERPING1 elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
710
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,154 Da
NCBI Official Full Name
plasma protease C1 inhibitor
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
NCBI Official Symbol
SERPING1
NCBI Official Synonym Symbols
C1IN; C1NH; HAE1; HAE2; C1INH
NCBI Protein Information
plasma protease C1 inhibitor; serpin G1; C1-inhibiting factor; C1 esterase inhibitor; complement component 1 inhibitor; serine/cysteine proteinase inhibitor clade G member 1
UniProt Protein Name
Plasma protease C1 inhibitor
UniProt Gene Name
SERPING1
UniProt Synonym Gene Names
C1IN; C1NH; C1 Inh; C1Inh
UniProt Entry Name
IC1_HUMAN

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Product Notes

The Human SERPING1 serping1 (Catalog #AAA124170) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124170 ELISA Kit recognizes Human SERPING1. It is sometimes possible for the material contained within the vial of "Plasma Protease C1 Inhibitor, SERPING1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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