Human Neuropilin-2, NRP2 ELISA Kit | NRP2 elisa kit
Human Neuropilin-2, NRP2 Primacu ELISA Kit
Gene Names
NRP2; NP2; NPN2; PRO2714; VEGF165R2
Reactivity
Human
Synonyms
Neuropilin-2, NRP2; N/A; Human Neuropilin-2, NRP2 Primacu ELISA Kit; Neuropilin-2; VEGF165R2; NRP2 elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
156.25-10000pg/mL
Sensitivity
31.69pg/mL
Standard Solution
100ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Related Product Information for NRP2 elisa kit
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation factor V/VIII homology domains, and a MAM (meprin, tyrosine phosphatase domain) region. NRP-2 is a receptor capable of binding two disparate ligands, classIII semaphorins (SEMA) and vascular endothelial growth factors (VEGF), and thus regulates two diverse systems by activating cellular signaling pathways via interacting with other cell surface receptors such as VEGF receptors and plexins. NRP-2 is well known for its role in facilitating axonal guidance during the development of the neuronal system, and additionally, it is also expressed in vascular endothelial cells and lymphatic endothelium where it affects proliferation, migration, angiogenesis, as well as the formation of small lymphatic vessels and capillaries. A recent study has identified NRP-2 as a polysialylation protein expressed in human dendritic cells and modulates DC-T Cell Interactions. Nearly all tumor cells express neuropilins and NRP-2 is predominantly expressed in neuronal tumors and melanomas. Furthermore, it is suggested that as the specific ligand for NRP-2, SEMA 3F inhibits tumor angiogenesis, and metastasis.
Product Categories/Family for NRP2 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
104,859 Da
NCBI Official Full Name
vascular endothelial cell growth factor 165 receptor 2
NCBI Official Synonym Full Names
neuropilin 2
NCBI Official Symbol
NRP2
NCBI Official Synonym Symbols
NP2; NPN2; PRO2714; VEGF165R2
NCBI Protein Information
neuropilin-2; neuropilin-2b(0); neuropilin-2a(17); neuropilin-2a(22); receptor for VEGF165 and semaphorins class3; vascular endothelial cell growth factor 165 receptor 2
UniProt Protein Name
Neuropilin-2
UniProt Gene Name
NRP2
UniProt Synonym Gene Names
VEGF165R2
UniProt Entry Name
NRP2_HUMAN
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Product Notes
The Human NRP2 nrp2 (Catalog #AAA124101) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124101 ELISA Kit recognizes Human NRP2. It is sometimes possible for the material contained within the vial of "Neuropilin-2, NRP2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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